Motif ID: Zkscan3

Z-value: 0.330


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.572.1e-06Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102365111 2.010 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr8_+_106893616 1.429 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr18_+_61105844 1.393 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr5_+_24985840 1.261 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_-_106893581 1.106 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr2_+_104095796 1.015 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr8_-_106893515 0.997 ENSMUST00000176090.1
 Chtf8
CTF8, chromosome transmission fidelity factor 8
chr5_-_73338580 0.861 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr6_-_122856151 0.851 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr8_-_105758570 0.846 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr2_+_104069819 0.819 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
 Cd59b


CD59b antigen


chr6_-_97459279 0.793 ENSMUST00000113359.1
 Frmd4b
FERM domain containing 4B
chr19_-_10869757 0.782 ENSMUST00000120524.1
ENSMUST00000025645.7
 Tmem132a

transmembrane protein 132A

chr7_-_81345189 0.717 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr2_+_32646586 0.715 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr11_-_75422586 0.699 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_31670714 0.694 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr8_+_70616816 0.694 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr2_+_156613664 0.667 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr11_-_75422524 0.651 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 2.0 GO:0015701 response to activity(GO:0014823) bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)
0.2 1.8 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3 1.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.7 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.7 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.5 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.3 2.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 1.4 GO:0034455 t-UTP complex(GO:0034455)
0.5 1.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.4 GO:0043203 axon hillock(GO:0043203)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.2 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.4 GO:0005816 spindle pole body(GO:0005816)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 1.8 GO:0001848 complement binding(GO:0001848)
0.0 1.4 GO:0019955 cytokine binding(GO:0019955)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 0.9 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.8 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.2 0.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)