Motif ID: Zkscan3

Z-value: 0.330


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.572.1e-06Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_102365111 2.010 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr8_+_106893616 1.429 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr18_+_61105844 1.393 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr5_+_24985840 1.261 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_-_106893581 1.106 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
 Chtf8



CTF8, chromosome transmission fidelity factor 8



chr2_+_104095796 1.015 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr8_-_106893515 0.997 ENSMUST00000176090.1
 Chtf8
CTF8, chromosome transmission fidelity factor 8
chr5_-_73338580 0.861 ENSMUST00000087195.5
 Ociad2
OCIA domain containing 2
chr6_-_122856151 0.851 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr8_-_105758570 0.846 ENSMUST00000155038.2
ENSMUST00000013294.9
 Gfod2

glucose-fructose oxidoreductase domain containing 2

chr2_+_104069819 0.819 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
 Cd59b


CD59b antigen


chr6_-_97459279 0.793 ENSMUST00000113359.1
 Frmd4b
FERM domain containing 4B
chr19_-_10869757 0.782 ENSMUST00000120524.1
ENSMUST00000025645.7
 Tmem132a

transmembrane protein 132A

chr7_-_81345189 0.717 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr2_+_32646586 0.715 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr11_-_75422586 0.699 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_31670714 0.694 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr8_+_70616816 0.694 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr2_+_156613664 0.667 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr11_-_75422524 0.651 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr6_+_125552948 0.633 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr8_-_116978908 0.604 ENSMUST00000070577.5
 1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr11_-_88851462 0.603 ENSMUST00000107903.1
 Akap1
A kinase (PRKA) anchor protein 1
chr17_-_35673738 0.603 ENSMUST00000001565.8
 Gtf2h4
general transcription factor II H, polypeptide 4
chr7_+_101896340 0.594 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr2_-_30194112 0.545 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr17_+_46110982 0.540 ENSMUST00000024763.3
ENSMUST00000123646.1
 Mrps18a

mitochondrial ribosomal protein S18A

chr7_+_126759601 0.528 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr17_-_35673517 0.515 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
 Gtf2h4



general transcription factor II H, polypeptide 4



chr19_+_6276725 0.496 ENSMUST00000025684.3
 Ehd1
EH-domain containing 1
chr5_-_88675613 0.496 ENSMUST00000113234.1
ENSMUST00000153565.1
 Grsf1

G-rich RNA sequence binding factor 1

chr1_-_40790642 0.493 ENSMUST00000039672.5
 Mfsd9
major facilitator superfamily domain containing 9
chr13_-_38658991 0.491 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr2_+_155775333 0.476 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr8_+_33732237 0.460 ENSMUST00000171010.1
 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr2_-_66634952 0.442 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha

chr9_+_114688782 0.420 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr2_+_121295437 0.417 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr10_+_80629646 0.397 ENSMUST00000085435.5
 Csnk1g2
casein kinase 1, gamma 2
chr5_-_88675190 0.397 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1

chr8_+_31091593 0.390 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr8_-_124897685 0.377 ENSMUST00000098312.2
 Exoc8
exocyst complex component 8
chr4_+_63544747 0.320 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr7_-_27228605 0.307 ENSMUST00000003850.7
 Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr5_+_117976761 0.306 ENSMUST00000035579.6
 Fbxo21
F-box protein 21
chr13_-_19395728 0.296 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr18_-_34651703 0.293 ENSMUST00000025228.5
ENSMUST00000133181.1
 Cdc23

CDC23 cell division cycle 23

chr3_+_146500071 0.289 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr7_-_98178254 0.287 ENSMUST00000040971.7
 Capn5
calpain 5
chr13_+_44730726 0.283 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
 Jarid2


jumonji, AT rich interactive domain 2


chr4_+_139192899 0.279 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
 Capzb


capping protein (actin filament) muscle Z-line, beta


chr8_+_71396853 0.262 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chr18_+_82554463 0.253 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
 Mbp










myelin basic protein










chr2_+_121171155 0.232 ENSMUST00000110658.1
 Tubgcp4
tubulin, gamma complex associated protein 4
chr11_+_116918844 0.224 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr8_+_94810446 0.210 ENSMUST00000034232.1
 Ccl17
chemokine (C-C motif) ligand 17
chr2_+_121171204 0.209 ENSMUST00000039541.5
ENSMUST00000110657.1
 Tubgcp4

tubulin, gamma complex associated protein 4

chr13_+_42709482 0.195 ENSMUST00000066928.5
ENSMUST00000148891.1
 Phactr1

phosphatase and actin regulator 1

chr1_+_132298606 0.190 ENSMUST00000046071.4
 Klhdc8a
kelch domain containing 8A
chr14_+_57424054 0.187 ENSMUST00000122063.1
 Ift88
intraflagellar transport 88
chrX_-_75874536 0.184 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr14_+_51893610 0.173 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr3_+_146499850 0.154 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr6_+_127453705 0.139 ENSMUST00000039680.5
 Parp11
poly (ADP-ribose) polymerase family, member 11
chr7_-_127020321 0.132 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr1_+_135232045 0.095 ENSMUST00000110798.3
 Gm4204
predicted gene 4204
chr8_-_70760889 0.067 ENSMUST00000038626.8
 Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr13_-_104109576 0.039 ENSMUST00000109315.3
 Nln
neurolysin (metallopeptidase M3 family)
chr11_-_102218923 0.030 ENSMUST00000131254.1
 Hdac5
histone deacetylase 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.3 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 2.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.7 GO:0003032 detection of oxygen(GO:0003032)
0.2 1.8 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.2 0.7 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 2.0 GO:0015701 response to activity(GO:0014823) bicarbonate transport(GO:0015701) response to arsenic-containing substance(GO:0046685)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.4 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.5 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0034455 t-UTP complex(GO:0034455)
0.5 1.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 2.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.4 GO:0005816 spindle pole body(GO:0005816)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.1 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.4 GO:0043203 axon hillock(GO:0043203)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.2 0.7 GO:0005534 galactose binding(GO:0005534)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 2.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 1.8 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 1.4 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)