Motif ID: Zscan4c

Z-value: 1.141


Transcription factors associated with Zscan4c:

Gene SymbolEntrez IDGene Name
Zscan4c ENSMUSG00000054272.5 Zscan4c



Activity profile for motif Zscan4c.

activity profile for motif Zscan4c


Sorted Z-values histogram for motif Zscan4c

Sorted Z-values for motif Zscan4c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zscan4c

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 23.332 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr4_+_49059256 14.533 ENSMUST00000076670.2
 E130309F12Rik
RIKEN cDNA E130309F12 gene
chr8_+_118283719 14.403 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr7_+_130936172 14.239 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr4_-_46991842 13.866 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_-_78718113 11.633 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr9_+_26733728 9.780 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
 B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr9_-_49798905 9.770 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chr3_-_158562199 9.738 ENSMUST00000106044.1
 Lrrc7
leucine rich repeat containing 7
chr9_-_49798729 9.324 ENSMUST00000166811.2
 Ncam1
neural cell adhesion molecule 1
chr16_+_45094036 9.040 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chr18_-_23041641 8.061 ENSMUST00000097651.3
 Nol4
nucleolar protein 4
chr9_+_26733845 7.074 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr9_+_89909775 6.909 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr2_+_68861564 6.245 ENSMUST00000176018.1
 Cers6
ceramide synthase 6
chr9_+_57940104 6.122 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr2_-_36105271 6.115 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr14_-_60177482 6.068 ENSMUST00000140924.1
 Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr11_+_16257706 5.912 ENSMUST00000109645.2
ENSMUST00000109647.2
 Vstm2a

V-set and transmembrane domain containing 2A

chr13_+_58807884 5.815 ENSMUST00000079828.5
 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 23.3 GO:0021542 dentate gyrus development(GO:0021542)
6.4 19.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.8 16.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
3.6 14.4 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
2.4 14.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.5 13.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 12.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 11.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.2 9.8 GO:0008542 visual learning(GO:0008542)
0.1 9.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.0 9.5 GO:0007379 segment specification(GO:0007379)
1.3 9.4 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 9.4 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.4 6.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
1.2 6.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.0 6.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.9 6.1 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.0 5.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.9 5.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.0 5.0 GO:2001025 positive regulation of response to drug(GO:2001025)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 39.6 GO:0031225 anchored component of membrane(GO:0031225)
2.8 13.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.6 9.7 GO:0005614 interstitial matrix(GO:0005614)
0.3 9.7 GO:0043194 axon initial segment(GO:0043194)
0.2 9.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 7.0 GO:0031012 extracellular matrix(GO:0031012)
0.3 6.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 6.1 GO:0005802 trans-Golgi network(GO:0005802)
0.2 5.8 GO:0048786 presynaptic active zone(GO:0048786)
0.2 5.6 GO:0030673 axolemma(GO:0030673)
0.8 5.0 GO:1990635 proximal dendrite(GO:1990635)
0.5 4.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 3.5 GO:0005915 zonula adherens(GO:0005915)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.9 2.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.8 GO:0043679 axon terminus(GO:0043679)
0.4 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 30.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.0 19.1 GO:0030275 LRR domain binding(GO:0030275)
2.8 16.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.9 14.4 GO:0055100 adiponectin binding(GO:0055100)
0.6 14.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
2.3 13.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 11.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.3 11.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 9.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.5 9.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 8.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 7.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.6 6.1 GO:0038191 neuropilin binding(GO:0038191)
0.3 6.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.2 5.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.4 5.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 5.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 5.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 4.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 4.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)