Motif ID: Arid5b

Z-value: 0.401


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_682787350.183.2e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_107567445 1.508 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr5_-_31697598 1.455 ENSMUST00000031018.7
 Rbks
ribokinase
chr4_+_132638987 1.140 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
 Eya3




eyes absent 3 homolog (Drosophila)




chr15_+_37233036 1.079 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
 Grhl2


grainyhead-like 2 (Drosophila)


chr12_-_10900296 1.078 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr3_+_34649987 1.008 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr18_-_15063560 0.995 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chrX_+_140456613 0.992 ENSMUST00000033809.3
 Prps1
phosphoribosyl pyrophosphate synthetase 1
chr6_+_120666388 0.939 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr5_+_115908644 0.925 ENSMUST00000141101.1
 Cit
citron
chr15_-_55548164 0.852 ENSMUST00000165356.1
 Mrpl13
mitochondrial ribosomal protein L13
chr15_+_52040107 0.843 ENSMUST00000090025.4
 Aard
alanine and arginine rich domain containing protein
chr2_+_25180737 0.800 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr12_+_108792946 0.783 ENSMUST00000021692.7
 Yy1
YY1 transcription factor
chr1_+_180568913 0.761 ENSMUST00000027777.6
 Parp1
poly (ADP-ribose) polymerase family, member 1
chr8_-_11008458 0.691 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr15_-_13173607 0.654 ENSMUST00000036439.4
 Cdh6
cadherin 6
chrM_+_8600 0.643 ENSMUST00000082409.1
 mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr2_-_84678828 0.636 ENSMUST00000111665.1
 Tmx2
thioredoxin-related transmembrane protein 2
chr15_+_78842632 0.615 ENSMUST00000059619.1
 Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr3_-_95882031 0.594 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr9_+_87022014 0.549 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chrX_-_157492280 0.474 ENSMUST00000112529.1
 Sms
spermine synthase
chr1_+_180330470 0.461 ENSMUST00000070181.6
 Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr4_-_150909428 0.447 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
 Park7


Parkinson disease (autosomal recessive, early onset) 7


chr2_+_76650264 0.446 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr2_-_84678051 0.442 ENSMUST00000053664.8
ENSMUST00000111664.1
 Tmx2

thioredoxin-related transmembrane protein 2

chr4_+_105157339 0.427 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr15_-_44428303 0.413 ENSMUST00000038719.6
 Nudcd1
NudC domain containing 1
chr2_-_151744142 0.400 ENSMUST00000109869.1
 Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr10_+_94576254 0.390 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr4_-_129662442 0.385 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr14_-_47394253 0.380 ENSMUST00000177822.1
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr18_+_23415400 0.342 ENSMUST00000115832.2
ENSMUST00000047954.7
 Dtna

dystrobrevin alpha

chr4_+_122836236 0.339 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr16_+_32431225 0.337 ENSMUST00000115140.1
 Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr9_-_42461414 0.313 ENSMUST00000066179.7
 Tbcel
tubulin folding cofactor E-like
chr12_-_91746020 0.312 ENSMUST00000166967.1
 Ston2
stonin 2
chr5_+_31494736 0.269 ENSMUST00000076949.6
ENSMUST00000117700.1
 Gpn1

GPN-loop GTPase 1

chr3_-_19264959 0.268 ENSMUST00000121951.1
 Pde7a
phosphodiesterase 7A
chr3_-_95882193 0.265 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr10_+_14523062 0.231 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr9_+_122117338 0.230 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase


chr7_-_101921186 0.172 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr9_-_106789130 0.165 ENSMUST00000046502.5
 Rad54l2
RAD54 like 2 (S. cerevisiae)
chr11_-_110251736 0.158 ENSMUST00000044003.7
 Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chrX_-_101222426 0.144 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr11_-_32267547 0.143 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
 Nprl3


nitrogen permease regulator-like 3


chr2_+_84678396 0.113 ENSMUST00000102645.3
 Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr15_+_44428073 0.079 ENSMUST00000060652.3
 Eny2
enhancer of yellow 2 homolog (Drosophila)
chr3_-_89998656 0.067 ENSMUST00000079724.4
 Hax1
HCLS1 associated X-1
chrX_+_47912387 0.067 ENSMUST00000001202.8
ENSMUST00000115020.1
 Ocrl

oculocerebrorenal syndrome of Lowe

chr9_-_45984816 0.065 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr4_-_75278246 0.043 ENSMUST00000030103.8
 Tmem261
transmembrane protein 261
chr3_-_19265007 0.040 ENSMUST00000091314.4
 Pde7a
phosphodiesterase 7A
chr12_+_110601439 0.030 ENSMUST00000018851.7
 Dync1h1
dynein cytoplasmic 1 heavy chain 1
chrX_-_150812932 0.016 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
 Maged2


melanoma antigen, family D, 2


chr3_+_95588990 0.008 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr3_-_95882232 0.002 ENSMUST00000161866.1
 Gm129
predicted gene 129
chr10_+_127420867 0.001 ENSMUST00000064793.6
 R3hdm2
R3H domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.3 0.8 GO:0040009 regulation of growth rate(GO:0040009) protein poly-ADP-ribosylation(GO:0070212)
0.2 1.5 GO:0019321 pentose metabolic process(GO:0019321)
0.2 1.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
0.1 1.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.9 GO:0001842 neural fold formation(GO:0001842)
0.1 0.5 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.8 GO:0010225 response to UV-C(GO:0010225)
0.0 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0022904 respiratory electron transport chain(GO:0022904)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 0.9 GO:0090537 CERF complex(GO:0090537)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
0.1 0.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)