Motif ID: Atf1_Creb5

Z-value: 0.779

Transcription factors associated with Atf1_Creb5:

Gene SymbolEntrez IDGene Name
Atf1 ENSMUSG00000023027.6 Atf1
Creb5 ENSMUSG00000053007.6 Creb5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf1mm10_v2_chr15_+_100227871_100227878-0.441.1e-02Click!
Creb5mm10_v2_chr6_+_53573364_53573394-0.163.6e-01Click!


Activity profile for motif Atf1_Creb5.

activity profile for motif Atf1_Creb5


Sorted Z-values histogram for motif Atf1_Creb5

Sorted Z-values for motif Atf1_Creb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf1_Creb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_23761223 4.604 ENSMUST00000102964.2
 Hist1h4a
histone cluster 1, H4a
chr19_-_61228396 4.209 ENSMUST00000076046.6
 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr10_+_29211637 4.191 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr6_-_55681257 3.943 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr12_+_79130777 3.784 ENSMUST00000021550.6
 Arg2
arginase type II
chr9_-_96752822 3.661 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr7_-_126949499 3.631 ENSMUST00000106339.1
ENSMUST00000052937.5
 Asphd1

aspartate beta-hydroxylase domain containing 1

chr2_+_155276297 3.389 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr11_+_101468164 3.186 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr12_+_102554966 3.105 ENSMUST00000021610.5
 Chga
chromogranin A
chrX_-_21061981 2.782 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
 Zfp182


zinc finger protein 182


chrX_+_170009659 2.769 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr15_-_84105662 2.550 ENSMUST00000082365.5
 Sult4a1
sulfotransferase family 4A, member 1
chr13_-_22042949 2.454 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr2_+_132781278 2.440 ENSMUST00000028826.3
 Chgb
chromogranin B
chr11_+_113619318 2.434 ENSMUST00000146390.2
ENSMUST00000106630.1
 Sstr2

somatostatin receptor 2

chr7_+_130865835 2.352 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr5_-_124032214 2.336 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr6_+_54681687 2.307 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr7_+_130865756 2.274 ENSMUST00000120441.1
 Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 159 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 4.6 GO:0001553 luteinization(GO:0001553)
0.4 4.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2 4.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 4.0 GO:0016579 protein deubiquitination(GO:0016579)
1.3 3.8 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
0.4 3.7 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 3.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 3.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.0 3.1 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 2.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 2.4 GO:0030432 peristalsis(GO:0030432)
0.2 2.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 2.4 GO:0006342 chromatin silencing(GO:0006342)
0.8 2.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.4 2.2 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.5 1.9 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 1.9 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.9 GO:0000786 nucleosome(GO:0000786)
0.3 5.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 4.6 GO:0032587 ruffle membrane(GO:0032587)
0.2 3.8 GO:0000421 autophagosome membrane(GO:0000421)
0.3 3.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 3.2 GO:0035253 ciliary rootlet(GO:0035253)
0.6 3.1 GO:0042583 chromaffin granule(GO:0042583)
0.1 3.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 2.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0042393 histone binding(GO:0042393)
0.1 5.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 4.7 GO:0008242 omega peptidase activity(GO:0008242)
0.2 4.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 4.5 GO:0005125 cytokine activity(GO:0005125)
0.0 4.5 GO:0015631 tubulin binding(GO:0015631)
0.1 4.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.6 3.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 3.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 3.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 3.6 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.4 3.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 2.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 2.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.8 2.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 2.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.7 2.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)