Motif ID: Atf3

Z-value: 0.693


Transcription factors associated with Atf3:

Gene SymbolEntrez IDGene Name
Atf3 ENSMUSG00000026628.8 Atf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf3mm10_v2_chr1_-_191183244_1911833400.621.0e-04Click!


Activity profile for motif Atf3.

activity profile for motif Atf3


Sorted Z-values histogram for motif Atf3

Sorted Z-values for motif Atf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 4.955 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr11_+_32276400 2.812 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr4_-_134012381 2.079 ENSMUST00000176113.1
 Lin28a
lin-28 homolog A (C. elegans)
chr12_-_10900296 1.976 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr18_-_41951187 1.941 ENSMUST00000070949.4
 Prelid2
PRELI domain containing 2
chr1_+_52008210 1.915 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr14_+_122475397 1.888 ENSMUST00000075888.5
 Zic2
zinc finger protein of the cerebellum 2
chr10_+_97565436 1.673 ENSMUST00000038160.4
 Lum
lumican
chr17_+_23679363 1.638 ENSMUST00000024699.2
 Cldn6
claudin 6
chr2_-_38926217 1.563 ENSMUST00000076275.4
ENSMUST00000142130.1
 Nr6a1

nuclear receptor subfamily 6, group A, member 1

chr1_-_71653162 1.545 ENSMUST00000055226.6
 Fn1
fibronectin 1
chr4_-_117133953 1.500 ENSMUST00000076859.5
 Plk3
polo-like kinase 3
chr13_-_64274879 1.468 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr7_-_144939823 1.388 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr6_-_83033422 1.366 ENSMUST00000089651.5
 Dok1
docking protein 1
chr19_-_40271506 1.349 ENSMUST00000068439.6
 Pdlim1
PDZ and LIM domain 1 (elfin)
chr14_-_69503316 1.318 ENSMUST00000179116.2
 Gm21464
predicted gene, 21464
chrX_+_150547375 1.307 ENSMUST00000066337.6
ENSMUST00000112715.1
 Alas2

aminolevulinic acid synthase 2, erythroid

chr9_-_114564315 1.267 ENSMUST00000111816.2
 Trim71
tripartite motif-containing 71
chr17_-_34000257 1.253 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 548 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 3.1 GO:0034508 centromere complex assembly(GO:0034508)
0.1 2.9 GO:0042168 heme metabolic process(GO:0042168)
0.6 2.8 GO:0015671 oxygen transport(GO:0015671)
0.6 2.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 2.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 2.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 2.0 GO:0007530 sex determination(GO:0007530)
0.0 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.5 1.9 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 1.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 1.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.9 GO:0042407 cristae formation(GO:0042407)
0.6 1.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 1.7 GO:0032202 telomere assembly(GO:0032202)
0.3 1.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 239 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.4 GO:0005730 nucleolus(GO:0005730)
0.1 7.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.1 GO:0005643 nuclear pore(GO:0005643)
0.0 2.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.1 2.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 2.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.2 GO:0005795 Golgi stack(GO:0005795)
0.1 2.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.2 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 356 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 6.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 2.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.7 GO:0035198 miRNA binding(GO:0035198)
0.3 2.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.5 GO:0019843 rRNA binding(GO:0019843)
0.0 2.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 2.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 2.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 2.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 2.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.1 1.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 1.8 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4 1.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.7 GO:0043023 ribosomal large subunit binding(GO:0043023)