Motif ID: Atf4

Z-value: 1.292


Transcription factors associated with Atf4:

Gene SymbolEntrez IDGene Name
Atf4 ENSMUSG00000042406.7 Atf4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf4mm10_v2_chr15_+_80255184_802552630.484.4e-03Click!


Activity profile for motif Atf4.

activity profile for motif Atf4


Sorted Z-values histogram for motif Atf4

Sorted Z-values for motif Atf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 16.134 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_+_144896523 11.430 ENSMUST00000033389.5
 Fgf15
fibroblast growth factor 15
chr11_-_75422586 9.149 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr1_-_71653162 8.950 ENSMUST00000055226.6
 Fn1
fibronectin 1
chr11_-_75422524 7.727 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr13_-_53473074 7.597 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr4_+_46450892 6.641 ENSMUST00000102926.4
 Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr13_+_49682191 5.980 ENSMUST00000172254.1
 Iars
isoleucine-tRNA synthetase
chr8_+_75093591 4.550 ENSMUST00000005548.6
 Hmox1
heme oxygenase (decycling) 1
chr4_-_129189600 4.529 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chr19_-_12501996 4.378 ENSMUST00000045521.7
 Dtx4
deltex 4 homolog (Drosophila)
chr19_+_53140430 4.375 ENSMUST00000111741.2
 Add3
adducin 3 (gamma)
chr13_+_49682100 4.198 ENSMUST00000165316.1
ENSMUST00000047363.7
 Iars

isoleucine-tRNA synthetase

chr1_-_191183244 4.030 ENSMUST00000027941.8
 Atf3
activating transcription factor 3
chr12_-_104865076 3.978 ENSMUST00000109937.1
ENSMUST00000109936.1
 Clmn

calmin

chrX_+_106187100 3.729 ENSMUST00000081593.6
 Pgk1
phosphoglycerate kinase 1
chr9_-_71771535 3.634 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
 Cgnl1


cingulin-like 1


chr4_-_129189512 3.331 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr14_-_54870913 3.253 ENSMUST00000146642.1
 Homez
homeodomain leucine zipper-encoding gene
chr4_-_129189646 3.225 ENSMUST00000106059.1
 S100pbp
S100P binding protein
chr4_+_43957678 3.180 ENSMUST00000107855.1
 Glipr2
GLI pathogenesis-related 2
chr5_-_148399901 2.928 ENSMUST00000048116.8
 Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_18048784 2.830 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr6_-_83317589 2.686 ENSMUST00000005810.6
 Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr14_-_69284982 2.686 ENSMUST00000183882.1
ENSMUST00000037064.4
 Slc25a37

solute carrier family 25, member 37

chr4_+_117835387 2.635 ENSMUST00000169885.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_+_100320596 2.508 ENSMUST00000152521.1
 Eif1
eukaryotic translation initiation factor 1
chr2_+_163995503 2.334 ENSMUST00000131288.1
 Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr12_+_85599047 2.309 ENSMUST00000177587.1
 Jdp2
Jun dimerization protein 2
chr18_-_42262053 2.286 ENSMUST00000097590.3
 Lars
leucyl-tRNA synthetase
chr5_-_31179901 2.275 ENSMUST00000101411.2
ENSMUST00000140793.1
 Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr19_-_40588374 2.275 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
 Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr3_-_138143352 2.196 ENSMUST00000098580.2
 Mttp
microsomal triglyceride transfer protein
chr8_+_111033890 2.187 ENSMUST00000034441.7
 Aars
alanyl-tRNA synthetase
chr11_-_120643643 2.178 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
 Pycr1




pyrroline-5-carboxylate reductase 1




chr5_+_42067960 2.153 ENSMUST00000087332.4
 Gm16223
predicted gene 16223
chr6_+_55037988 2.117 ENSMUST00000003572.8
 Gars
glycyl-tRNA synthetase
chr1_-_170110491 2.110 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr12_+_85599388 2.092 ENSMUST00000050687.6
 Jdp2
Jun dimerization protein 2
chr12_-_108893197 2.087 ENSMUST00000161154.1
ENSMUST00000161410.1
 Wars

tryptophanyl-tRNA synthetase

chr9_-_44344159 2.071 ENSMUST00000077353.7
 Hmbs
hydroxymethylbilane synthase
chr3_+_138143888 2.052 ENSMUST00000161141.1
 Trmt10a
tRNA methyltransferase 10A
chr19_-_40588338 2.035 ENSMUST00000176939.1
 Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr13_-_118387224 2.011 ENSMUST00000022245.8
 Mrps30
mitochondrial ribosomal protein S30
chrX_+_103422010 1.960 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr8_-_92356103 1.945 ENSMUST00000034183.3
 4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr10_-_121626316 1.937 ENSMUST00000039810.7
 Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr7_-_126625676 1.923 ENSMUST00000032961.3
 Nupr1
nuclear protein transcription regulator 1
chr5_-_31180110 1.878 ENSMUST00000043161.6
ENSMUST00000088010.5
 Gtf3c2

general transcription factor IIIC, polypeptide 2, beta

chr7_-_143600049 1.869 ENSMUST00000105909.3
ENSMUST00000010899.7
 Cars

cysteinyl-tRNA synthetase

chr1_+_156838915 1.827 ENSMUST00000111720.1
 Angptl1
angiopoietin-like 1
chr19_-_15924928 1.824 ENSMUST00000025542.3
 Psat1
phosphoserine aminotransferase 1
chr3_+_138143429 1.765 ENSMUST00000040321.6
 Trmt10a
tRNA methyltransferase 10A
chr10_+_96616998 1.749 ENSMUST00000038377.7
 Btg1
B cell translocation gene 1, anti-proliferative
chr19_-_43524462 1.668 ENSMUST00000026196.7
 Got1
glutamate oxaloacetate transaminase 1, soluble
chr19_-_40588453 1.658 ENSMUST00000025979.6
 Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr2_-_18048347 1.637 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chr1_+_133131143 1.564 ENSMUST00000052529.3
 Ppp1r15b
protein phosphatase 1, regulatory (inhibitor) subunit 15b
chr4_+_129189760 1.559 ENSMUST00000106054.2
ENSMUST00000001365.2
 Yars

tyrosyl-tRNA synthetase

chr8_+_117157972 1.531 ENSMUST00000064488.4
ENSMUST00000162997.1
 Gan

giant axonal neuropathy

chr15_+_82147238 1.518 ENSMUST00000023100.6
 Srebf2
sterol regulatory element binding factor 2
chr3_+_138143483 1.340 ENSMUST00000162864.1
 Trmt10a
tRNA methyltransferase 10A
chr4_+_42735545 1.309 ENSMUST00000068158.3
 4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr5_+_145140362 1.297 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
 Bud31



BUD31 homolog (yeast)



chr2_-_3512746 1.275 ENSMUST00000027961.5
ENSMUST00000056700.7
 Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr17_-_34187219 1.217 ENSMUST00000173831.1
 Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr10_-_127311740 1.194 ENSMUST00000037290.5
ENSMUST00000171564.1
 Mars

methionine-tRNA synthetase

chr5_-_145140238 1.167 ENSMUST00000031627.8
 Pdap1
PDGFA associated protein 1
chr13_-_30545254 1.121 ENSMUST00000042834.3
 Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr1_-_78488846 1.113 ENSMUST00000068333.7
ENSMUST00000170217.1
 Farsb

phenylalanyl-tRNA synthetase, beta subunit

chr3_-_89998656 1.083 ENSMUST00000079724.4
 Hax1
HCLS1 associated X-1
chr18_-_64516547 1.079 ENSMUST00000025483.9
 Nars
asparaginyl-tRNA synthetase
chr8_+_123477859 1.021 ENSMUST00000001520.7
 Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr11_-_118290167 0.939 ENSMUST00000144153.1
 Usp36
ubiquitin specific peptidase 36
chr7_-_126502094 0.902 ENSMUST00000179818.1
 Atxn2l
ataxin 2-like
chr1_-_36709904 0.893 ENSMUST00000043951.3
 Actr1b
ARP1 actin-related protein 1B, centractin beta
chr5_+_93093428 0.865 ENSMUST00000074733.7
 Sept11
septin 11
chr17_+_34187545 0.823 ENSMUST00000170086.1
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr14_-_37135126 0.800 ENSMUST00000042564.9
 Ghitm
growth hormone inducible transmembrane protein
chr10_+_102158858 0.783 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
 Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr17_+_34187789 0.729 ENSMUST00000041633.8
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_126566364 0.728 ENSMUST00000032992.5
 Eif3c
eukaryotic translation initiation factor 3, subunit C
chr3_+_138143846 0.718 ENSMUST00000159481.1
 Trmt10a
tRNA methyltransferase 10A
chr7_+_138846579 0.654 ENSMUST00000155672.1
 Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr15_-_50889691 0.604 ENSMUST00000165201.2
ENSMUST00000184458.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr19_+_44203265 0.560 ENSMUST00000026220.5
 Scd3
stearoyl-coenzyme A desaturase 3
chr11_-_118290188 0.539 ENSMUST00000106296.2
ENSMUST00000092382.3
 Usp36

ubiquitin specific peptidase 36

chr11_-_98400453 0.508 ENSMUST00000090827.5
 Pgap3
post-GPI attachment to proteins 3
chr10_-_127522428 0.507 ENSMUST00000026470.4
 Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr15_+_99393219 0.388 ENSMUST00000159209.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr10_-_68278713 0.370 ENSMUST00000020106.7
 Arid5b
AT rich interactive domain 5B (MRF1-like)
chr4_-_108833608 0.367 ENSMUST00000102742.4
 Btf3l4
basic transcription factor 3-like 4
chr1_+_134455524 0.358 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
 Klhl12


kelch-like 12


chr7_-_126502312 0.347 ENSMUST00000166682.2
 Atxn2l
ataxin 2-like
chr4_+_127021311 0.340 ENSMUST00000030623.7
 Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr15_-_98953541 0.327 ENSMUST00000097014.5
 Tuba1a
tubulin, alpha 1A
chr3_+_138143799 0.258 ENSMUST00000159622.1
 Trmt10a
tRNA methyltransferase 10A
chr14_+_63436394 0.206 ENSMUST00000121288.1
 Fam167a
family with sequence similarity 167, member A
chr15_+_99393610 0.186 ENSMUST00000159531.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr19_-_4793851 0.144 ENSMUST00000178615.1
ENSMUST00000179189.1
ENSMUST00000164376.2
ENSMUST00000164209.2
ENSMUST00000180248.1
 Rbm4




RNA binding motif protein 4




chr8_+_94386486 0.132 ENSMUST00000034220.7
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_-_98400393 0.126 ENSMUST00000128897.1
 Pgap3
post-GPI attachment to proteins 3
chr3_+_89715016 0.088 ENSMUST00000098924.2
 Adar
adenosine deaminase, RNA-specific
chr10_+_121739915 0.069 ENSMUST00000065600.7
ENSMUST00000136432.1
 BC048403

cDNA sequence BC048403

chr10_+_80141457 0.037 ENSMUST00000105367.1
 Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr15_-_83510861 0.027 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
 Ttll1


tubulin tyrosine ligase-like 1


chr5_-_90223923 0.023 ENSMUST00000118816.1
ENSMUST00000048363.7
 Cox18

cytochrome c oxidase assembly protein 18


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
3.0 9.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
2.9 11.4 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
2.7 16.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.5 7.6 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
2.3 4.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
2.0 6.0 GO:0006592 ornithine biosynthetic process(GO:0006592)
1.9 16.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.0 4.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.9 2.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7 2.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.7 2.1 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.7 2.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6 1.9 GO:0051031 tRNA transport(GO:0051031)
0.6 1.7 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.5 2.9 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.5 2.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 2.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.4 1.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 2.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 1.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 1.6 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.4 1.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.4 2.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.3 1.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.3 1.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 2.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 1.6 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2 6.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.9 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 2.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 4.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.2 6.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 2.5 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 4.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 4.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.5 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 3.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.0 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 3.1 GO:0006094 gluconeogenesis(GO:0006094)
0.0 2.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 1.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055) circadian regulation of translation(GO:0097167)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.2 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.8 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.0 1.2 GO:0019882 antigen processing and presentation(GO:0019882)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0005577 fibrinogen complex(GO:0005577)
1.2 16.9 GO:0043203 axon hillock(GO:0043203)
0.5 4.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.0 GO:0005745 m-AAA complex(GO:0005745)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 3.6 GO:0016459 myosin complex(GO:0016459)
0.1 4.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 4.5 GO:0005901 caveola(GO:0005901)
0.0 2.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0005643 nuclear pore(GO:0005643)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 3.3 GO:0005840 ribosome(GO:0005840)
0.0 3.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
2.4 9.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.5 9.0 GO:0045340 mercury ion binding(GO:0045340)
1.1 4.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 2.7 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.7 2.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.7 2.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.6 1.7 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.5 2.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 1.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.5 11.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 2.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.9 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.4 1.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 1.6 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.4 16.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 1.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.3 2.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 2.3 GO:0050815 phosphoserine binding(GO:0050815)
0.2 2.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 7.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.2 8.1 GO:0000049 tRNA binding(GO:0000049)
0.2 0.5 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 34.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 0.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 11.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.4 GO:0008483 transaminase activity(GO:0008483)
0.1 1.2 GO:0070628 proteasome binding(GO:0070628)
0.1 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 1.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 3.6 GO:0003774 motor activity(GO:0003774)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 8.4 GO:0003779 actin binding(GO:0003779)
0.0 4.4 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)