Motif ID: Atf5

Z-value: 1.065


Transcription factors associated with Atf5:

Gene SymbolEntrez IDGene Name
Atf5 ENSMUSG00000038539.8 Atf5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44816586_448166580.707.0e-06Click!


Activity profile for motif Atf5.

activity profile for motif Atf5


Sorted Z-values histogram for motif Atf5

Sorted Z-values for motif Atf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 113 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_51621830 9.541 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chrX_+_166344692 8.239 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr1_-_158356258 7.705 ENSMUST00000004133.8
 Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr14_+_54936456 7.343 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr2_+_124610573 6.826 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr8_+_54954728 6.584 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr4_-_82705735 6.516 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr18_-_23041641 5.885 ENSMUST00000097651.3
 Nol4
nucleolar protein 4
chr15_-_79164477 5.646 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chrX_+_41401304 5.630 ENSMUST00000076349.5
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_-_22805994 5.443 ENSMUST00000097808.4
 Rims1
regulating synaptic membrane exocytosis 1
chr19_-_46327121 5.317 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing

chr12_+_89812467 5.159 ENSMUST00000110133.2
ENSMUST00000110130.2
 Nrxn3

neurexin III

chr7_-_4996044 4.715 ENSMUST00000162502.1
 Zfp579
zinc finger protein 579
chr4_-_91376433 4.659 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
 Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr4_-_8239034 4.614 ENSMUST00000066674.7
 Car8
carbonic anhydrase 8
chr16_+_38089001 4.470 ENSMUST00000023507.6
 Gsk3b
glycogen synthase kinase 3 beta
chrX_+_41401128 4.432 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr19_-_42202150 4.185 ENSMUST00000018966.7
 Sfrp5
secreted frizzled-related sequence protein 5
chr18_+_64254359 4.119 ENSMUST00000025477.7
 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 10.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.6 9.5 GO:0001504 neurotransmitter uptake(GO:0001504)
1.2 8.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 7.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.6 7.1 GO:0048484 enteric nervous system development(GO:0048484)
0.2 6.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 6.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.6 6.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 6.2 GO:0060976 coronary vasculature development(GO:0060976)
0.7 5.5 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
1.8 5.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.4 5.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 5.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 5.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 4.6 GO:0006730 one-carbon metabolic process(GO:0006730)
1.5 4.5 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 4.4 GO:0048813 dendrite morphogenesis(GO:0048813)
1.4 4.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.0 4.1 GO:1990743 protein sialylation(GO:1990743)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 13.4 GO:0042734 presynaptic membrane(GO:0042734)
1.2 12.9 GO:0043083 synaptic cleft(GO:0043083)
0.0 10.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 9.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 6.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 6.2 GO:0044295 axonal growth cone(GO:0044295)
0.7 5.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 5.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.1 5.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 4.5 GO:1990909 Wnt signalosome(GO:1990909)
0.3 4.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 3.2 GO:0034399 nuclear periphery(GO:0034399)
0.1 3.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 2.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.7 GO:0043235 receptor complex(GO:0043235)
0.1 2.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.5 GO:0036126 sperm flagellum(GO:0036126)
0.2 2.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.2 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 12.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 9.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.2 8.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 7.8 GO:0005125 cytokine activity(GO:0005125)
0.4 7.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 7.5 GO:0005262 calcium channel activity(GO:0005262)
0.2 6.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 6.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 6.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.9 5.5 GO:0070699 type II activin receptor binding(GO:0070699)
1.8 5.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 5.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 4.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 4.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.4 4.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.7 4.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 4.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 3.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 3.1 GO:0030276 clathrin binding(GO:0030276)
0.1 2.9 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)