Motif ID: Atf6

Z-value: 1.092


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.232.0e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 4.948 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr8_-_70487314 4.410 ENSMUST00000045286.7
 Tmem59l
transmembrane protein 59-like
chr7_+_126950518 3.893 ENSMUST00000106335.1
ENSMUST00000146017.1
 Sez6l2

seizure related 6 homolog like 2

chr5_+_134986191 3.751 ENSMUST00000094245.2
 Cldn3
claudin 3
chr7_+_126950837 3.671 ENSMUST00000106332.1
 Sez6l2
seizure related 6 homolog like 2
chr7_+_126950687 3.666 ENSMUST00000106333.1
 Sez6l2
seizure related 6 homolog like 2
chr10_+_29211637 3.555 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr16_-_23988852 3.294 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr3_+_123267445 3.245 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chrY_-_1245753 3.176 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr18_-_31447383 3.147 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr5_-_136170634 3.083 ENSMUST00000041048.1
 Orai2
ORAI calcium release-activated calcium modulator 2
chr8_-_70700070 2.599 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr13_-_36734450 2.452 ENSMUST00000037623.8
 Nrn1
neuritin 1
chr2_+_55437100 2.289 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr11_+_84525669 2.284 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr17_+_46297917 2.217 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr11_+_69991061 2.192 ENSMUST00000018711.8
 Gabarap
gamma-aminobutyric acid receptor associated protein
chr4_+_43406435 2.105 ENSMUST00000098106.2
ENSMUST00000139198.1
 Rusc2

RUN and SH3 domain containing 2

chr8_+_34807287 2.090 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 12.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.9 7.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 5.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 4.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.4 3.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 3.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 3.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.1 3.3 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 3.3 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 3.2 GO:0060416 response to growth hormone(GO:0060416)
0.4 3.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 3.1 GO:0090166 Golgi disassembly(GO:0090166)
0.2 2.5 GO:0045176 apical protein localization(GO:0045176)
0.0 2.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.8 2.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 2.4 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 2.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 2.2 GO:1990138 neuron projection extension(GO:1990138)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 5.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 3.9 GO:0000421 autophagosome membrane(GO:0000421)
0.2 3.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.8 GO:0030426 growth cone(GO:0030426)
0.1 3.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.4 GO:0043209 myelin sheath(GO:0043209)
0.1 3.2 GO:0043034 costamere(GO:0043034)
0.1 3.0 GO:0031201 SNARE complex(GO:0031201)
0.3 2.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.6 GO:0005657 replication fork(GO:0005657)
0.1 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.4 GO:0097060 synaptic membrane(GO:0097060)
0.0 2.3 GO:0030315 T-tubule(GO:0030315)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.1 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.5 GO:0005827 polar microtubule(GO:0005827)
0.2 1.4 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 7.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 4.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 3.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 3.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 3.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 3.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.6 2.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 2.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 2.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.2 GO:0050811 GABA receptor binding(GO:0050811)
0.3 2.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 2.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.5 1.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)