Motif ID: Atf7_E4f1

Z-value: 1.071

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E4f1mm10_v2_chr17_-_24455265_24455345-0.654.5e-05Click!
Atf7mm10_v2_chr15_-_102529025_102529025-0.621.2e-04Click!


Activity profile for motif Atf7_E4f1.

activity profile for motif Atf7_E4f1


Sorted Z-values histogram for motif Atf7_E4f1

Sorted Z-values for motif Atf7_E4f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 6.149 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr9_-_20976762 5.649 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr3_+_67374116 5.566 ENSMUST00000061322.8
 Mlf1
myeloid leukemia factor 1
chr3_+_67374091 5.091 ENSMUST00000077916.5
 Mlf1
myeloid leukemia factor 1
chr4_+_141301228 4.449 ENSMUST00000006614.2
 Epha2
Eph receptor A2
chr4_+_111720187 4.060 ENSMUST00000084354.3
 Spata6
spermatogenesis associated 6
chr5_-_106458440 3.769 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr8_+_116921735 3.748 ENSMUST00000034205.4
 Cenpn
centromere protein N
chr7_-_144939823 3.537 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr3_-_36571952 3.297 ENSMUST00000029270.3
 Ccna2
cyclin A2
chr1_+_74791516 3.255 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr17_+_23679363 3.057 ENSMUST00000024699.2
 Cldn6
claudin 6
chr17_-_31277327 3.046 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr12_+_112644828 2.883 ENSMUST00000021728.4
ENSMUST00000109755.3
 Siva1

SIVA1, apoptosis-inducing factor

chr12_-_69159109 2.836 ENSMUST00000037023.8
 Rps29
ribosomal protein S29
chr17_+_36958623 2.829 ENSMUST00000173814.1
 Znrd1as
Znrd1 antisense
chr9_-_96478660 2.738 ENSMUST00000057500.4
 Rnf7
ring finger protein 7
chr8_+_45885479 2.666 ENSMUST00000034053.5
 Pdlim3
PDZ and LIM domain 3
chr13_+_8885501 2.611 ENSMUST00000169314.2
 Idi1
isopentenyl-diphosphate delta isomerase
chr17_+_36958571 2.610 ENSMUST00000040177.6
 Znrd1as
Znrd1 antisense

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 214 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.0 GO:0006412 translation(GO:0006412)
1.0 7.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.7 6.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.0 6.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 6.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.5 6.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 6.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 5.8 GO:0034508 centromere complex assembly(GO:0034508)
1.4 5.7 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
1.9 5.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 5.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4 5.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 4.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 4.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.8 4.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 4.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
1.5 4.4 GO:0014028 notochord formation(GO:0014028)
0.0 4.3 GO:0006364 rRNA processing(GO:0006364)
0.5 4.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 4.1 GO:0044458 motile cilium assembly(GO:0044458)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.8 GO:0031514 motile cilium(GO:0031514)
0.3 12.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 11.4 GO:0000776 kinetochore(GO:0000776)
0.1 10.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 7.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 7.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.7 6.7 GO:0030008 TRAPP complex(GO:0030008)
0.6 6.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.9 5.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.7 5.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 5.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 4.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 3.7 GO:0016589 NURF complex(GO:0016589)
0.1 3.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 3.3 GO:0001940 male pronucleus(GO:0001940)
0.4 3.3 GO:0098536 deuterosome(GO:0098536)
0.1 3.3 GO:0005669 transcription factor TFIID complex(GO:0005669)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.0 GO:0044822 poly(A) RNA binding(GO:0044822)
0.1 12.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 7.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 6.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 6.1 GO:0017070 U6 snRNA binding(GO:0017070)
1.0 6.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 5.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 5.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.7 5.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 4.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 4.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.8 4.1 GO:0032027 myosin light chain binding(GO:0032027)
0.5 4.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 3.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.8 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 3.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.1 GO:0048487 beta-tubulin binding(GO:0048487)