Motif ID: Atoh1_Bhlhe23

Z-value: 0.694

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_1807767490.566.3e-04Click!


Activity profile for motif Atoh1_Bhlhe23.

activity profile for motif Atoh1_Bhlhe23


Sorted Z-values histogram for motif Atoh1_Bhlhe23

Sorted Z-values for motif Atoh1_Bhlhe23



Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Showing 1 to 20 of 97 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_177444653 8.911 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr2_-_79456750 6.408 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr11_-_98329641 5.426 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr11_+_58954675 5.407 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr9_-_21918089 4.509 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr2_-_29253001 4.061 ENSMUST00000071201.4
 Ntng2
netrin G2
chr3_-_84259812 3.468 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr4_-_110292719 3.147 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_-_91191733 3.102 ENSMUST00000069511.6
 Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr9_+_72985568 2.679 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr5_-_66618772 2.468 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
 Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr1_+_177445660 2.466 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr9_+_72985504 2.426 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr6_+_112273758 2.277 ENSMUST00000032376.5
 Lmcd1
LIM and cysteine-rich domains 1
chr17_-_6449571 2.254 ENSMUST00000180035.1
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_-_150392719 2.243 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr10_+_69706326 2.193 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr2_+_62046623 2.181 ENSMUST00000112480.2
 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_62046580 2.155 ENSMUST00000054484.8
 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr5_-_144223516 2.077 ENSMUST00000085701.6
 Tecpr1
tectonin beta-propeller repeat containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.4 GO:0021766 hippocampus development(GO:0021766)
1.6 6.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.3 5.9 GO:0021860 pyramidal neuron development(GO:0021860)
1.8 5.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 5.4 GO:0070914 UV-damage excision repair(GO:0070914)
1.3 5.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 4.9 GO:0007050 cell cycle arrest(GO:0007050)
0.9 4.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 3.5 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.3 3.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 3.1 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.2 2.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 2.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.1 GO:0097352 autophagosome maturation(GO:0097352)
0.6 1.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 1.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 1.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.4 1.5 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 1.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.4 GO:0045171 intercellular bridge(GO:0045171)
1.2 5.9 GO:0097441 basilar dendrite(GO:0097441)
0.2 5.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 5.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 4.5 GO:0042588 zymogen granule(GO:0042588)
0.1 4.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 3.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.1 GO:0031430 M band(GO:0031430)
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.4 GO:0070938 contractile ring(GO:0070938)
0.1 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.8 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 10.7 GO:0070888 E-box binding(GO:0070888)
0.1 6.0 GO:0030674 protein binding, bridging(GO:0030674)
0.3 5.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 4.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 4.5 GO:0031489 myosin V binding(GO:0031489)
0.1 3.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.5 GO:0017022 myosin binding(GO:0017022)
0.2 3.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 2.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.4 GO:0031072 heat shock protein binding(GO:0031072)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.3 GO:0032036 myosin heavy chain binding(GO:0032036)