Motif ID: Barhl2

Z-value: 1.250


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.502.8e-03Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_71663665 6.845 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr5_-_28467093 5.989 ENSMUST00000002708.3
Shh
sonic hedgehog
chr19_+_25406661 5.896 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr18_+_61045139 5.488 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr16_-_22439719 5.429 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr5_-_37824580 4.978 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr6_+_63255971 4.517 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr19_-_6969746 4.356 ENSMUST00000025912.8
Plcb3
phospholipase C, beta 3
chr17_-_49564262 4.277 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr16_-_22439570 4.272 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr5_+_110839973 4.003 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr7_+_24370255 3.915 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_73821857 3.798 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr18_-_80986578 3.595 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr17_+_35439155 3.548 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr4_-_9643638 3.512 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr6_+_125552948 3.483 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_+_85832551 3.211 ENSMUST00000000095.6
Tbx2
T-box 2
chr1_+_153899937 3.058 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr1_-_163725123 2.949 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr7_+_128246953 2.882 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr7_+_128246812 2.859 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr18_+_4993795 2.853 ENSMUST00000153016.1
Svil
supervillin
chr2_+_163225363 2.841 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr3_-_154328634 2.813 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr4_+_154960915 2.798 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr11_-_20332689 2.634 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_-_20332654 2.468 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_146502099 2.434 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr6_-_95718800 2.403 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr2_+_59612034 2.292 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr1_-_93343482 2.257 ENSMUST00000128253.1
Pask
PAS domain containing serine/threonine kinase
chr1_-_153900198 2.219 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr11_+_78261717 2.148 ENSMUST00000010421.6
2610507B11Rik
RIKEN cDNA 2610507B11 gene
chr11_+_112782182 2.031 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr19_-_29648355 1.959 ENSMUST00000159692.1
Ermp1
endoplasmic reticulum metallopeptidase 1
chr10_+_58394381 1.873 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr17_+_79614900 1.867 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr7_+_27486910 1.857 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr3_-_27153782 1.830 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chrX_+_95711641 1.823 ENSMUST00000150123.1
Zc3h12b
zinc finger CCCH-type containing 12B
chr7_+_127841752 1.779 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr2_-_84715160 1.722 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr4_+_132768325 1.706 ENSMUST00000102561.4
Rpa2
replication protein A2
chr17_-_25727364 1.603 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr5_-_134946917 1.582 ENSMUST00000051401.2
Cldn4
claudin 4
chr7_+_79660196 1.573 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr3_-_110143937 1.563 ENSMUST00000051253.3
Ntng1
netrin G1
chr11_+_62820469 1.561 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr2_-_58052832 1.560 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr10_+_58394361 1.549 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_127841817 1.511 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr12_+_78748947 1.474 ENSMUST00000082024.5
Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr3_-_27153844 1.464 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr8_+_94214567 1.442 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr2_-_127133909 1.432 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr2_+_181319806 1.394 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr5_+_33658123 1.328 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr6_-_47813512 1.318 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr4_-_49597425 1.306 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr2_-_129699833 1.291 ENSMUST00000028883.5
Pdyn
prodynorphin
chr6_-_34317442 1.290 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr11_-_120572822 1.210 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr8_-_90908415 1.205 ENSMUST00000098517.1
Gm6658
predicted gene 6658
chrX_+_169879596 1.183 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr2_+_181319714 1.148 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr2_+_118814237 1.136 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr12_-_34528844 1.123 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr1_+_50927511 1.120 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_+_165788681 1.106 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr15_-_80014808 1.098 ENSMUST00000000500.6
Pdgfb
platelet derived growth factor, B polypeptide
chr5_+_65131184 1.083 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr18_+_61639542 1.081 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr1_+_105990652 1.078 ENSMUST00000118196.1
Zcchc2
zinc finger, CCHC domain containing 2
chr17_-_34287770 1.050 ENSMUST00000174751.1
ENSMUST00000040655.6
H2-Aa

histocompatibility 2, class II antigen A, alpha

chr3_-_27153861 1.013 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr8_+_57511833 0.980 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr7_+_100495987 0.949 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr10_+_88459569 0.943 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr1_+_105990384 0.831 ENSMUST00000119166.1
Zcchc2
zinc finger, CCHC domain containing 2
chr11_-_120573253 0.821 ENSMUST00000026122.4
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr15_+_99074968 0.813 ENSMUST00000039665.6
Troap
trophinin associated protein
chr1_+_165788746 0.743 ENSMUST00000161559.2
Cd247
CD247 antigen
chr14_-_99099701 0.707 ENSMUST00000042471.9
Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr13_-_47106176 0.671 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr7_-_19715395 0.625 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr12_+_72441933 0.611 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr5_+_145204523 0.610 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr3_-_49757257 0.603 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chrX_-_59166080 0.596 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr15_-_93519499 0.558 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr19_+_8617991 0.554 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr4_-_41275091 0.551 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr7_+_43444104 0.521 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr18_-_78206408 0.470 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr4_-_43000451 0.459 ENSMUST00000030164.7
Vcp
valosin containing protein
chr12_+_72441852 0.459 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr17_-_47502276 0.420 ENSMUST00000067103.2
Taf8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq
chr3_+_96629919 0.410 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr14_-_88471396 0.382 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr2_-_120539852 0.370 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr15_-_100424092 0.370 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr15_-_100425050 0.345 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr15_-_100424208 0.332 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_-_12796108 0.298 ENSMUST00000038627.8
Zfp91
zinc finger protein 91
chr2_-_18048347 0.244 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr7_-_127376028 0.222 ENSMUST00000067425.4
Zfp747
zinc finger protein 747
chrX_+_82948861 0.199 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr5_-_110839757 0.178 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr7_-_90475971 0.149 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr9_-_13826946 0.127 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr16_+_3872368 0.109 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_+_91250311 0.061 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
Ube2f


ubiquitin-conjugating enzyme E2F (putative)


chr4_-_58553553 0.052 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr6_-_101377897 0.036 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr2_+_9882622 0.015 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
2.0 6.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
2.0 5.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.9 9.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.7 5.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.2 3.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1 3.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
1.1 3.2 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
1.0 3.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
1.0 4.0 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.9 3.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.8 5.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.8 3.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.7 5.1 GO:0015808 L-alanine transport(GO:0015808)
0.7 2.8 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.7 2.0 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.6 2.5 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.4 1.3 GO:1903334 positive regulation of protein folding(GO:1903334)
0.4 1.3 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.4 3.8 GO:0050957 equilibrioception(GO:0050957)
0.4 2.0 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 2.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 4.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 0.9 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.3 5.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.3 0.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 3.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.3 2.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.3 2.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.0 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 1.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 1.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314)
0.2 1.6 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.2 0.7 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 0.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.5 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 2.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 4.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 1.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 3.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 3.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.5 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 4.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 3.5 GO:0030168 platelet activation(GO:0030168)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.0 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833) maintenance of protein location in nucleus(GO:0051457)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 6.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.9 GO:0030308 negative regulation of cell growth(GO:0030308)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0097149 centralspindlin complex(GO:0097149)
0.7 3.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.7 3.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 4.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.5 2.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.5 2.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.5 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 2.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3 1.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 0.9 GO:0000802 transverse filament(GO:0000802)
0.3 3.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.4 GO:0000796 condensin complex(GO:0000796)
0.2 1.0 GO:0070826 paraferritin complex(GO:0070826)
0.2 1.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.6 GO:0033269 internode region of axon(GO:0033269)
0.2 3.1 GO:0097386 glial cell projection(GO:0097386)
0.2 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 3.8 GO:0032420 stereocilium(GO:0032420)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 3.9 GO:0005882 intermediate filament(GO:0005882)
0.1 5.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.6 GO:0016605 PML body(GO:0016605)
0.1 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 9.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.4 GO:0042383 sarcolemma(GO:0042383)
0.0 11.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 9.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0008502 melatonin receptor activity(GO:0008502)
1.2 6.0 GO:0005113 patched binding(GO:0005113)
1.1 5.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.0 3.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 3.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 3.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.8 2.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 5.7 GO:0048495 Roundabout binding(GO:0048495)
0.6 5.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.5 1.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.4 2.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.4 3.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 3.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.7 GO:0001515 opioid peptide activity(GO:0001515)
0.2 4.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.4 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.2 1.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0015265 urea channel activity(GO:0015265)
0.1 0.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 8.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 5.0 GO:0002039 p53 binding(GO:0002039)
0.1 3.6 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 5.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 3.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 6.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 4.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 5.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 4.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)