Motif ID: Barhl2

Z-value: 1.250


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.502.8e-03Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 116 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_71663665 6.845 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr5_-_28467093 5.989 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr19_+_25406661 5.896 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr18_+_61045139 5.488 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr16_-_22439719 5.429 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr5_-_37824580 4.978 ENSMUST00000063116.9
 Msx1
msh homeobox 1
chr6_+_63255971 4.517 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr19_-_6969746 4.356 ENSMUST00000025912.8
 Plcb3
phospholipase C, beta 3
chr17_-_49564262 4.277 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr16_-_22439570 4.272 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr5_+_110839973 4.003 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr7_+_24370255 3.915 ENSMUST00000171904.1
 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_73821857 3.798 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
 Pcdh15



















protocadherin 15



















chr18_-_80986578 3.595 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr17_+_35439155 3.548 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
 H2-Q7



histocompatibility 2, Q region locus 7



chr4_-_9643638 3.512 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr6_+_125552948 3.483 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr11_+_85832551 3.211 ENSMUST00000000095.6
 Tbx2
T-box 2
chr1_+_153899937 3.058 ENSMUST00000086199.5
 Glul
glutamate-ammonia ligase (glutamine synthetase)
chr1_-_163725123 2.949 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 9.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 6.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
2.2 6.6 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
2.0 6.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
2.0 5.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.8 5.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 5.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.7 5.1 GO:0015808 L-alanine transport(GO:0015808)
1.7 5.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 4.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 4.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 4.2 GO:0007368 determination of left/right symmetry(GO:0007368)
1.0 4.0 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.8 3.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 3.8 GO:0050957 equilibrioception(GO:0050957)
0.3 3.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
1.2 3.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 3.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 3.5 GO:0030168 platelet activation(GO:0030168)
0.9 3.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 9.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 9.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 5.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.6 GO:0016605 PML body(GO:0016605)
0.6 4.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 4.4 GO:0042383 sarcolemma(GO:0042383)
0.9 4.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 3.9 GO:0005882 intermediate filament(GO:0005882)
0.1 3.8 GO:0032420 stereocilium(GO:0032420)
0.7 3.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.7 3.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 3.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 3.1 GO:0097386 glial cell projection(GO:0097386)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.5 2.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 2.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.5 2.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.5 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.6 GO:0017048 Rho GTPase binding(GO:0017048)
2.3 6.8 GO:0008502 melatonin receptor activity(GO:0008502)
1.2 6.0 GO:0005113 patched binding(GO:0005113)
0.0 6.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.9 GO:0008013 beta-catenin binding(GO:0008013)
0.7 5.7 GO:0048495 Roundabout binding(GO:0048495)
1.1 5.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 5.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.6 5.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 5.0 GO:0002039 p53 binding(GO:0002039)
0.2 4.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 4.4 GO:0051015 actin filament binding(GO:0051015)
0.0 4.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 4.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
1.0 3.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 3.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 3.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.4 3.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 3.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 3.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)