Motif ID: Bbx

Z-value: 0.295


Transcription factors associated with Bbx:

Gene SymbolEntrez IDGene Name
Bbx ENSMUSG00000022641.9 Bbx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50432340_504324090.522.0e-03Click!


Activity profile for motif Bbx.

activity profile for motif Bbx


Sorted Z-values histogram for motif Bbx

Sorted Z-values for motif Bbx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bbx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_52530827 1.603 ENSMUST00000057442.6
 Diras2
DIRAS family, GTP-binding RAS-like 2
chr15_+_21111452 1.389 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr5_-_146585239 1.325 ENSMUST00000036211.6
 Gpr12
G-protein coupled receptor 12
chr18_+_37421418 1.033 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chr16_+_20693263 0.981 ENSMUST00000149543.1
ENSMUST00000118919.1
 Fam131a

family with sequence similarity 131, member A

chr10_-_86022325 0.958 ENSMUST00000181665.1
 A230060F14Rik
RIKEN cDNA A230060F14 gene
chr8_+_45658666 0.714 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
 Sorbs2


sorbin and SH3 domain containing 2


chrX_+_159708593 0.661 ENSMUST00000080394.6
 Sh3kbp1
SH3-domain kinase binding protein 1
chr10_+_86021961 0.623 ENSMUST00000130320.1
 Fbxo7
F-box protein 7
chr13_+_49608030 0.607 ENSMUST00000021822.5
 Ogn
osteoglycin
chr8_+_45658731 0.600 ENSMUST00000143820.1
ENSMUST00000132139.1
 Sorbs2

sorbin and SH3 domain containing 2

chr1_+_180111339 0.539 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr2_+_136892168 0.524 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chrX_-_107816238 0.516 ENSMUST00000120722.1
 2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr8_+_45658273 0.477 ENSMUST00000153798.1
 Sorbs2
sorbin and SH3 domain containing 2
chr11_+_105146893 0.365 ENSMUST00000100338.1
 Gm10842
predicted gene 10842
chr8_-_41054771 0.320 ENSMUST00000093534.4
 Mtus1
mitochondrial tumor suppressor 1
chrX_-_150814265 0.245 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
 Maged2


melanoma antigen, family D, 2


chr3_+_16183177 0.238 ENSMUST00000108345.2
ENSMUST00000108346.2
 Ythdf3

YTH domain family 3

chr10_+_84622365 0.221 ENSMUST00000077175.5
 Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chrX_+_140367494 0.202 ENSMUST00000141660.1
 Frmpd3
FERM and PDZ domain containing 3
chr7_+_127800604 0.185 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr12_+_103388656 0.131 ENSMUST00000101094.2
ENSMUST00000021620.6
 Otub2

OTU domain, ubiquitin aldehyde binding 2

chr2_-_152830615 0.119 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
 Bcl2l1



BCL2-like 1



chr7_-_127708886 0.008 ENSMUST00000061468.8
 Bcl7c
B cell CLL/lymphoma 7C
chr5_-_108675569 0.007 ENSMUST00000051757.7
 Slc26a1
solute carrier family 26 (sulfate transporter), member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)