Motif ID: Bcl6

Z-value: 0.972


Transcription factors associated with Bcl6:

Gene SymbolEntrez IDGene Name
Bcl6 ENSMUSG00000022508.5 Bcl6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6mm10_v2_chr16_-_23988852_239888520.671.9e-05Click!


Activity profile for motif Bcl6.

activity profile for motif Bcl6


Sorted Z-values histogram for motif Bcl6

Sorted Z-values for motif Bcl6



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6

PNG image of the network

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Top targets:


Showing 1 to 20 of 188 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 8.395 ENSMUST00000107377.3
 Tnc
tenascin C
chr3_-_152982240 5.072 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr15_-_54919961 4.797 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr3_-_80802789 4.562 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr6_-_5496296 3.790 ENSMUST00000019721.4
 Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr6_+_115134899 3.761 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr15_-_54920115 3.743 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_-_8710409 3.648 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_101245996 3.502 ENSMUST00000129680.1
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_+_100015817 3.463 ENSMUST00000130190.1
ENSMUST00000020129.7
 Kitl

kit ligand

chr15_-_8710734 3.446 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_124569696 3.329 ENSMUST00000063278.6
 Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_-_36784924 3.197 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
 Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr10_+_86300372 3.059 ENSMUST00000020234.7
 Timp3
tissue inhibitor of metalloproteinase 3
chr4_+_144892813 3.049 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr12_+_88953399 2.896 ENSMUST00000057634.7
 Nrxn3
neurexin III
chrX_-_61185558 2.880 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr7_+_129257027 2.874 ENSMUST00000094018.4
 Ppapdc1a
phosphatidic acid phosphatase type 2 domain containing 1A
chr16_-_36784784 2.829 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr1_-_169747634 2.674 ENSMUST00000027991.5
ENSMUST00000111357.1
 Rgs4

regulator of G-protein signaling 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 8.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
2.1 8.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.7 7.3 GO:0042572 retinol metabolic process(GO:0042572)
1.8 7.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.5 6.0 GO:0042938 dipeptide transport(GO:0042938)
0.4 5.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 4.7 GO:0032264 IMP salvage(GO:0032264)
0.2 4.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.3 3.9 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 3.9 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.9 3.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 3.8 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.9 3.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.4 3.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.7 3.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.8 3.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 3.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 2.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 2.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.4 2.5 GO:0007021 tubulin complex assembly(GO:0007021)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.5 8.7 GO:0005614 interstitial matrix(GO:0005614)
0.4 7.1 GO:0043205 fibril(GO:0043205)
0.2 7.0 GO:0060077 inhibitory synapse(GO:0060077)
0.2 4.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 4.6 GO:0072562 blood microparticle(GO:0072562)
0.1 3.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 2.9 GO:0042734 presynaptic membrane(GO:0042734)
0.8 2.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.1 GO:0097228 sperm principal piece(GO:0097228)
0.2 2.0 GO:0044292 dendrite terminus(GO:0044292)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 1.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.6 GO:0005776 autophagosome(GO:0005776)
0.1 1.1 GO:0005915 zonula adherens(GO:0005915)
0.1 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 1.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 8.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.4 8.4 GO:0045545 syndecan binding(GO:0045545)
1.0 7.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.4 7.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.2 6.0 GO:0042895 antibiotic transporter activity(GO:0042895)
0.7 5.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.7 4.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8 4.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.9 3.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 3.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 3.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 3.3 GO:0048018 receptor agonist activity(GO:0048018)
0.2 3.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 3.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 2.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.4 2.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.7 GO:0015026 coreceptor activity(GO:0015026)