Motif ID: Bcl6b

Z-value: 0.559


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.672.0e-05Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 6.730 ENSMUST00000107377.3
 Tnc
tenascin C
chr16_-_74411292 3.796 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 3.114 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr3_+_55242526 2.845 ENSMUST00000054237.7
ENSMUST00000167204.1
 Dclk1

doublecortin-like kinase 1

chr9_+_40269430 2.845 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr19_-_5797410 2.574 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr8_+_13907748 2.208 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chrX_+_151344171 2.145 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr3_-_96240317 1.986 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr13_-_98815408 1.853 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr1_-_173942445 1.830 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr10_+_57794335 1.808 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr2_-_65567465 1.763 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_-_95417099 1.762 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr2_-_65567505 1.643 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_+_119594288 1.486 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr10_+_81633694 1.319 ENSMUST00000140345.1
ENSMUST00000126323.1
 Ankrd24

ankyrin repeat domain 24

chr9_-_112232449 1.286 ENSMUST00000035085.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr10_-_95416850 1.205 ENSMUST00000020215.9
 Socs2
suppressor of cytokine signaling 2
chr6_+_149309391 1.176 ENSMUST00000130664.1
ENSMUST00000046689.6
 2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr5_-_123140135 1.152 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr6_+_149309444 1.145 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr18_+_37320374 1.129 ENSMUST00000078271.2
 Pcdhb5
protocadherin beta 5
chr11_+_70764209 1.046 ENSMUST00000060444.5
 Zfp3
zinc finger protein 3
chr5_-_150665560 1.013 ENSMUST00000118316.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr5_-_150665315 0.924 ENSMUST00000141857.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr12_-_40134175 0.896 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr16_-_34262830 0.873 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr12_-_98577940 0.859 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr16_-_34263179 0.841 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr1_+_139454747 0.836 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr8_+_12915879 0.777 ENSMUST00000110876.2
ENSMUST00000110879.2
 Mcf2l

mcf.2 transforming sequence-like

chr18_+_33794915 0.776 ENSMUST00000179138.1
 2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr18_-_78123324 0.762 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr2_-_180824596 0.664 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr9_+_107296682 0.644 ENSMUST00000168260.1
 Cish
cytokine inducible SH2-containing protein
chr9_+_107296843 0.586 ENSMUST00000167072.1
 Cish
cytokine inducible SH2-containing protein
chr15_-_54919961 0.563 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr16_-_34262945 0.487 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chrX_+_153359613 0.427 ENSMUST00000039545.4
 Klf8
Kruppel-like factor 8
chr7_-_16221993 0.357 ENSMUST00000118795.1
ENSMUST00000119102.1
ENSMUST00000094816.2
ENSMUST00000163968.1
ENSMUST00000121123.1
 Dhx34




DEAH (Asp-Glu-Ala-His) box polypeptide 34




chr7_+_43579577 0.344 ENSMUST00000058104.7
 Zfp719
zinc finger protein 719
chr18_+_42275353 0.335 ENSMUST00000046972.7
ENSMUST00000091920.5
 Rbm27

RNA binding motif protein 27

chr11_+_95712673 0.329 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr2_+_175283298 0.319 ENSMUST00000098998.3
 Gm14440
predicted gene 14440
chr3_+_95588960 0.302 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr3_+_84925476 0.272 ENSMUST00000107675.1
 Fbxw7
F-box and WD-40 domain protein 7
chr10_-_86705485 0.246 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr1_+_82316452 0.244 ENSMUST00000027322.7
 Rhbdd1
rhomboid domain containing 1
chr8_+_25601591 0.215 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr18_+_33794882 0.215 ENSMUST00000146010.2
 2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr3_+_95588990 0.208 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr3_+_95588928 0.197 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like


chr11_+_58432559 0.182 ENSMUST00000108825.1
 Gm12253
predicted gene 12253
chr1_+_83159733 0.174 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
 Daw1


dynein assembly factor with WDR repeat domains 1


chr15_-_54920115 0.172 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_48623737 0.158 ENSMUST00000114936.1
 Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chrX_+_74429671 0.152 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
 Ikbkg


inhibitor of kappaB kinase gamma


chr9_-_95815389 0.149 ENSMUST00000119760.1
 Pls1
plastin 1 (I-isoform)
chr7_+_119900099 0.085 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr4_+_149485260 0.082 ENSMUST00000030842.7
 Lzic
leucine zipper and CTNNBIP1 domain containing
chr13_-_76018524 0.073 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
 Rfesd


Rieske (Fe-S) domain containing


chr1_+_191717834 0.051 ENSMUST00000110855.1
ENSMUST00000133076.1
 Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr4_+_3574872 0.050 ENSMUST00000052712.5
 Tgs1
trimethylguanosine synthase homolog (S. cerevisiae)
chr9_+_121938099 0.042 ENSMUST00000063103.4
 1700048O20Rik
RIKEN cDNA 1700048O20 gene
chr11_+_93098404 0.037 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
 Car10



carbonic anhydrase 10



chr2_-_155729359 0.033 ENSMUST00000040833.4
 Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr18_-_3281036 0.005 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
 Crem


cAMP responsive element modulator



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.7 6.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.7 3.4 GO:0046684 response to pyrethroid(GO:0046684)
0.6 1.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.6 2.6 GO:0035063 nuclear speck organization(GO:0035063)
0.4 2.8 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.3 2.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.8 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 3.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.8 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 2.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 2.0 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.0 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.7 GO:0005614 interstitial matrix(GO:0005614)
0.4 6.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 6.9 GO:0030673 axolemma(GO:0030673)
0.2 0.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 1.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.7 GO:0045545 syndecan binding(GO:0045545)
0.9 6.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 3.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 2.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 3.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.8 GO:0015265 urea channel activity(GO:0015265)
0.1 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)