Motif ID: Bhlhe40

Z-value: 0.533


Transcription factors associated with Bhlhe40:

Gene SymbolEntrez IDGene Name
Bhlhe40 ENSMUSG00000030103.5 Bhlhe40

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe40mm10_v2_chr6_+_108660616_108660682-0.531.5e-03Click!


Activity profile for motif Bhlhe40.

activity profile for motif Bhlhe40


Sorted Z-values histogram for motif Bhlhe40

Sorted Z-values for motif Bhlhe40



Network of associatons between targets according to the STRING database.



First level regulatory network of Bhlhe40

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_148039097 3.798 ENSMUST00000141283.1
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr4_+_148039035 3.113 ENSMUST00000097788.4
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr19_-_4201591 1.871 ENSMUST00000025740.6
 Rad9a
RAD9 homolog A
chrX_-_7188713 1.561 ENSMUST00000004428.7
 Clcn5
chloride channel 5
chr2_+_30286406 1.538 ENSMUST00000138666.1
ENSMUST00000113634.2
 Nup188

nucleoporin 188

chr2_+_30286383 1.404 ENSMUST00000064447.5
 Nup188
nucleoporin 188
chr4_-_137048695 1.258 ENSMUST00000049583.7
 Zbtb40
zinc finger and BTB domain containing 40
chr17_-_12769605 1.159 ENSMUST00000024599.7
 Igf2r
insulin-like growth factor 2 receptor
chr11_-_75348261 1.155 ENSMUST00000000767.5
ENSMUST00000092907.5
 Rpa1

replication protein A1

chr1_+_166254095 0.977 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr3_+_85574109 0.919 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
 Pet112


PET112 homolog (S. cerevisiae)


chrX_-_134600976 0.874 ENSMUST00000033621.6
 Gla
galactosidase, alpha
chr3_-_96727453 0.866 ENSMUST00000141377.1
ENSMUST00000125183.1
 Polr3c

polymerase (RNA) III (DNA directed) polypeptide C

chr12_-_79296266 0.854 ENSMUST00000021547.6
 Zfyve26
zinc finger, FYVE domain containing 26
chr3_-_90052463 0.842 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
 Ubap2l


ubiquitin associated protein 2-like


chr8_+_111033890 0.820 ENSMUST00000034441.7
 Aars
alanyl-tRNA synthetase
chr12_-_3426700 0.818 ENSMUST00000180149.1
 1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr3_-_96727566 0.778 ENSMUST00000029741.2
 Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chrX_+_136270253 0.768 ENSMUST00000178632.1
ENSMUST00000053540.4
 Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr3_-_96727436 0.762 ENSMUST00000154679.1
 Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr11_-_52000748 0.740 ENSMUST00000109086.1
 Ube2b
ubiquitin-conjugating enzyme E2B
chr19_-_7241216 0.716 ENSMUST00000025675.9
 Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr4_-_48473403 0.704 ENSMUST00000164866.1
ENSMUST00000030030.8
 Tex10

testis expressed gene 10

chr11_-_94653964 0.686 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr7_+_82648595 0.680 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
 Eftud1


elongation factor Tu GTP binding domain containing 1


chrX_+_153832225 0.676 ENSMUST00000148708.1
ENSMUST00000123264.1
ENSMUST00000049999.8
 Spin2c


spindlin family, member 2C


chr2_+_84839395 0.664 ENSMUST00000146816.1
ENSMUST00000028469.7
 Slc43a1

solute carrier family 43, member 1

chr7_+_128744870 0.651 ENSMUST00000042942.8
 Sec23ip
Sec23 interacting protein
chr3_-_95882031 0.577 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr3_-_95106907 0.570 ENSMUST00000107233.2
 Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr14_+_50924968 0.555 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
 Apex1


apurinic/apyrimidinic endonuclease 1


chr16_-_44139003 0.551 ENSMUST00000124102.1
 Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr1_-_152766323 0.535 ENSMUST00000111857.1
 Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chrX_+_136270302 0.533 ENSMUST00000113112.1
 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_92466081 0.529 ENSMUST00000060005.8
 Rcan1
regulator of calcineurin 1
chr8_+_85037151 0.513 ENSMUST00000166592.1
 Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr3_-_95106779 0.489 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
 Pip5k1a


phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha


chr14_+_26579535 0.482 ENSMUST00000037585.7
 Dennd6a
DENN/MADD domain containing 6A
chr7_-_35802968 0.481 ENSMUST00000061586.4
 Zfp507
zinc finger protein 507
chrX_+_134601179 0.460 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
 Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr8_+_85036906 0.453 ENSMUST00000093360.4
 Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr4_-_119422355 0.445 ENSMUST00000106316.1
ENSMUST00000030385.6
 Ppcs

phosphopantothenoylcysteine synthetase

chr16_-_5049882 0.444 ENSMUST00000023189.7
ENSMUST00000115844.1
 Glyr1

glyoxylate reductase 1 homolog (Arabidopsis)

chr16_+_5050012 0.437 ENSMUST00000052449.5
 Ubn1
ubinuclein 1
chr11_+_75348433 0.435 ENSMUST00000044530.2
 Smyd4
SET and MYND domain containing 4
chr5_+_65199691 0.418 ENSMUST00000041892.8
 Wdr19
WD repeat domain 19
chr7_-_90475971 0.415 ENSMUST00000032843.7
 Tmem126b
transmembrane protein 126B
chr5_-_123572976 0.413 ENSMUST00000031388.8
 Vps33a
vacuolar protein sorting 33A (yeast)
chr11_+_3649494 0.409 ENSMUST00000093389.2
 Morc2a
microrchidia 2A
chr10_+_79854658 0.395 ENSMUST00000171599.1
ENSMUST00000095457.4
 Ptbp1

polypyrimidine tract binding protein 1

chrX_+_136138996 0.392 ENSMUST00000116527.1
 Bex4
brain expressed gene 4
chr2_+_166805506 0.374 ENSMUST00000099078.3
 Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chrX_+_134601271 0.364 ENSMUST00000050331.6
ENSMUST00000059297.5
 Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr16_+_5233615 0.350 ENSMUST00000100196.2
ENSMUST00000049207.8
 Alg1

asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)

chr7_+_121707189 0.349 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr1_-_75219245 0.336 ENSMUST00000079464.6
 Tuba4a
tubulin, alpha 4A
chr10_+_79854618 0.323 ENSMUST00000165704.1
 Ptbp1
polypyrimidine tract binding protein 1
chr3_-_107333289 0.315 ENSMUST00000061772.9
 Rbm15
RNA binding motif protein 15
chr2_-_160619971 0.312 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr4_-_141790891 0.309 ENSMUST00000038014.4
ENSMUST00000153880.1
 Dnajc16

DnaJ (Hsp40) homolog, subfamily C, member 16

chr8_-_84846860 0.292 ENSMUST00000003912.6
 Calr
calreticulin
chr2_+_156840966 0.281 ENSMUST00000109564.1
 Tgif2
TGFB-induced factor homeobox 2
chr1_-_152766281 0.281 ENSMUST00000111859.1
ENSMUST00000148865.1
 Rgl1

ral guanine nucleotide dissociation stimulator,-like 1

chr5_+_104046980 0.280 ENSMUST00000134313.1
 Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr11_+_55204319 0.273 ENSMUST00000108872.2
ENSMUST00000147506.1
ENSMUST00000020499.7
 Slc36a1


solute carrier family 36 (proton/amino acid symporter), member 1


chr3_+_96727611 0.263 ENSMUST00000029740.9
 Rnf115
ring finger protein 115
chr5_+_104046526 0.261 ENSMUST00000150226.1
 Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr16_-_44139630 0.253 ENSMUST00000137557.1
ENSMUST00000147025.1
 Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr11_-_117780630 0.250 ENSMUST00000026659.3
ENSMUST00000127227.1
 Tmc6

transmembrane channel-like gene family 6

chr12_+_86947343 0.248 ENSMUST00000038369.4
 2310044G17Rik
RIKEN cDNA 2310044G17 gene
chr2_-_37703845 0.228 ENSMUST00000155237.1
 Strbp
spermatid perinuclear RNA binding protein
chr4_-_118490030 0.225 ENSMUST00000047421.5
 Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chrX_-_152327430 0.223 ENSMUST00000181635.1
ENSMUST00000141922.1
ENSMUST00000154085.1
ENSMUST00000148326.1
ENSMUST00000135115.1
ENSMUST00000149098.1
 2900056M20Rik





RIKEN cDNA 2900056M20 gene





chr6_+_72097561 0.218 ENSMUST00000069994.4
ENSMUST00000114112.1
 St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr17_-_33824346 0.216 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
 Rps28




ribosomal protein S28




chr11_+_95666957 0.214 ENSMUST00000125172.1
ENSMUST00000036374.5
 Phb

prohibitin

chr3_+_89202916 0.214 ENSMUST00000077367.4
ENSMUST00000167998.1
 Gba

glucosidase, beta, acid

chr10_-_62486772 0.207 ENSMUST00000105447.3
 Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr8_+_25601591 0.201 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr16_+_8830093 0.198 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr14_-_50930803 0.192 ENSMUST00000160538.1
ENSMUST00000162957.1
ENSMUST00000161166.1
ENSMUST00000160835.1
ENSMUST00000049312.7
 Tmem55b




transmembrane protein 55b




chr8_+_84689247 0.174 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
 Trmt1




tRNA methyltransferase 1




chr8_+_84689308 0.166 ENSMUST00000125370.3
ENSMUST00000175784.1
 Trmt1

tRNA methyltransferase 1

chr10_-_62486575 0.128 ENSMUST00000092473.3
 Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr5_+_104046869 0.112 ENSMUST00000031250.7
 Nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr11_+_97450136 0.110 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr16_-_44139196 0.088 ENSMUST00000063661.6
ENSMUST00000114666.2
 Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr15_+_80255184 0.081 ENSMUST00000109605.3
 Atf4
activating transcription factor 4
chr7_-_126583523 0.077 ENSMUST00000125508.1
ENSMUST00000147086.1
ENSMUST00000150587.1
 Cln3


ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)


chr1_+_155158703 0.077 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr9_+_108002501 0.048 ENSMUST00000035214.4
ENSMUST00000175874.1
 Ip6k1

inositol hexaphosphate kinase 1

chr14_-_50924626 0.027 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
 Osgep


O-sialoglycoprotein endopeptidase


chr3_-_95882193 0.022 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chrX_-_136068236 0.020 ENSMUST00000049130.7
 Bex2
brain expressed X-linked 2
chr9_-_44361625 0.017 ENSMUST00000034644.8
 Vps11
vacuolar protein sorting 11 (yeast)
chr6_+_116338013 0.012 ENSMUST00000079012.6
ENSMUST00000101032.3
 March8

membrane-associated ring finger (C3HC4) 8

chr3_-_95882232 0.010 ENSMUST00000161866.1
 Gm129
predicted gene 129
chr11_-_52000432 0.010 ENSMUST00000020657.6
 Ube2b
ubiquitin-conjugating enzyme E2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0070829 heterochromatin maintenance(GO:0070829)
0.3 0.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.7 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.7 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 0.7 GO:0046032 ADP catabolic process(GO:0046032)
0.2 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.1 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 1.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.5 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 2.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.2 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 2.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0033363 secretory granule organization(GO:0033363) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0002922 positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 2.9 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.1 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.7 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.9 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 1.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.2 GO:0000800 lateral element(GO:0000800)
0.1 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.5 1.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.6 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 2.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 2.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.3 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0047631 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.2 GO:0001851 complement component C3b binding(GO:0001851) proteinase activated receptor binding(GO:0031871)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 1.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)