Z-value: 0.862
Transcription factors associated with Brca1:
Activity-expression correlation:
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Showing 1 to 20 of 199 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihood Term Description
2.0
12.3
GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2
5.9
GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1
4.9
GO:0003333 amino acid transmembrane transport(GO:0003333)
0.5
4.1
GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2
2.6
GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0
2.5
GO:0042254 ribosome biogenesis(GO:0042254)
0.3
2.4
GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3
2.4
GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1
2.3
GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.3
2.2
GO:0016576 histone dephosphorylation(GO:0016576)
0.1
2.0
GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1
2.0
GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3
1.9
GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2
1.9
GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1
1.9
GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1
1.9
GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0
1.9
GO:2001222 regulation of neuron migration(GO:2001222)
0.4
1.8
GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0
1.8
GO:0007019 microtubule depolymerization(GO:0007019)
0.2
1.7
GO:0006610 ribosomal protein import into nucleus(GO:0006610)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihood Term Description
1.4
4.1
GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0
3.2
GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0
2.8
GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2
2.4
GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0
2.4
GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0
2.4
GO:0005643 nuclear pore(GO:0005643)
0.1
2.3
GO:0031512 motile primary cilium(GO:0031512)
0.4
2.2
GO:1990635 proximal dendrite(GO:1990635)
0.2
2.0
GO:0001739 sex chromatin(GO:0001739)
0.3
1.9
GO:0000125 PCAF complex(GO:0000125)
0.1
1.9
GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1
1.9
GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0
1.5
GO:0005911 cell-cell junction(GO:0005911)
0.1
1.4
GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1
1.4
GO:0005921 gap junction(GO:0005921)
0.1
1.2
GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1
1.2
GO:0045298 tubulin complex(GO:0045298)
0.0
1.2
GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0
1.2
GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0
1.2
GO:0017053 transcriptional repressor complex(GO:0017053)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
9.5
GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
2.0
5.9
GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1
4.9
GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0
4.9
GO:0003735 structural constituent of ribosome(GO:0003735)
0.6
4.1
GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2
4.1
GO:0008432 JUN kinase binding(GO:0008432)
0.2
3.3
GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1
3.3
GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1
2.7
GO:0005109 frizzled binding(GO:0005109)
0.0
2.7
GO:0003714 transcription corepressor activity(GO:0003714)
0.1
2.5
GO:0001222 transcription corepressor binding(GO:0001222)
0.4
2.4
GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1
2.4
GO:0070064 proline-rich region binding(GO:0070064)
0.1
2.2
GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1
1.9
GO:0001054 RNA polymerase I activity(GO:0001054)
0.1
1.9
GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1
1.8
GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.6
1.7
GO:0008502 melatonin receptor activity(GO:0008502)
0.0
1.7
GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0
1.6
GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
