Motif ID: Chd1_Pml

Z-value: 5.094

Transcription factors associated with Chd1_Pml:

Gene SymbolEntrez IDGene Name
Chd1 ENSMUSG00000023852.7 Chd1
Pml ENSMUSG00000036986.10 Pml

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Chd1mm10_v2_chr17_+_15704963_157049940.308.6e-02Click!
Pmlmm10_v2_chr9_-_58249660_58249672-0.212.4e-01Click!


Activity profile for motif Chd1_Pml.

activity profile for motif Chd1_Pml


Sorted Z-values histogram for motif Chd1_Pml

Sorted Z-values for motif Chd1_Pml



Network of associatons between targets according to the STRING database.



First level regulatory network of Chd1_Pml

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800024 105.225 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr8_-_84800344 81.352 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chrX_+_170009659 69.889 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr15_-_66286224 61.325 ENSMUST00000070256.7
 Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr4_-_120287349 56.359 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr6_+_99692679 48.335 ENSMUST00000101122.1
 Gpr27
G protein-coupled receptor 27
chr2_+_155775333 43.097 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr6_-_32588192 40.777 ENSMUST00000115096.2
 Plxna4
plexin A4
chr12_-_4477138 39.699 ENSMUST00000085814.3
 Ncoa1
nuclear receptor coactivator 1
chrX_+_170009892 37.584 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr6_-_114042020 37.383 ENSMUST00000101045.3
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr4_+_97777780 37.194 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr16_-_67620880 35.290 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr11_-_6065737 32.632 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr15_-_12321899 32.611 ENSMUST00000180521.1
 1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr4_+_124657646 30.279 ENSMUST00000053491.7
 Pou3f1
POU domain, class 3, transcription factor 1
chr4_-_129121699 28.768 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr16_-_67620805 28.519 ENSMUST00000120594.1
 Cadm2
cell adhesion molecule 2
chr6_+_54816906 28.403 ENSMUST00000079869.6
 Znrf2
zinc and ring finger 2
chr1_-_119422239 28.017 ENSMUST00000038765.5
 Inhbb
inhibin beta-B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 895 entries
Log-likelihood per target Total log-likelihoodTermDescription
16.2 227.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
3.9 113.4 GO:0060074 synapse maturation(GO:0060074)
6.4 102.1 GO:0060081 membrane hyperpolarization(GO:0060081)
6.3 100.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.4 95.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
4.0 91.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8 89.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.6 82.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
3.9 67.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
22.1 66.3 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
9.1 63.9 GO:0045925 positive regulation of female receptivity(GO:0045925)
21.2 63.5 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
2.0 54.2 GO:2001222 regulation of neuron migration(GO:2001222)
4.1 53.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
17.5 52.5 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
5.8 52.4 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
1.0 51.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.4 50.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
1.3 50.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
5.4 48.3 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 276 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 355.8 GO:0016021 integral component of membrane(GO:0016021)
1.3 241.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 180.3 GO:0005768 endosome(GO:0005768)
3.9 139.3 GO:0032809 neuronal cell body membrane(GO:0032809)
1.1 137.8 GO:0031225 anchored component of membrane(GO:0031225)
4.4 130.6 GO:0043194 axon initial segment(GO:0043194)
3.4 123.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.0 118.6 GO:0070382 exocytic vesicle(GO:0070382)
1.4 116.4 GO:0043195 terminal bouton(GO:0043195)
1.8 111.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
2.7 98.9 GO:0048786 presynaptic active zone(GO:0048786)
1.5 91.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.9 91.5 GO:0055037 recycling endosome(GO:0055037)
2.9 77.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
7.3 73.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
7.3 73.0 GO:0044327 dendritic spine head(GO:0044327)
2.3 72.1 GO:0051233 spindle midzone(GO:0051233)
0.5 71.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.9 66.3 GO:0043204 perikaryon(GO:0043204)
4.1 66.1 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 490 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 258.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.8 156.1 GO:0003714 transcription corepressor activity(GO:0003714)
5.4 150.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.1 98.7 GO:0045296 cadherin binding(GO:0045296)
0.5 96.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.4 85.6 GO:0005096 GTPase activator activity(GO:0005096)
1.1 76.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.6 72.6 GO:0045499 chemorepellent activity(GO:0045499)
3.0 71.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
2.8 68.0 GO:0017075 syntaxin-1 binding(GO:0017075)
3.6 65.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
1.7 63.6 GO:0001540 beta-amyloid binding(GO:0001540)
4.2 58.9 GO:0017154 semaphorin receptor activity(GO:0017154)
2.4 58.3 GO:0043274 phospholipase binding(GO:0043274)
4.1 57.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 57.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
4.3 55.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.6 55.4 GO:0016247 channel regulator activity(GO:0016247)
3.1 55.1 GO:0004890 GABA-A receptor activity(GO:0004890)
9.0 54.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)