Motif ID: Creb1

Z-value: 1.855


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.697.5e-06Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_56535047 8.871 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr7_-_137314394 7.452 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr7_-_38107490 6.034 ENSMUST00000108023.3
 Ccne1
cyclin E1
chr11_+_43528759 5.575 ENSMUST00000050574.6
 Ccnjl
cyclin J-like
chr15_-_76710486 5.435 ENSMUST00000036852.7
 Recql4
RecQ protein-like 4
chr14_-_31251194 5.424 ENSMUST00000022459.3
 Phf7
PHD finger protein 7
chr17_+_46646225 4.567 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
 Mrpl2


mitochondrial ribosomal protein L2


chr11_-_106160101 4.561 ENSMUST00000045923.3
 Limd2
LIM domain containing 2
chr14_+_31251454 4.358 ENSMUST00000022458.4
 Bap1
Brca1 associated protein 1
chr7_+_3629985 4.327 ENSMUST00000008517.6
ENSMUST00000179769.1
 Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr19_+_6084983 4.141 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr4_+_107879745 4.100 ENSMUST00000030348.5
 Magoh
mago-nashi homolog, proliferation-associated (Drosophila)
chr5_+_112343068 4.080 ENSMUST00000112359.2
ENSMUST00000035279.3
 Hps4

Hermansky-Pudlak syndrome 4 homolog (human)

chr7_-_30664986 3.991 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr19_+_5041337 3.907 ENSMUST00000116567.2
 Brms1
breast cancer metastasis-suppressor 1
chr12_+_52097737 3.789 ENSMUST00000040090.9
 Nubpl
nucleotide binding protein-like
chr5_-_24577467 3.720 ENSMUST00000030795.8
 Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr8_-_123949201 3.720 ENSMUST00000044795.7
 Nup133
nucleoporin 133
chr5_+_124579134 3.694 ENSMUST00000031333.3
 Gtf2h3
general transcription factor IIH, polypeptide 3
chr5_-_110653348 3.622 ENSMUST00000042147.5
 Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.2 GO:0006364 rRNA processing(GO:0006364)
0.5 9.2 GO:0006999 nuclear pore organization(GO:0006999)
3.0 8.9 GO:0021759 globus pallidus development(GO:0021759)
0.7 8.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 8.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
2.0 8.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2 8.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.4 7.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
1.6 6.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.5 6.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 6.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 6.2 GO:0098792 xenophagy(GO:0098792)
1.1 5.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
1.7 5.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.3 5.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 5.0 GO:0032543 mitochondrial translation(GO:0032543)
0.2 4.8 GO:0030488 tRNA methylation(GO:0030488)
1.1 4.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 4.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
1.4 4.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 8.8 GO:0005730 nucleolus(GO:0005730)
0.1 8.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 8.0 GO:0043198 dendritic shaft(GO:0043198)
0.2 7.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.5 7.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
2.1 6.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3 6.3 GO:0000346 transcription export complex(GO:0000346)
0.3 6.2 GO:0001650 fibrillar center(GO:0001650)
0.1 5.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 5.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 5.7 GO:0070822 Sin3-type complex(GO:0070822)
0.1 5.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.8 5.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 5.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 4.8 GO:0005871 kinesin complex(GO:0005871)
0.7 4.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 4.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 4.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 132 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.3 GO:0044822 poly(A) RNA binding(GO:0044822)
0.2 16.0 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 12.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 11.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 9.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.8 9.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.3 8.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
1.1 6.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.9 6.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 6.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
1.1 5.4 GO:0000405 bubble DNA binding(GO:0000405)
0.1 5.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 5.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 4.6 GO:0031491 nucleosome binding(GO:0031491)
0.3 4.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 4.5 GO:0017160 Ral GTPase binding(GO:0017160)
1.5 4.4 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 4.4 GO:0051082 unfolded protein binding(GO:0051082)
0.9 4.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 4.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)