Motif ID: Crem_Jdp2

Z-value: 0.579

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Jdp2mm10_v2_chr12_+_85599047_855991050.681.4e-05Click!
Cremmm10_v2_chr18_-_3337539_33376000.411.9e-02Click!


Activity profile for motif Crem_Jdp2.

activity profile for motif Crem_Jdp2


Sorted Z-values histogram for motif Crem_Jdp2

Sorted Z-values for motif Crem_Jdp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_45885479 4.176 ENSMUST00000034053.5
 Pdlim3
PDZ and LIM domain 3
chr7_+_112679327 2.830 ENSMUST00000106638.2
 Tead1
TEA domain family member 1
chrX_+_66653003 2.768 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr15_-_12321899 2.767 ENSMUST00000180521.1
 1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr7_+_112679314 2.765 ENSMUST00000084705.5
ENSMUST00000059768.10
 Tead1

TEA domain family member 1

chr5_-_124032214 2.764 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr6_+_112273758 2.047 ENSMUST00000032376.5
 Lmcd1
LIM and cysteine-rich domains 1
chr9_-_52679429 1.992 ENSMUST00000098768.2
 AI593442
expressed sequence AI593442
chr10_-_17947997 1.886 ENSMUST00000037879.6
 Heca
headcase homolog (Drosophila)
chr7_+_79500018 1.799 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr13_+_19623163 1.665 ENSMUST00000002883.5
 Sfrp4
secreted frizzled-related protein 4
chr1_+_135729147 1.629 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr7_+_79500081 1.604 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr11_-_88718223 1.583 ENSMUST00000107909.1
 Msi2
musashi RNA-binding protein 2
chr1_+_95313607 1.579 ENSMUST00000059975.6
 Fam174a
family with sequence similarity 174, member A
chr4_+_11704439 1.576 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr3_-_146108047 1.557 ENSMUST00000160285.1
 Wdr63
WD repeat domain 63
chr11_-_90390895 1.554 ENSMUST00000004051.7
 Hlf
hepatic leukemia factor
chr11_+_94044331 1.479 ENSMUST00000024979.8
 Spag9
sperm associated antigen 9
chr9_-_20976762 1.477 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 147 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.7 5.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.9 2.8 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.9 2.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.4 2.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 2.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 2.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 2.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 1.7 GO:0048388 endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401)
0.6 1.7 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 1.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.6 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.6 GO:0070527 platelet aggregation(GO:0070527)
0.5 1.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 1.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.4 1.3 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.3 1.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0030018 Z disc(GO:0030018)
0.4 3.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 2.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.7 GO:0042581 specific granule(GO:0042581)
0.0 1.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.5 GO:0051233 spindle midzone(GO:0051233)
0.0 1.5 GO:0005844 polysome(GO:0005844)
0.2 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.3 0.8 GO:0097447 dendritic tree(GO:0097447)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 4.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 2.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.4 GO:0019003 GDP binding(GO:0019003)
0.5 2.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 1.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 1.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.5 GO:0030332 cyclin binding(GO:0030332)
0.4 1.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.4 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 1.3 GO:0048487 beta-tubulin binding(GO:0048487)