Motif ID: Cux1

Z-value: 0.620


Transcription factors associated with Cux1:

Gene SymbolEntrez IDGene Name
Cux1 ENSMUSG00000029705.11 Cux1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cux1mm10_v2_chr5_-_136567242_1365672870.402.2e-02Click!


Activity profile for motif Cux1.

activity profile for motif Cux1


Sorted Z-values histogram for motif Cux1

Sorted Z-values for motif Cux1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cux1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_96210107 2.410 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr5_+_117841839 2.392 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr5_-_145201829 2.093 ENSMUST00000162220.1
ENSMUST00000031632.8
 Zkscan14

zinc finger with KRAB and SCAN domains 14

chr7_-_19166119 1.928 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr9_-_58204310 1.601 ENSMUST00000114144.2
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_88875035 1.586 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr10_+_79879614 1.584 ENSMUST00000006679.8
 Prtn3
proteinase 3
chr5_-_122050102 1.557 ENSMUST00000154139.1
 Cux2
cut-like homeobox 2
chr5_-_84417359 1.492 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr2_+_71528657 1.402 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr12_+_55598917 1.381 ENSMUST00000051857.3
 Insm2
insulinoma-associated 2
chr11_+_58954675 1.345 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr1_-_84935089 1.321 ENSMUST00000027422.5
 Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr13_-_30974023 1.281 ENSMUST00000021785.6
 Exoc2
exocyst complex component 2
chr2_+_158610731 1.277 ENSMUST00000045738.4
 Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr12_+_105453831 1.275 ENSMUST00000178224.1
 D430019H16Rik
RIKEN cDNA D430019H16 gene
chr4_+_119814495 1.263 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr13_-_110280103 1.231 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr1_+_66386968 1.228 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr1_-_83408190 1.223 ENSMUST00000160953.1
 Sphkap
SPHK1 interactor, AKAP domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 139 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 2.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.8 2.4 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.6 2.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.6 2.4 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 2.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 1.6 GO:0071569 protein ufmylation(GO:0071569)
0.1 1.6 GO:0007614 short-term memory(GO:0007614)
0.2 1.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.2 1.3 GO:0001927 exocyst assembly(GO:0001927)
0.1 1.3 GO:0015816 glycine transport(GO:0015816)
0.1 1.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.3 1.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0070382 exocytic vesicle(GO:0070382)
0.2 2.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.3 1.3 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.2 GO:0030018 Z disc(GO:0030018)
0.1 1.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.8 2.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 2.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 2.4 GO:0005516 calmodulin binding(GO:0005516)
0.3 2.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.5 GO:0031489 myosin V binding(GO:0031489)
0.0 1.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.4 1.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.2 1.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)