Motif ID: Cxxc1

Z-value: 0.396


Transcription factors associated with Cxxc1:

Gene SymbolEntrez IDGene Name
Cxxc1 ENSMUSG00000024560.6 Cxxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cxxc1mm10_v2_chr18_+_74216118_74216145-0.521.8e-03Click!


Activity profile for motif Cxxc1.

activity profile for motif Cxxc1


Sorted Z-values histogram for motif Cxxc1

Sorted Z-values for motif Cxxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cxxc1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_89302545 1.298 ENSMUST00000061728.3
 Nog
noggin
chr11_-_69921057 0.977 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr12_+_110279228 0.939 ENSMUST00000097228.4
 Dio3
deiodinase, iodothyronine type III
chr7_-_49636847 0.920 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr11_-_69920892 0.719 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
 Eif5a


eukaryotic translation initiation factor 5A


chr17_-_14203695 0.669 ENSMUST00000053218.5
 Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr3_-_8964037 0.645 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr8_+_92357787 0.574 ENSMUST00000034184.10
 Irx5
Iroquois related homeobox 5 (Drosophila)
chr19_-_4439388 0.534 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr8_-_111393810 0.499 ENSMUST00000038475.8
 Fa2h
fatty acid 2-hydroxylase
chr8_+_70594466 0.495 ENSMUST00000019283.9
 Isyna1
myo-inositol 1-phosphate synthase A1
chr11_-_69920581 0.459 ENSMUST00000108610.1
 Eif5a
eukaryotic translation initiation factor 5A
chr11_+_32205483 0.438 ENSMUST00000121182.1
 Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr3_-_101307079 0.434 ENSMUST00000097146.2
 Gm10355
predicted gene 10355
chr11_-_68386974 0.427 ENSMUST00000135141.1
 Ntn1
netrin 1
chr5_-_65391408 0.394 ENSMUST00000057885.6
 Rpl9
ribosomal protein L9
chr11_+_32205411 0.378 ENSMUST00000039601.3
ENSMUST00000149043.1
 Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr10_+_128058974 0.377 ENSMUST00000084771.2
 Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_-_125389177 0.367 ENSMUST00000108707.2
 Ubc
ubiquitin C
chr10_+_128058947 0.365 ENSMUST00000052798.7
 Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_-_65391380 0.363 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
 Rpl9


ribosomal protein L9


chr1_-_124045523 0.334 ENSMUST00000112606.1
 Dpp10
dipeptidylpeptidase 10
chr5_-_4758216 0.309 ENSMUST00000054294.4
 Fzd1
frizzled homolog 1 (Drosophila)
chr11_+_88068242 0.306 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr2_+_112239468 0.288 ENSMUST00000028554.3
 Lpcat4
lysophosphatidylcholine acyltransferase 4
chr11_+_80383279 0.286 ENSMUST00000165565.1
ENSMUST00000017567.7
 Zfp207

zinc finger protein 207

chr1_-_124045247 0.268 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr1_-_180813534 0.251 ENSMUST00000159789.1
ENSMUST00000081026.4
 H3f3a

H3 histone, family 3A

chr10_+_50895651 0.250 ENSMUST00000020071.3
 Sim1
single-minded homolog 1 (Drosophila)
chr19_+_38931008 0.239 ENSMUST00000145051.1
 Hells
helicase, lymphoid specific
chr10_-_79766872 0.221 ENSMUST00000047203.8
 Rnf126
ring finger protein 126
chr10_+_80249441 0.196 ENSMUST00000020361.6
 Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr8_-_122443404 0.153 ENSMUST00000006692.4
 Mvd
mevalonate (diphospho) decarboxylase
chr18_-_43477764 0.144 ENSMUST00000057110.9
 Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr5_-_125389915 0.142 ENSMUST00000136312.1
 Ubc
ubiquitin C
chr10_+_126978690 0.139 ENSMUST00000105256.2
 Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr12_-_54656496 0.121 ENSMUST00000056228.6
 Sptssa
serine palmitoyltransferase, small subunit A
chr5_+_65391497 0.117 ENSMUST00000031101.3
ENSMUST00000122026.1
 Lias

lipoic acid synthetase

chr5_+_143403819 0.116 ENSMUST00000110731.2
 Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr5_+_125389284 0.086 ENSMUST00000100700.2
 Gm10382
predicted gene 10382
chr17_+_86963279 0.072 ENSMUST00000139344.1
 Rhoq
ras homolog gene family, member Q
chrX_+_48623737 0.054 ENSMUST00000114936.1
 Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr19_-_36919606 0.054 ENSMUST00000057337.7
 Fgfbp3
fibroblast growth factor binding protein 3
chr5_+_30588078 0.052 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr15_+_74516196 0.045 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr7_-_4501636 0.044 ENSMUST00000013886.8
 Ppp1r12c
protein phosphatase 1, regulatory (inhibitor) subunit 12C
chr10_-_7681118 0.028 ENSMUST00000159977.1
ENSMUST00000162682.1
 Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr11_+_60537978 0.025 ENSMUST00000044250.3
 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr7_+_128744870 0.022 ENSMUST00000042942.8
 Sec23ip
Sec23 interacting protein
chr11_-_17953861 0.020 ENSMUST00000076661.6
 Etaa1
Ewing's tumor-associated antigen 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 0.7 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.2 0.9 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.2 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.6 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:1990047 spindle matrix(GO:1990047)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 2.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)