Motif ID: Dlx1
Z-value: 1.198
Transcription factors associated with Dlx1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Dlx1 | ENSMUSG00000041911.3 | Dlx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Dlx1 | mm10_v2_chr2_+_71529085_71529110 | 0.40 | 2.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 14.0 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 1.5 | 5.8 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
| 1.5 | 4.4 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.2 | 4.7 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 1.1 | 3.4 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 1.1 | 3.3 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
| 1.0 | 3.0 | GO:1904395 | retinal rod cell differentiation(GO:0060221) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.9 | 2.7 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.9 | 2.6 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.9 | 5.1 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.8 | 2.4 | GO:0002554 | serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366) |
| 0.7 | 2.2 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.7 | 3.5 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.6 | 8.2 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.5 | 3.8 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.5 | 3.8 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.5 | 1.6 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 0.5 | 2.6 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.5 | 1.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.4 | 1.8 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.4 | 2.0 | GO:0042167 | heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.4 | 1.2 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.4 | 1.5 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.4 | 1.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.4 | 1.1 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.3 | 0.9 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.3 | 0.9 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.3 | 0.9 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.3 | 1.7 | GO:0036233 | glycine import(GO:0036233) |
| 0.3 | 0.9 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 1.7 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.3 | 1.4 | GO:0015819 | lysine transport(GO:0015819) |
| 0.3 | 0.8 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) cerebellum vasculature development(GO:0061300) |
| 0.3 | 1.9 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.3 | 1.1 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.3 | 3.2 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.3 | 2.1 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.3 | 1.8 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.3 | 1.8 | GO:0032782 | urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918) |
| 0.3 | 0.8 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.2 | 2.0 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 1.0 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.2 | 0.7 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.2 | 1.9 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.2 | 2.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.2 | 6.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.2 | 1.6 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.3 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
| 0.2 | 1.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.2 | 1.2 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.2 | 5.9 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.2 | 2.2 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.2 | 0.6 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.2 | 0.5 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.2 | 3.3 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.2 | 1.1 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.7 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 5.1 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.1 | 0.5 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 1.2 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.1 | 1.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 0.4 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.1 | 0.6 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.1 | 1.0 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 2.6 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 1.1 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.1 | 1.2 | GO:0051923 | sulfation(GO:0051923) |
| 0.1 | 0.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 8.3 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.1 | 1.4 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 0.7 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 0.7 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 0.3 | GO:1904742 | protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742) |
| 0.1 | 2.7 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.1 | 2.3 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 0.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.8 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 0.7 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 0.2 | GO:0009193 | pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048) |
| 0.1 | 0.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 1.3 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.1 | 6.2 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 0.5 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
| 0.1 | 0.5 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.2 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
| 0.1 | 0.4 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.1 | 2.1 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.1 | 2.5 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.1 | 0.3 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
| 0.0 | 0.1 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.0 | 0.7 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.6 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
| 0.0 | 0.7 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.0 | 0.2 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 1.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.3 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 1.3 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.4 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.0 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.4 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.4 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 2.8 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.1 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
| 0.0 | 0.2 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.0 | 0.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 1.4 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.8 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 0.0 | 0.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.7 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.7 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.0 | 1.9 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.0 | 0.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.0 | 0.9 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 0.2 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.1 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.0 | 0.3 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 1.3 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 2.1 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.2 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.0 | 1.1 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 1.1 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 1.2 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
| 0.0 | 0.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.0 | 0.5 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 0.9 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.1 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.0 | 1.8 | GO:0019882 | antigen processing and presentation(GO:0019882) |
| 0.0 | 0.1 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.0 | 0.5 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.0 | 0.2 | GO:0045019 | negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406) |
| 0.0 | 0.4 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.3 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 1.9 | GO:0042493 | response to drug(GO:0042493) |
| 0.0 | 0.3 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.0 | 0.5 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
| 0.0 | 0.2 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.7 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.0 | 0.3 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.0 | 0.3 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.0 | 0.8 | GO:0030509 | BMP signaling pathway(GO:0030509) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 14.0 | GO:0043205 | fibril(GO:0043205) |
| 0.8 | 3.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.6 | 2.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.5 | 8.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.4 | 2.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 8.2 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.3 | 6.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.2 | 0.5 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.2 | 0.9 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 1.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 0.9 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.2 | 1.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.1 | 0.8 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.1 | 0.5 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
| 0.1 | 1.1 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.1 | 0.8 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.5 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.7 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 2.8 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 1.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 2.5 | GO:0005856 | cytoskeleton(GO:0005856) |
| 0.1 | 0.8 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.9 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 2.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.2 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 5.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 0.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 1.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 7.3 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 0.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.1 | 0.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 2.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.8 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.5 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.1 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.0 | 0.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 2.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 2.6 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.2 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 2.4 | GO:0030054 | cell junction(GO:0030054) |
| 0.0 | 0.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 4.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 3.4 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 1.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 3.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 1.0 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 1.4 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 3.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 7.0 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 2.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 1.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.4 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.0 | 0.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 2.5 | GO:0005911 | cell-cell junction(GO:0005911) |
| 0.0 | 0.6 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 16.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 1.7 | 5.1 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 1.7 | 5.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 1.0 | 3.0 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.0 | 2.9 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.9 | 3.5 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.5 | 2.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.5 | 2.0 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.5 | 3.8 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.4 | 3.4 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.4 | 1.3 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.4 | 1.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.4 | 1.6 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.4 | 1.6 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.4 | 2.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 6.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.3 | 1.8 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.3 | 2.4 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.3 | 1.7 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.3 | 2.0 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.3 | 8.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.3 | 0.8 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
| 0.2 | 1.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.2 | 0.9 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.2 | 10.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.2 | 5.0 | GO:0043747 | protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790) |
| 0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 4.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 1.7 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.2 | 8.2 | GO:0043015 | cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015) |
| 0.2 | 1.4 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
| 0.2 | 3.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.2 | 0.8 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
| 0.2 | 0.9 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.2 | 2.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.2 | 2.6 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.2 | 1.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.2 | 3.0 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.2 | 3.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.2 | 0.5 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.2 | 0.9 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.2 | 1.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 0.4 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.1 | 4.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 0.5 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.1 | 1.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 1.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.9 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.1 | 0.4 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 1.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 1.1 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 2.1 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 0.7 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.1 | 1.8 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.1 | 0.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 2.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.8 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 1.5 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.1 | 0.3 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.1 | 1.4 | GO:0017161 | JUN kinase phosphatase activity(GO:0008579) phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.1 | 0.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.4 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.1 | 1.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 1.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 1.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.7 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.3 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 1.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.1 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 0.0 | 1.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 2.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 5.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.1 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 0.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.2 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.0 | 8.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 1.6 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.2 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.0 | 0.3 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.0 | 0.9 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.1 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
| 0.0 | 0.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 8.9 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
| 0.0 | 1.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.4 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.2 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 0.0 | 2.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.7 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.0 | 2.0 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 3.6 | GO:0008168 | methyltransferase activity(GO:0008168) |
| 0.0 | 1.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.9 | GO:0046921 | alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.0 | 0.6 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 0.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.3 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.0 | 0.1 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.0 | 0.0 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 0.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
