Motif ID: E2f4

Z-value: 1.944


Transcription factors associated with E2f4:

Gene SymbolEntrez IDGene Name
E2f4 ENSMUSG00000014859.8 E2f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f4mm10_v2_chr8_+_105297663_1052977420.705.6e-06Click!


Activity profile for motif E2f4.

activity profile for motif E2f4


Sorted Z-values histogram for motif E2f4

Sorted Z-values for motif E2f4



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_132345686 10.950 ENSMUST00000030726.6
Rcc1
regulator of chromosome condensation 1
chr4_-_132345715 10.511 ENSMUST00000084250.4
Rcc1
regulator of chromosome condensation 1
chr4_+_134510999 9.121 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr2_-_172940299 7.886 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr19_+_6084983 7.833 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr12_+_117843873 7.605 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr6_+_124830217 6.567 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr14_-_47418407 6.241 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr17_-_24251382 6.236 ENSMUST00000115390.3
Ccnf
cyclin F
chr1_-_169531343 6.111 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_157412352 6.020 ENSMUST00000061537.5
2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr18_-_34751502 5.908 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr7_-_38107490 5.728 ENSMUST00000108023.3
Ccne1
cyclin E1
chr2_+_163054682 5.652 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr9_+_92250039 5.639 ENSMUST00000093801.3
Plscr1
phospholipid scramblase 1
chr1_-_169531447 5.625 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_+_44134562 5.438 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr4_-_116123618 5.335 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chr16_-_90727329 5.198 ENSMUST00000099554.4
Mis18a
MIS18 kinetochore protein homolog A (S. pombe)
chr6_-_56704673 5.140 ENSMUST00000170382.2
Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_133967235 5.140 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_-_72212249 5.038 ENSMUST00000048860.7
Mreg
melanoregulin
chr13_-_73937761 4.899 ENSMUST00000022053.8
Trip13
thyroid hormone receptor interactor 13
chr9_+_72438534 4.890 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr18_+_34751803 4.689 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr4_-_133967296 4.644 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_-_57377476 4.636 ENSMUST00000181949.1
4930558J18Rik
RIKEN cDNA 4930558J18 gene
chr10_+_88147061 4.596 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr9_+_72438519 4.570 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr17_-_84187939 4.422 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr17_-_25727364 4.414 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr10_+_88146992 4.354 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr11_+_98907801 4.259 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chrX_+_105079761 4.237 ENSMUST00000119477.1
Pbdc1
polysaccharide biosynthesis domain containing 1
chr17_+_50698525 4.178 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr17_+_87975044 4.069 ENSMUST00000005503.3
Msh6
mutS homolog 6 (E. coli)
chrX_+_164980592 4.066 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb


Fanconi anemia, complementation group B


chr11_-_106999369 3.935 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr11_-_106999482 3.829 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr11_-_101551837 3.821 ENSMUST00000017290.4
Brca1
breast cancer 1
chr2_-_26503814 3.779 ENSMUST00000028288.4
Notch1
notch 1
chrX_+_105079735 3.701 ENSMUST00000033577.4
Pbdc1
polysaccharide biosynthesis domain containing 1
chr5_-_25705791 3.605 ENSMUST00000030773.7
Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr14_-_65953728 3.525 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr9_+_107950952 3.503 ENSMUST00000049348.3
Traip
TRAF-interacting protein
chr10_-_88146867 3.432 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr4_-_58553553 3.314 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr5_+_9100681 3.292 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr7_-_127260677 3.146 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr5_+_33721724 3.132 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
Fgfr3



fibroblast growth factor receptor 3



chr1_-_33669745 3.028 ENSMUST00000027312.9
Prim2
DNA primase, p58 subunit
chr2_+_129592914 3.010 ENSMUST00000103203.1
Sirpa
signal-regulatory protein alpha
chrX_-_8074720 2.917 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr12_-_4233958 2.902 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr17_+_29490812 2.891 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr8_+_18595526 2.879 ENSMUST00000146819.1
Mcph1
microcephaly, primary autosomal recessive 1
chr12_-_87147883 2.851 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr7_+_97371604 2.826 ENSMUST00000098300.4
Alg8
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr4_-_133967893 2.794 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr3_-_107969162 2.760 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr2_+_129593195 2.724 ENSMUST00000099113.3
ENSMUST00000103202.3
Sirpa

signal-regulatory protein alpha

chr2_+_71786923 2.645 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr8_+_18595131 2.642 ENSMUST00000039412.8
Mcph1
microcephaly, primary autosomal recessive 1
chr18_-_39490649 2.591 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr15_-_76639840 2.578 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr4_-_58553311 2.574 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chr2_+_153649617 2.454 ENSMUST00000109771.1
Dnmt3b
DNA methyltransferase 3B
chr5_-_33652296 2.453 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr2_+_103970221 2.409 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr9_+_118926453 2.396 ENSMUST00000073109.5
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr15_+_57912199 2.395 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chrX_+_36112110 2.352 ENSMUST00000033418.7
Il13ra1
interleukin 13 receptor, alpha 1
chr2_+_129593528 2.344 ENSMUST00000049262.7
ENSMUST00000163034.1
ENSMUST00000160276.1
Sirpa


signal-regulatory protein alpha


chr4_+_11558914 2.282 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr9_+_119937606 2.272 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chr2_+_163204483 2.259 ENSMUST00000128999.1
Tox2
TOX high mobility group box family member 2
chr14_-_87141114 2.255 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chr2_+_30286406 2.226 ENSMUST00000138666.1
ENSMUST00000113634.2
Nup188

nucleoporin 188

chr4_-_43562397 2.220 ENSMUST00000030187.7
Tln1
talin 1
chr7_+_58658181 2.208 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr9_-_103365769 2.198 ENSMUST00000035484.4
ENSMUST00000072249.6
Cdv3

carnitine deficiency-associated gene expressed in ventricle 3

chr6_+_113531675 2.169 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr16_-_59632520 2.138 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr5_-_33652339 2.094 ENSMUST00000075670.6
Slbp
stem-loop binding protein
chr17_-_87025353 2.024 ENSMUST00000024957.6
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
chr15_-_37791993 1.955 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr1_+_9798123 1.930 ENSMUST00000168907.1
ENSMUST00000166384.1
Sgk3

serum/glucocorticoid regulated kinase 3

chr1_-_189688074 1.888 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr18_-_60848911 1.864 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr8_-_53638945 1.862 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr18_+_56707725 1.856 ENSMUST00000025486.8
Lmnb1
lamin B1
chr1_+_134415414 1.806 ENSMUST00000112237.1
Adipor1
adiponectin receptor 1
chr4_-_133967953 1.756 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr15_-_98831498 1.705 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr3_+_88553716 1.702 ENSMUST00000008748.6
Ubqln4
ubiquilin 4
chr4_-_58553184 1.674 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr7_-_92874196 1.659 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr5_+_21372642 1.644 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr17_+_34982154 1.547 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_34982099 1.520 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_-_78583782 1.516 ENSMUST00000177904.1
Prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr14_-_54517353 1.515 ENSMUST00000023873.5
Prmt5
protein arginine N-methyltransferase 5
chr15_+_102406143 1.510 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr19_+_5366764 1.488 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr5_-_138172383 1.462 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_-_78583882 1.430 ENSMUST00000114025.1
ENSMUST00000134602.1
ENSMUST00000114024.2
Prrg1


proline rich Gla (G-carboxyglutamic acid) 1


chr10_-_19907645 1.418 ENSMUST00000166511.1
ENSMUST00000020182.8
Pex7

peroxisomal biogenesis factor 7

chr14_-_87141206 1.412 ENSMUST00000022599.7
Diap3
diaphanous homolog 3 (Drosophila)
chr1_-_191397026 1.401 ENSMUST00000067976.3
Ppp2r5a
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
chr17_-_12507704 1.390 ENSMUST00000024595.2
Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr8_+_124023394 1.371 ENSMUST00000034457.8
Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr10_+_127677064 1.321 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194

transmembrane protein 194

chr2_+_101678403 1.320 ENSMUST00000004949.7
Traf6
TNF receptor-associated factor 6
chr12_+_99884498 1.270 ENSMUST00000153627.1
Tdp1
tyrosyl-DNA phosphodiesterase 1
chr17_-_66101466 1.265 ENSMUST00000024909.8
ENSMUST00000147484.1
ENSMUST00000143987.1
Ndufv2


NADH dehydrogenase (ubiquinone) flavoprotein 2


chr2_+_126152141 1.222 ENSMUST00000170908.1
Dtwd1
DTW domain containing 1
chr19_-_5366626 1.181 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr11_+_16951371 1.162 ENSMUST00000109635.1
ENSMUST00000061327.1
Fbxo48

F-box protein 48

chr6_-_148831395 1.089 ENSMUST00000145960.1
Ipo8
importin 8
chr7_-_109865586 1.076 ENSMUST00000007423.5
ENSMUST00000106728.2
ENSMUST00000106729.1
Scube2


signal peptide, CUB domain, EGF-like 2


chr2_+_181319806 1.072 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr17_-_28350747 1.067 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr2_-_3512746 1.005 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr3_-_142881942 0.985 ENSMUST00000043812.8
Pkn2
protein kinase N2
chr16_+_90727490 0.982 ENSMUST00000181232.1
Gm17518
predicted gene, 17518
chr2_+_181319714 0.917 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr5_+_88764983 0.909 ENSMUST00000031311.9
Dck
deoxycytidine kinase
chr12_+_9029982 0.906 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr9_-_123678782 0.904 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr5_-_138171813 0.900 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr10_-_117792663 0.880 ENSMUST00000167943.1
ENSMUST00000064848.5
Nup107

nucleoporin 107

chr1_-_151500794 0.861 ENSMUST00000076110.4
Rnf2
ring finger protein 2
chr9_-_65580040 0.829 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr4_-_3835595 0.805 ENSMUST00000138502.1
Rps20
ribosomal protein S20
chr10_-_91123955 0.804 ENSMUST00000164505.1
ENSMUST00000170810.1
ENSMUST00000076694.6
Slc25a3


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3


chr4_+_108834601 0.774 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr13_+_23535411 0.773 ENSMUST00000080859.5
Hist1h3g
histone cluster 1, H3g
chr4_-_59783800 0.747 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr17_-_28350600 0.707 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr5_+_113772748 0.704 ENSMUST00000026937.5
ENSMUST00000112311.1
ENSMUST00000112312.1
Iscu


IscU iron-sulfur cluster scaffold homolog (E. coli)


chr1_-_179803625 0.681 ENSMUST00000027768.7
Ahctf1
AT hook containing transcription factor 1
chr2_-_62646146 0.656 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr17_+_34981847 0.577 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_-_4397052 0.575 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr9_-_32344237 0.566 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr12_+_106010263 0.565 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
Vrk1


vaccinia related kinase 1


chr17_+_86753900 0.564 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr9_+_57708534 0.495 ENSMUST00000043990.7
ENSMUST00000142807.1
Edc3

enhancer of mRNA decapping 3 homolog (S. cerevisiae)

chrY_-_90754821 0.472 ENSMUST00000177893.1
Gm21860
predicted gene, 21860
chr1_+_120340569 0.462 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr6_+_70726430 0.448 ENSMUST00000103410.1
Igkc
immunoglobulin kappa constant
chr17_-_57031468 0.428 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr4_-_132463873 0.410 ENSMUST00000102567.3
Med18
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr15_-_38078842 0.368 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_69974367 0.353 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr5_+_130257029 0.352 ENSMUST00000100662.3
ENSMUST00000040213.6
Tyw1

tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

chr19_+_46003468 0.332 ENSMUST00000099393.2
Hps6
Hermansky-Pudlak syndrome 6
chr7_-_16286010 0.327 ENSMUST00000145519.2
Ccdc9
coiled-coil domain containing 9
chr11_+_119602981 0.278 ENSMUST00000026671.6
Rptor
regulatory associated protein of MTOR, complex 1
chr19_+_46075842 0.265 ENSMUST00000165017.1
Nolc1
nucleolar and coiled-body phosphoprotein 1
chr3_+_121953213 0.225 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr7_+_24884611 0.208 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr6_+_37870786 0.197 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr1_+_86303221 0.171 ENSMUST00000113306.2
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chrX_+_8271133 0.113 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chrX_+_162901226 0.108 ENSMUST00000101095.2
Ctps2
cytidine 5'-triphosphate synthase 2
chr7_+_24884651 0.103 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr2_-_145935014 0.098 ENSMUST00000001818.4
Crnkl1
Crn, crooked neck-like 1 (Drosophila)
chr13_-_69533839 0.092 ENSMUST00000044081.7
Papd7
PAP associated domain containing 7
chr5_-_112228934 0.077 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr5_-_92348871 0.063 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr17_+_84956718 0.061 ENSMUST00000112305.3
Ppm1b
protein phosphatase 1B, magnesium dependent, beta isoform
chr12_+_4234023 0.023 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.6 7.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
2.0 5.9 GO:0000087 mitotic M phase(GO:0000087)
1.9 7.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.9 5.6 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
1.5 3.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.4 4.1 GO:0000710 meiotic mismatch repair(GO:0000710)
1.3 3.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.3 3.8 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
1.1 7.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.0 3.1 GO:0061144 alveolar secondary septum development(GO:0061144)
1.0 5.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.9 3.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.9 6.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.8 2.5 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.8 4.9 GO:0007144 female meiosis I(GO:0007144)
0.8 5.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.7 2.9 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.7 2.6 GO:0035878 nail development(GO:0035878)
0.6 4.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 1.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.6 4.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 14.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.5 6.8 GO:0070986 left/right axis specification(GO:0070986)
0.5 2.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.5 2.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.5 1.9 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.4 3.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.4 1.3 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.4 3.5 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.4 1.5 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.4 11.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.4 12.3 GO:0006270 DNA replication initiation(GO:0006270)
0.4 2.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.4 5.0 GO:0042640 anagen(GO:0042640)
0.4 2.1 GO:0046909 intermembrane transport(GO:0046909)
0.3 7.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 8.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 7.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 2.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 27.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.3 3.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 2.9 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 2.8 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.3 1.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 3.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.2 1.4 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2 0.9 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 4.4 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 0.7 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.2 2.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 1.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 2.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.2 0.6 GO:0043987 histone-serine phosphorylation(GO:0035404) histone H3-S10 phosphorylation(GO:0043987)
0.2 2.9 GO:0034508 centromere complex assembly(GO:0034508)
0.2 0.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 1.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.2 0.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 2.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 9.1 GO:0007051 spindle organization(GO:0007051)
0.2 2.6 GO:0031297 replication fork processing(GO:0031297)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.6 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 1.8 GO:0033211 leptin-mediated signaling pathway(GO:0033210) adiponectin-activated signaling pathway(GO:0033211)
0.1 1.9 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 5.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.3 GO:0000012 single strand break repair(GO:0000012)
0.1 1.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.9 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 1.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 1.6 GO:0019835 cytolysis(GO:0019835)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.1 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 6.0 GO:0051028 mRNA transport(GO:0051028)
0.1 2.8 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.9 GO:0006284 base-excision repair(GO:0006284)
0.0 2.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 2.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.2 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 1.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 2.4 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 11.7 GO:0031262 Ndc80 complex(GO:0031262)
1.5 8.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 5.7 GO:0031523 Myb complex(GO:0031523)
1.0 10.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.9 7.8 GO:0008278 cohesin complex(GO:0008278)
0.8 3.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 3.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 2.9 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.6 4.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.6 2.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 4.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 4.1 GO:0032300 mismatch repair complex(GO:0032300)
0.4 2.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 6.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 3.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 3.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 4.9 GO:0042555 MCM complex(GO:0042555)
0.3 1.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 4.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 20.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.3 1.9 GO:0005638 lamin filament(GO:0005638)
0.3 2.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.6 GO:0030056 hemidesmosome(GO:0030056)
0.2 5.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 9.5 GO:0005882 intermediate filament(GO:0005882)
0.2 1.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 1.5 GO:0034709 methylosome(GO:0034709)
0.2 4.3 GO:0051233 spindle midzone(GO:0051233)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 5.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.0 GO:0030894 replisome(GO:0030894)
0.1 9.1 GO:0000922 spindle pole(GO:0000922)
0.1 7.8 GO:0005643 nuclear pore(GO:0005643)
0.1 1.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 6.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 10.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 3.3 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 6.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 12.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.6 GO:0043197 dendritic spine(GO:0043197)
0.0 3.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.5 4.5 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.4 4.1 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
1.3 7.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.8 5.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8 7.9 GO:0070700 BMP receptor binding(GO:0070700)
0.7 5.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 2.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.6 1.9 GO:0000405 bubble DNA binding(GO:0000405)
0.5 2.6 GO:0038132 neuregulin binding(GO:0038132)
0.5 3.6 GO:0000150 recombinase activity(GO:0000150)
0.5 1.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.5 3.0 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.5 1.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.5 1.8 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.4 5.3 GO:0036310 annealing helicase activity(GO:0036310)
0.4 2.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 4.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 4.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4 2.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 3.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.3 2.5 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.3 4.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 7.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 0.8 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.2 2.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 0.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 2.2 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.2 8.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.2 0.6 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.2 3.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 5.9 GO:0050699 WW domain binding(GO:0050699)
0.2 3.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 1.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 3.8 GO:0005112 Notch binding(GO:0005112)
0.1 1.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 5.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 1.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 3.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.7 GO:0016208 AMP binding(GO:0016208)
0.1 1.9 GO:0043274 phospholipase binding(GO:0043274)
0.1 2.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.3 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.0 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0 0.6 GO:0050897 cobalt ion binding(GO:0050897)
0.0 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.9 GO:0045502 dynein binding(GO:0045502)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 7.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.0 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 4.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 5.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)