Motif ID: Ebf3

Z-value: 1.182


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_1373144450.232.0e-01Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_117781017 7.746 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr15_-_66812593 7.180 ENSMUST00000100572.3
 Sla
src-like adaptor
chr11_-_98329641 6.838 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr1_-_56969827 5.515 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 5.359 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr6_-_32588192 5.192 ENSMUST00000115096.2
 Plxna4
plexin A4
chr4_-_129121234 4.943 ENSMUST00000030572.3
 Hpca
hippocalcin
chr4_-_129121699 4.943 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr2_+_55437100 4.849 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr11_+_104231390 4.493 ENSMUST00000106992.3
 Mapt
microtubule-associated protein tau
chr5_+_135806859 4.422 ENSMUST00000126232.1
 Srrm3
serine/arginine repetitive matrix 3
chr11_-_98053415 4.322 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr11_+_104231573 4.229 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr18_-_31447383 4.151 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr11_+_104231515 3.928 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr4_+_101496648 3.914 ENSMUST00000106930.1
ENSMUST00000154120.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr1_-_173367638 3.739 ENSMUST00000005470.4
ENSMUST00000111220.1
 Cadm3

cell adhesion molecule 3

chr15_+_99224976 3.715 ENSMUST00000041415.3
 Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_+_104231465 3.709 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr7_-_4546567 3.634 ENSMUST00000065957.5
 Syt5
synaptotagmin V

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 124 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 16.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.7 10.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
3.3 9.9 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.9 7.7 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 7.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 7.3 GO:0010107 potassium ion import(GO:0010107)
2.3 6.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 5.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.7 5.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.3 5.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.5 4.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 4.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.7 3.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 3.8 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.6 3.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 3.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.4 3.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.7 3.0 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 3.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 2.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 16.4 GO:0045298 tubulin complex(GO:0045298)
1.0 9.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 8.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 7.8 GO:0031045 dense core granule(GO:0031045)
0.7 7.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 7.5 GO:0005768 endosome(GO:0005768)
0.1 7.4 GO:0030315 T-tubule(GO:0030315)
0.0 7.2 GO:0030425 dendrite(GO:0030425)
0.2 6.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 5.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 5.6 GO:0060077 inhibitory synapse(GO:0060077)
0.5 5.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 4.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 4.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.7 GO:0008021 synaptic vesicle(GO:0008021)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.0 3.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.6 GO:0071564 npBAF complex(GO:0071564)
0.0 2.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 2.4 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 14.8 GO:0034185 apolipoprotein binding(GO:0034185)
2.6 7.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.5 7.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 6.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.5 5.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 5.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 5.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 4.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2 4.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 4.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 4.3 GO:0070888 E-box binding(GO:0070888)
0.2 4.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 4.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 4.0 GO:0031005 filamin binding(GO:0031005)
0.6 3.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.6 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 3.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)