Motif ID: Elf1_Elf2_Etv2_Elf4

Z-value: 2.519

Transcription factors associated with Elf1_Elf2_Etv2_Elf4:

Gene SymbolEntrez IDGene Name
Elf1 ENSMUSG00000036461.9 Elf1
Elf2 ENSMUSG00000037174.12 Elf2
Elf4 ENSMUSG00000031103.6 Elf4
Etv2 ENSMUSG00000006311.8 Etv2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf1mm10_v2_chr14_+_79481164_79481194-0.855.4e-10Click!
Elf2mm10_v2_chr3_-_51340628_51340681-0.645.7e-05Click!
Elf4mm10_v2_chrX_-_48454152_484541930.639.3e-05Click!


Activity profile for motif Elf1_Elf2_Etv2_Elf4.

activity profile for motif Elf1_Elf2_Etv2_Elf4


Sorted Z-values histogram for motif Elf1_Elf2_Etv2_Elf4

Sorted Z-values for motif Elf1_Elf2_Etv2_Elf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf1_Elf2_Etv2_Elf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 17.712 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_5845243 12.106 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr9_-_57836706 11.877 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr16_-_22161450 10.676 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_156839790 9.833 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr4_+_124850679 9.772 ENSMUST00000102628.4
 Yrdc
yrdC domain containing (E.coli)
chr11_-_94653964 9.645 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr1_-_180330550 9.118 ENSMUST00000050581.3
 Gm5069
predicted pseudogene 5069
chr3_-_89418287 8.856 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr2_+_5845017 8.543 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr1_+_84839833 8.247 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr7_-_126792469 7.902 ENSMUST00000032936.6
 Ppp4c
protein phosphatase 4, catalytic subunit
chr11_-_69921057 7.835 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr6_+_117906809 7.748 ENSMUST00000177918.1
ENSMUST00000163168.2
 Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr4_-_136053343 7.734 ENSMUST00000102536.4
 Rpl11
ribosomal protein L11
chr9_+_106429399 7.614 ENSMUST00000150576.1
 Rpl29
ribosomal protein L29
chr10_+_79682304 7.447 ENSMUST00000166603.1
 Cdc34
cell division cycle 34
chr9_+_106429537 7.404 ENSMUST00000059802.6
 Rpl29
ribosomal protein L29
chr19_-_4928241 7.351 ENSMUST00000025851.3
 Dpp3
dipeptidylpeptidase 3
chr12_+_109747903 7.276 ENSMUST00000183084.1
ENSMUST00000182300.1
 Mirg

miRNA containing gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,011 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 115.5 GO:0008380 RNA splicing(GO:0008380)
0.6 63.9 GO:0006413 translational initiation(GO:0006413)
1.5 56.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 45.6 GO:0006412 translation(GO:0006412)
2.2 45.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 39.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.5 39.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
1.4 38.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.9 33.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.4 30.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.9 29.5 GO:0006284 base-excision repair(GO:0006284)
0.7 28.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.8 28.0 GO:0002181 cytoplasmic translation(GO:0002181)
1.7 23.5 GO:0010388 cullin deneddylation(GO:0010388)
3.6 21.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 21.8 GO:0051028 mRNA transport(GO:0051028)
0.6 20.7 GO:0032543 mitochondrial translation(GO:0032543)
2.4 19.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.1 18.5 GO:0043248 proteasome assembly(GO:0043248)
1.0 17.2 GO:0045116 protein neddylation(GO:0045116)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 422 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 140.6 GO:0005730 nucleolus(GO:0005730)
1.7 122.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.7 84.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.9 68.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.5 47.5 GO:0005681 spliceosomal complex(GO:0005681)
0.8 38.9 GO:0008180 COP9 signalosome(GO:0008180)
3.0 36.5 GO:0005687 U4 snRNP(GO:0005687)
0.5 33.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
1.0 29.8 GO:0030684 preribosome(GO:0030684)
1.1 29.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 29.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 25.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
3.6 25.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.6 24.1 GO:0042555 MCM complex(GO:0042555)
0.9 24.0 GO:0015030 Cajal body(GO:0015030)
1.7 23.5 GO:0000974 Prp19 complex(GO:0000974)
2.2 21.9 GO:0031595 nuclear proteasome complex(GO:0031595)
2.4 21.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 21.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.4 19.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 597 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 172.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 118.2 GO:0044822 poly(A) RNA binding(GO:0044822)
1.1 74.3 GO:0003743 translation initiation factor activity(GO:0003743)
1.0 60.9 GO:0019843 rRNA binding(GO:0019843)
0.8 47.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.8 41.9 GO:0000049 tRNA binding(GO:0000049)
1.3 37.2 GO:0030515 snoRNA binding(GO:0030515)
1.4 30.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 27.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 27.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.3 27.8 GO:0008173 RNA methyltransferase activity(GO:0008173)
2.9 26.5 GO:1990446 U1 snRNP binding(GO:1990446)
2.9 26.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 25.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.5 24.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
2.9 23.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
2.7 21.8 GO:0003688 DNA replication origin binding(GO:0003688)
2.1 21.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 21.0 GO:0003779 actin binding(GO:0003779)
0.6 20.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)