Motif ID: Elf3

Z-value: 0.997


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.467.2e-03Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_146502141 6.784 ENSMUST00000079573.6
ENSMUST00000139732.1
 Itpr2

inositol 1,4,5-triphosphate receptor 2

chr19_+_25406661 4.561 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr6_-_146502099 3.566 ENSMUST00000053273.8
 Itpr2
inositol 1,4,5-triphosphate receptor 2
chr13_+_13437602 3.489 ENSMUST00000005532.7
 Nid1
nidogen 1
chr18_+_56432116 3.439 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr3_+_90603767 3.231 ENSMUST00000001046.5
ENSMUST00000107330.1
 S100a4

S100 calcium binding protein A4

chr10_+_79988584 3.201 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr10_-_83648713 3.040 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr7_+_101378183 3.039 ENSMUST00000084895.5
 Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_+_115163333 3.032 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr11_-_55419898 2.801 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr14_-_70207637 2.732 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr16_+_62854299 2.571 ENSMUST00000023629.8
 Pros1
protein S (alpha)
chr11_+_53770014 2.463 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
 Irf1


interferon regulatory factor 1


chr4_-_53159885 2.406 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_-_37458523 2.380 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr19_-_50678485 2.330 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr17_+_86753900 2.317 ENSMUST00000024954.9
 Epas1
endothelial PAS domain protein 1
chr11_-_48816936 2.268 ENSMUST00000140800.1
 Trim41
tripartite motif-containing 41
chr8_+_72646679 2.216 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 10.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 6.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.6 4.7 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.9 3.7 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.2 3.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.2 3.5 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.4 3.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 3.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 3.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 3.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
1.0 3.0 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 2.8 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 2.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.3 2.6 GO:0042730 fibrinolysis(GO:0042730)
0.6 2.4 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489) platelet dense granule organization(GO:0060155)
0.0 2.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.6 2.3 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.3 2.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 2.0 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.1 2.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 10.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 4.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 4.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.9 GO:0072562 blood microparticle(GO:0072562)
0.1 3.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 3.5 GO:0005605 basal lamina(GO:0005605)
0.0 3.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.3 GO:0005901 caveola(GO:0005901)
0.5 3.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6 3.0 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.6 1.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 10.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 6.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 4.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 4.5 GO:0017166 vinculin binding(GO:0017166)
0.5 3.5 GO:0043237 laminin-1 binding(GO:0043237)
0.2 3.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.5 3.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.3 3.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 3.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 2.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.8 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 2.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 2.3 GO:0050897 cobalt ion binding(GO:0050897)
0.5 2.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 2.0 GO:0015643 toxic substance binding(GO:0015643)
0.2 2.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.0 GO:0005522 profilin binding(GO:0005522)
0.5 1.9 GO:0035877 death effector domain binding(GO:0035877)