Motif ID: En2

Z-value: 0.515


Transcription factors associated with En2:

Gene SymbolEntrez IDGene Name
En2 ENSMUSG00000039095.7 En2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
En2mm10_v2_chr5_+_28165690_281657170.183.3e-01Click!


Activity profile for motif En2.

activity profile for motif En2


Sorted Z-values histogram for motif En2

Sorted Z-values for motif En2



Network of associatons between targets according to the STRING database.



First level regulatory network of En2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_23574381 4.447 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr5_-_62766153 3.583 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_84417359 2.737 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr17_+_3397189 2.484 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr16_+_38089001 2.090 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr7_+_29071597 1.868 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr12_-_85151264 1.749 ENSMUST00000019379.7
Rps6kl1
ribosomal protein S6 kinase-like 1
chr2_+_116067213 1.746 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr6_-_126645784 1.734 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr16_-_42340595 1.717 ENSMUST00000102817.4
Gap43
growth associated protein 43
chrX_+_136741821 1.432 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr4_+_21848039 1.353 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr19_-_4121536 1.325 ENSMUST00000025767.7
Aip
aryl-hydrocarbon receptor-interacting protein
chr6_+_8948608 1.320 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr15_+_18818895 1.290 ENSMUST00000166873.2
Cdh10
cadherin 10
chr11_+_75532099 1.269 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr14_-_55560340 1.258 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr3_+_96268654 1.239 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr3_+_88207308 1.231 ENSMUST00000180582.1
Gm3764
predicted gene 3764
chr10_+_73821857 1.225 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr13_+_23544052 1.210 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr12_-_84450944 1.202 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr11_-_20332654 1.199 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chrX_-_37110257 1.195 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_-_20332689 1.192 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_+_75531690 1.189 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr2_+_62664279 1.176 ENSMUST00000028257.2
Gca
grancalcin
chr4_-_14621805 1.165 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr7_+_126950518 1.159 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr13_-_23574196 1.127 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chrM_+_10167 1.099 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr2_-_116067391 1.086 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr3_+_76075583 1.080 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr5_+_81021583 1.037 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr4_+_130047840 1.012 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr7_+_126950687 1.004 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr19_-_56822161 0.997 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr16_+_45093611 0.983 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr5_-_106696819 0.981 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr2_-_173276144 0.981 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr12_+_35047180 0.972 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr12_+_52699297 0.960 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr5_-_106696530 0.946 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr5_-_62765618 0.935 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_96719404 0.923 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr5_+_88583527 0.899 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr5_-_77115145 0.887 ENSMUST00000081964.5
Hopx
HOP homeobox
chr2_-_144527341 0.887 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr6_+_125145235 0.875 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr10_+_39612934 0.864 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr3_-_94412883 0.838 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr19_-_28967794 0.830 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr13_+_21717626 0.825 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr8_+_13907748 0.804 ENSMUST00000043520.3
Fbxo25
F-box protein 25
chr10_-_127121125 0.801 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr6_-_146502141 0.773 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr7_+_103550368 0.772 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chrX_-_134111852 0.751 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr3_+_62419668 0.748 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr14_+_55560480 0.747 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr11_+_69059750 0.742 ENSMUST00000051888.2
2310047M10Rik
RIKEN cDNA 2310047M10 gene
chr9_-_96719549 0.719 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr16_-_45724600 0.700 ENSMUST00000096057.4
Tagln3
transgelin 3
chr11_+_75532127 0.688 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr1_-_79440039 0.683 ENSMUST00000049972.4
Scg2
secretogranin II
chr1_-_131527302 0.675 ENSMUST00000097588.2
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_118212715 0.650 ENSMUST00000106302.2
ENSMUST00000151165.1
Cyth1

cytohesin 1

chr4_+_109978004 0.642 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr13_-_47106176 0.625 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chrM_+_7005 0.621 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr7_+_79273201 0.585 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr11_+_69095217 0.577 ENSMUST00000101004.2
Per1
period circadian clock 1
chrX_+_56454871 0.568 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr18_+_42511496 0.567 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr17_+_34039437 0.535 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr8_-_83955205 0.534 ENSMUST00000098595.2
Gm10644
predicted gene 10644
chr18_-_34624562 0.534 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr3_-_94436574 0.527 ENSMUST00000029787.4
Oaz3
ornithine decarboxylase antizyme 3
chr12_-_91849081 0.521 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr14_+_55560904 0.520 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chrX_+_129749740 0.511 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr4_-_24430838 0.503 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chrX_+_75514299 0.496 ENSMUST00000114070.3
ENSMUST00000033540.5
Vbp1

von Hippel-Lindau binding protein 1

chr11_-_71019233 0.455 ENSMUST00000108523.3
ENSMUST00000143850.1
Derl2

Der1-like domain family, member 2

chr1_+_104768510 0.454 ENSMUST00000062528.8
Cdh20
cadherin 20
chr4_+_136310991 0.451 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr4_-_14621494 0.442 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr5_-_131616599 0.442 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr2_+_20737306 0.442 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr4_+_138775735 0.441 ENSMUST00000030528.2
Pla2g2d
phospholipase A2, group IID
chr11_-_70687917 0.438 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr5_-_137684665 0.423 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr11_-_102946688 0.417 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr19_+_4878671 0.415 ENSMUST00000006632.7
Zdhhc24
zinc finger, DHHC domain containing 24
chr18_+_37300799 0.413 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr12_+_24651346 0.412 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr19_-_6942406 0.405 ENSMUST00000099782.3
Gpr137
G protein-coupled receptor 137
chrM_+_11734 0.397 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr11_-_70688097 0.393 ENSMUST00000108544.1
Camta2
calmodulin binding transcription activator 2
chr12_+_102128718 0.391 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_+_116843278 0.391 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr4_+_136310952 0.388 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr8_-_70139197 0.377 ENSMUST00000075724.7
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr4_+_136310936 0.368 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr15_+_21111452 0.349 ENSMUST00000075132.6
Cdh12
cadherin 12
chr8_-_84662841 0.343 ENSMUST00000060427.4
Ier2
immediate early response 2
chr7_+_25681158 0.342 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr2_+_25372315 0.341 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr11_+_102285161 0.329 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr14_+_53324632 0.328 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chrM_+_9870 0.325 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr7_+_64501687 0.324 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_-_4778141 0.323 ENSMUST00000094892.5
Il11
interleukin 11
chr18_+_23415400 0.323 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chrM_+_3906 0.312 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr17_+_45734506 0.312 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr5_-_74531619 0.304 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2



Sec1 family domain containing 2



chrM_+_2743 0.296 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr8_+_4238733 0.295 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr17_-_29007925 0.292 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr9_-_71163224 0.290 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr4_+_116221633 0.289 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_+_103133333 0.286 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr11_-_86993682 0.282 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr13_+_5861489 0.271 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr2_-_146511899 0.267 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr1_+_132298606 0.265 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr10_-_109010955 0.265 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr2_+_144527718 0.255 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr8_-_83594440 0.252 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr4_+_42949814 0.249 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr3_+_61364507 0.247 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr14_+_55559993 0.234 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chrM_+_7759 0.232 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_-_83594405 0.228 ENSMUST00000163837.1
Tecr
trans-2,3-enoyl-CoA reductase
chr11_+_103133303 0.220 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr12_+_72441852 0.215 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr7_+_64501949 0.213 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_+_118861954 0.208 ENSMUST00000028807.5
Ivd
isovaleryl coenzyme A dehydrogenase
chr11_-_107337556 0.205 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr18_+_38993126 0.203 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr11_+_23306910 0.201 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr12_+_38780817 0.188 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr8_+_95081187 0.182 ENSMUST00000034239.7
Katnb1
katanin p80 (WD40-containing) subunit B 1
chr3_-_116253467 0.179 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr4_-_155056784 0.169 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr7_-_25754701 0.160 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr14_+_55560010 0.156 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr1_+_66468364 0.156 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr3_-_146682410 0.152 ENSMUST00000124931.1
ENSMUST00000147113.1
Samd13

sterile alpha motif domain containing 13

chrX_-_157415286 0.152 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr1_+_127729405 0.150 ENSMUST00000038006.6
Acmsd
amino carboxymuconate semialdehyde decarboxylase
chr7_+_44590886 0.148 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr7_-_30559600 0.145 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr11_+_23306884 0.143 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr12_+_84451485 0.131 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr13_-_113663670 0.130 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr17_+_20945311 0.126 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr15_+_100334929 0.113 ENSMUST00000075420.4
Mettl7a3
methyltransferase like 7A3
chr9_+_32116040 0.110 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr8_+_4238815 0.108 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr17_-_36032682 0.107 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr12_+_38780284 0.106 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr11_-_109611417 0.106 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chrX_-_57338598 0.102 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr7_-_105399991 0.095 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr7_+_64502090 0.095 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr16_+_22857845 0.080 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
Dnajb11


DnaJ (Hsp40) homolog, subfamily B, member 11


chr14_+_79515618 0.077 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr12_+_72441933 0.077 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr3_-_79841729 0.075 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr16_+_8830093 0.073 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr5_-_137531204 0.072 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr1_-_132390301 0.065 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr10_+_26772477 0.059 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr19_+_3851797 0.059 ENSMUST00000072055.6
Chka
choline kinase alpha
chr1_-_172632931 0.055 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr11_+_115187481 0.053 ENSMUST00000100235.2
ENSMUST00000061450.6
Tmem104

transmembrane protein 104

chr3_+_94413244 0.038 ENSMUST00000166032.1
ENSMUST00000045245.5
Tdrkh

tudor and KH domain containing protein

chr1_+_110099295 0.037 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr3_-_141982224 0.036 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr2_+_152754156 0.033 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr18_-_80986578 0.028 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr9_-_66514567 0.017 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr19_+_6942501 0.010 ENSMUST00000113423.3
Bad
BCL2-associated agonist of cell death
chr11_+_120467635 0.007 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.6 1.7 GO:0050975 sensory perception of touch(GO:0050975)
0.4 1.3 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 1.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 2.4 GO:0015808 L-alanine transport(GO:0015808)
0.3 2.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 1.0 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 1.5 GO:0019532 oxalate transport(GO:0019532)
0.2 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.7 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.8 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.2 0.5 GO:0060023 soft palate development(GO:0060023)
0.2 0.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.9 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.2 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.7 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.1 0.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.2 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.6 GO:0032570 response to progesterone(GO:0032570)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 1.0 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 3.1 GO:0015807 L-amino acid transport(GO:0015807)
0.0 1.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 3.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.5 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.6 GO:0071437 invadopodium(GO:0071437)
0.2 2.1 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.7 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 3.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.9 GO:0070469 respiratory chain(GO:0070469)
0.0 2.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0036004 GAF domain binding(GO:0036004)
0.3 2.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 2.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.3 1.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 0.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.1 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 2.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 3.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 4.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 2.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)