Motif ID: Ep300

Z-value: 0.492


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_815862500.202.6e-01Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_102658640 1.650 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_84800344 1.424 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr14_-_25903100 1.069 ENSMUST00000052286.8
 Plac9a
placenta specific 9a
chr14_-_25902474 1.009 ENSMUST00000183431.1
ENSMUST00000183725.1
 Plac9a

placenta specific 9a

chr12_+_84009481 0.946 ENSMUST00000168120.1
 Acot1
acyl-CoA thioesterase 1
chr2_+_102659213 0.918 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_163602331 0.831 ENSMUST00000152135.1
 Ttpal
tocopherol (alpha) transfer protein-like
chr16_+_93683184 0.822 ENSMUST00000039620.6
 Cbr3
carbonyl reductase 3
chr3_+_90537242 0.783 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr8_+_22757744 0.775 ENSMUST00000033941.5
 Plat
plasminogen activator, tissue
chr9_-_29411736 0.768 ENSMUST00000115236.1
 Ntm
neurotrimin
chr3_+_90537306 0.767 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr10_-_59221757 0.766 ENSMUST00000165971.1
 Sept10
septin 10
chr7_+_96522342 0.759 ENSMUST00000129737.1
 Tenm4
teneurin transmembrane protein 4
chr10_+_58813359 0.750 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr10_-_63244135 0.684 ENSMUST00000054837.3
 1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr10_+_59221945 0.680 ENSMUST00000182161.1
 Sowahc
sosondowah ankyrin repeat domain family member C
chr12_-_69372443 0.676 ENSMUST00000053451.1
 Gm9887
predicted gene 9887
chr8_+_112570043 0.653 ENSMUST00000034225.6
ENSMUST00000118171.1
 Cntnap4

contactin associated protein-like 4

chr1_-_91459254 0.644 ENSMUST00000069620.8
 Per2
period circadian clock 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.6 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 0.8 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 0.8 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.8 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 0.6 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0 0.6 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.0 GO:1990393 3M complex(GO:1990393)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.5 GO:0008061 chitin binding(GO:0008061)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)