Motif ID: Epas1_Bcl3

Z-value: 1.651

Transcription factors associated with Epas1_Bcl3:

Gene SymbolEntrez IDGene Name
Bcl3 ENSMUSG00000053175.10 Bcl3
Epas1 ENSMUSG00000024140.9 Epas1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_867539140.713.7e-06Click!


Activity profile for motif Epas1_Bcl3.

activity profile for motif Epas1_Bcl3


Sorted Z-values histogram for motif Epas1_Bcl3

Sorted Z-values for motif Epas1_Bcl3



Network of associatons between targets according to the STRING database.



First level regulatory network of Epas1_Bcl3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_80802789 15.927 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr10_+_127725392 13.233 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr5_-_134747241 10.896 ENSMUST00000015138.9
 Eln
elastin
chr3_+_105452326 9.326 ENSMUST00000098761.3
 Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr16_-_38713235 8.703 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr12_-_67221221 8.245 ENSMUST00000178814.1
ENSMUST00000179345.2
 Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr12_-_14152038 8.215 ENSMUST00000020926.6
 Fam84a
family with sequence similarity 84, member A
chr9_-_40346290 7.933 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr4_+_48045144 7.883 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr15_+_81936911 7.438 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr9_-_29963112 7.339 ENSMUST00000075069.4
 Ntm
neurotrimin
chr4_-_20778527 7.326 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr19_+_8664005 7.157 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr1_+_152399824 6.885 ENSMUST00000044311.8
 Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr3_-_108017806 6.705 ENSMUST00000126593.1
 Gstm1
glutathione S-transferase, mu 1
chr17_+_86167777 6.516 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr5_-_9725305 6.404 ENSMUST00000004076.3
 Grm3
glutamate receptor, metabotropic 3
chr19_+_23758819 6.301 ENSMUST00000025830.7
 Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr18_-_25753852 5.854 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr1_+_75507077 5.841 ENSMUST00000037330.4
 Inha
inhibin alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 13.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.6 12.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 10.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 10.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
1.3 9.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.9 9.3 GO:0071435 potassium ion export(GO:0071435)
0.3 8.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
2.6 7.9 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.2 7.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 7.4 GO:0060074 synapse maturation(GO:0060074)
0.1 6.7 GO:0006749 glutathione metabolic process(GO:0006749)
1.6 6.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 6.5 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 6.4 GO:0006397 mRNA processing(GO:0006397)
1.1 6.3 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.4 6.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 5.9 GO:0051291 protein heterooligomerization(GO:0051291)
0.3 5.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.1 5.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.7 5.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 23.1 GO:0032279 asymmetric synapse(GO:0032279)
0.1 13.5 GO:0030027 lamellipodium(GO:0030027)
0.1 11.9 GO:0070382 exocytic vesicle(GO:0070382)
0.1 11.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 11.4 GO:0005802 trans-Golgi network(GO:0005802)
3.6 10.9 GO:0071953 elastic fiber(GO:0071953)
0.3 9.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.5 6.4 GO:0097449 astrocyte projection(GO:0097449)
0.1 6.4 GO:0042734 presynaptic membrane(GO:0042734)
2.1 6.3 GO:0043512 inhibin A complex(GO:0043512)
0.0 6.0 GO:0043209 myelin sheath(GO:0043209)
0.4 5.3 GO:0031143 pseudopodium(GO:0031143)
1.0 5.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 4.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 4.8 GO:0031430 M band(GO:0031430)
0.1 4.7 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.5 GO:0033268 node of Ranvier(GO:0033268)
1.1 4.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7 4.4 GO:0008091 spectrin(GO:0008091)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 16.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 10.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 10.8 GO:0015459 potassium channel regulator activity(GO:0015459)
1.9 9.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 9.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 9.1 GO:0017124 SH3 domain binding(GO:0017124)
0.5 8.6 GO:0001223 transcription coactivator binding(GO:0001223)
1.2 7.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 7.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.6 6.7 GO:0016151 nickel cation binding(GO:0016151)
1.6 6.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.6 6.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.7 6.3 GO:0034711 inhibin binding(GO:0034711)
0.2 6.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 6.2 GO:0005272 sodium channel activity(GO:0005272)
0.9 5.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 5.4 GO:0045499 chemorepellent activity(GO:0045499)
1.8 5.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 5.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.7 5.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)