Motif ID: Esrrg

Z-value: 0.380


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187609028_1876090470.271.3e-01Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 177 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_107517321 1.152 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr8_+_70863127 0.782 ENSMUST00000050921.2
 A230052G05Rik
RIKEN cDNA A230052G05 gene
chr18_+_77185815 0.777 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr4_+_13751297 0.760 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_45268876 0.722 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr17_-_81649607 0.632 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr2_+_29965560 0.623 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
 Sptan1





spectrin alpha, non-erythrocytic 1





chr11_-_97573929 0.618 ENSMUST00000126287.1
ENSMUST00000107590.1
 Srcin1

SRC kinase signaling inhibitor 1

chr10_-_84440591 0.538 ENSMUST00000020220.8
 Nuak1
NUAK family, SNF1-like kinase, 1
chr5_+_123343834 0.526 ENSMUST00000120593.1
 Bcl7a
B cell CLL/lymphoma 7A
chr12_+_61523889 0.526 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr19_-_43524462 0.513 ENSMUST00000026196.7
 Got1
glutamate oxaloacetate transaminase 1, soluble
chr16_+_21891969 0.499 ENSMUST00000042065.6
 Map3k13
mitogen-activated protein kinase kinase kinase 13
chr4_-_82505707 0.491 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr2_-_130839683 0.486 ENSMUST00000119422.1
 4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr18_-_43438280 0.464 ENSMUST00000121805.1
 Dpysl3
dihydropyrimidinase-like 3
chr16_+_10545390 0.436 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
 Clec16a


C-type lectin domain family 16, member A


chr11_+_98741805 0.430 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr7_-_141429351 0.420 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr10_+_80148263 0.395 ENSMUST00000099492.3
ENSMUST00000042057.5
 Midn

midnolin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 0.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.8 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.2 0.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.2 0.6 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.0 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 0.5 GO:0006533 aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.1 0.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0042713 negative regulation of urine volume(GO:0035811) sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.2 0.6 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.6 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.2 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)