Motif ID: Ets1

Z-value: 0.802


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_32696121-0.271.3e-01Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 4.365 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr7_+_44850393 4.147 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr6_+_5725639 3.987 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr2_-_156312470 3.863 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr2_-_156392829 3.058 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr6_+_5725812 3.011 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr3_-_89245159 2.819 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr5_+_111733924 2.654 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr3_-_89245005 2.634 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr8_-_71723308 2.559 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr3_-_80802789 2.530 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr18_-_34931931 2.488 ENSMUST00000180351.1
Etf1
eukaryotic translation termination factor 1
chr14_-_19977249 2.432 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_156312299 2.201 ENSMUST00000037096.2
Cnbd2
cyclic nucleotide binding domain containing 2
chr15_-_66812593 2.198 ENSMUST00000100572.3
Sla
src-like adaptor
chr2_+_136713444 2.153 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr3_+_82358056 2.041 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr3_+_28263205 2.039 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr7_-_4546567 2.022 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr11_-_48817332 1.986 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 335 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.6 GO:0060074 synapse maturation(GO:0060074)
0.1 6.2 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.5 5.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 4.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 4.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 3.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.5 3.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 2.8 GO:0006266 DNA ligation(GO:0006266)
0.1 2.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6 2.5 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.4 2.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 2.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 2.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 2.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 2.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.2 2.1 GO:0071569 protein ufmylation(GO:0071569)
0.1 2.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 2.0 GO:0072583 clathrin-mediated endocytosis(GO:0072583)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 6.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 4.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.0 GO:0005776 autophagosome(GO:0005776)
0.0 3.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.2 3.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 3.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.8 3.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 2.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.7 GO:0030018 Z disc(GO:0030018)
0.2 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.5 GO:0070469 respiratory chain(GO:0070469)
0.5 2.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.2 2.2 GO:0031209 SCAR complex(GO:0031209)
0.2 2.1 GO:0071439 clathrin complex(GO:0071439)
0.3 2.0 GO:0000235 astral microtubule(GO:0000235)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 193 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 7.0 GO:0045503 dynein light chain binding(GO:0045503)
0.1 6.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 5.9 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.3 5.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 3.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.1 3.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 3.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 3.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) phospholipase C activity(GO:0004629) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2 2.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842) ubiquitin-like protein transferase activity(GO:0019787)
0.6 2.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 2.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.5 GO:0030552 cAMP binding(GO:0030552)
0.1 2.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)