Motif ID: Ets2

Z-value: 1.321


Transcription factors associated with Ets2:

Gene SymbolEntrez IDGene Name
Ets2 ENSMUSG00000022895.8 Ets2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets2mm10_v2_chr16_+_95702044_957020940.067.5e-01Click!


Activity profile for motif Ets2.

activity profile for motif Ets2


Sorted Z-values histogram for motif Ets2

Sorted Z-values for motif Ets2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156392829 8.634 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr17_+_3397189 8.317 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr6_+_5725639 7.544 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_+_185454803 7.175 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr13_-_59823072 7.000 ENSMUST00000071703.4
 Zcchc6
zinc finger, CCHC domain containing 6
chr3_-_80802789 6.509 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr15_-_66969616 6.345 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr7_+_44850393 5.999 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr4_+_128058962 5.974 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chrX_+_170009659 5.682 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr9_-_29411736 5.465 ENSMUST00000115236.1
 Ntm
neurotrimin
chr5_+_111733924 5.393 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr6_+_5725812 5.265 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chrX_+_170009892 4.956 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chrX_+_163908982 4.940 ENSMUST00000069041.8
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_-_4546567 4.679 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr10_-_83648713 4.627 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr11_+_70647258 4.607 ENSMUST00000037534.7
 Rnf167
ring finger protein 167
chr2_-_5714490 4.544 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr12_-_64965496 4.348 ENSMUST00000021331.7
 Klhl28
kelch-like 28

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 168 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 24.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.3 13.9 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.3 13.2 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.5 7.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.8 7.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.8 6.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 6.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 6.2 GO:0043087 regulation of GTPase activity(GO:0043087)
0.2 6.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
1.0 5.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4 5.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 5.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.3 5.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 5.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.5 5.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 5.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 5.2 GO:0015914 phospholipid transport(GO:0015914)
1.3 5.0 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.2 5.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.6 4.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.5 13.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 12.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 8.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 6.8 GO:0031430 M band(GO:0031430)
0.2 6.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 6.1 GO:0032279 asymmetric synapse(GO:0032279)
0.5 6.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 5.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 5.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 5.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.6 5.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 5.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 4.8 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 4.7 GO:0031045 dense core granule(GO:0031045)
0.4 4.5 GO:0071439 clathrin complex(GO:0071439)
0.7 4.3 GO:0000235 astral microtubule(GO:0000235)
0.1 4.3 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 19.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 13.4 GO:0008565 protein transporter activity(GO:0008565)
2.6 12.8 GO:0045503 dynein light chain binding(GO:0045503)
0.0 12.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 11.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 10.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 9.8 GO:0030276 clathrin binding(GO:0030276)
0.1 9.4 GO:0017124 SH3 domain binding(GO:0017124)
0.2 6.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 6.7 GO:0045296 cadherin binding(GO:0045296)
1.1 6.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.3 6.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 5.2 GO:0051787 misfolded protein binding(GO:0051787)
1.3 5.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 5.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 4.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 4.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 4.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.7 4.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 3.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)