Motif ID: Etv1_Etv5_Gabpa

Z-value: 2.025

Transcription factors associated with Etv1_Etv5_Gabpa:

Gene SymbolEntrez IDGene Name
Etv1 ENSMUSG00000004151.10 Etv1
Etv5 ENSMUSG00000013089.9 Etv5
Gabpa ENSMUSG00000008976.10 Gabpa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gabpamm10_v2_chr16_+_84835070_84835124-0.818.1e-09Click!
Etv1mm10_v2_chr12_+_38783503_38783527-0.771.3e-07Click!
Etv5mm10_v2_chr16_-_22439719_22439733-0.713.9e-06Click!


Activity profile for motif Etv1_Etv5_Gabpa.

activity profile for motif Etv1_Etv5_Gabpa


Sorted Z-values histogram for motif Etv1_Etv5_Gabpa

Sorted Z-values for motif Etv1_Etv5_Gabpa



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv1_Etv5_Gabpa

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_57836706 14.356 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr16_-_22161450 10.758 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_5845243 10.561 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_-_94653964 9.220 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr7_-_126792469 8.524 ENSMUST00000032936.6
 Ppp4c
protein phosphatase 4, catalytic subunit
chr2_+_5845017 7.878 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr4_+_124714776 7.569 ENSMUST00000030734.4
 Sf3a3
splicing factor 3a, subunit 3
chr14_-_31494992 7.380 ENSMUST00000055303.3
 Mettl6
methyltransferase like 6
chr11_+_101733011 7.279 ENSMUST00000129741.1
 Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr6_+_4755327 7.162 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr18_+_36760214 6.979 ENSMUST00000049323.7
 Wdr55
WD repeat domain 55
chr2_+_74825802 6.974 ENSMUST00000028511.7
 Mtx2
metaxin 2
chr17_-_29264115 6.814 ENSMUST00000024802.8
 Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr2_-_130179310 6.784 ENSMUST00000103199.4
 Snrpb
small nuclear ribonucleoprotein B
chr12_+_100110148 6.774 ENSMUST00000021595.8
 Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr4_+_118409331 6.606 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr3_-_129831374 6.588 ENSMUST00000029643.8
 Gar1
GAR1 ribonucleoprotein homolog (yeast)
chr8_+_106893616 6.570 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr4_+_108847827 6.512 ENSMUST00000102738.2
 Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr10_+_75518042 6.372 ENSMUST00000020397.8
 Snrpd3
small nuclear ribonucleoprotein D3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 698 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 79.9 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4 42.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.4 36.2 GO:0006413 translational initiation(GO:0006413)
1.1 34.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
1.3 33.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.9 31.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.6 31.0 GO:0051028 mRNA transport(GO:0051028)
1.0 26.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 24.9 GO:0006412 translation(GO:0006412)
1.4 23.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 20.2 GO:0032543 mitochondrial translation(GO:0032543)
1.8 19.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 19.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
1.4 19.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
2.6 18.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
2.2 17.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.5 17.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.5 17.6 GO:0002181 cytoplasmic translation(GO:0002181)
1.0 16.6 GO:0043248 proteasome assembly(GO:0043248)
1.2 16.2 GO:0010388 cullin deneddylation(GO:0010388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 307 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 91.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 84.6 GO:0005730 nucleolus(GO:0005730)
1.3 62.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 59.1 GO:0030684 preribosome(GO:0030684)
0.8 58.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
2.8 34.0 GO:0005687 U4 snRNP(GO:0005687)
0.6 29.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 28.2 GO:0005667 transcription factor complex(GO:0005667)
2.6 25.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 24.2 GO:0005681 spliceosomal complex(GO:0005681)
0.9 22.4 GO:0015030 Cajal body(GO:0015030)
0.0 21.4 GO:0005739 mitochondrion(GO:0005739)
0.4 21.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.9 18.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.5 18.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.2 17.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.2 17.0 GO:0000974 Prp19 complex(GO:0000974)
1.3 16.1 GO:0005686 U2 snRNP(GO:0005686)
1.0 15.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.4 15.7 GO:0031080 nuclear pore outer ring(GO:0031080)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 415 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 133.9 GO:0044822 poly(A) RNA binding(GO:0044822)
0.6 118.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.9 57.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.8 44.1 GO:0019843 rRNA binding(GO:0019843)
0.5 29.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
1.2 28.0 GO:0030515 snoRNA binding(GO:0030515)
0.3 24.4 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 22.5 GO:0003723 RNA binding(GO:0003723)
0.7 22.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 21.9 GO:0005198 structural molecule activity(GO:0005198)
2.6 21.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
2.7 18.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.6 17.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 17.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 17.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.4 16.2 GO:0000049 tRNA binding(GO:0000049)
2.2 15.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.5 15.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
5.0 15.0 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.7 14.8 GO:0017025 TBP-class protein binding(GO:0017025)