Motif ID: Fli1

Z-value: 1.143


Transcription factors associated with Fli1:

Gene SymbolEntrez IDGene Name
Fli1 ENSMUSG00000016087.7 Fli1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fli1mm10_v2_chr9_-_32541589_32541602-0.441.0e-02Click!


Activity profile for motif Fli1.

activity profile for motif Fli1


Sorted Z-values histogram for motif Fli1

Sorted Z-values for motif Fli1



Network of associatons between targets according to the STRING database.



First level regulatory network of Fli1

PNG image of the network

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Top targets:


Showing 1 to 20 of 142 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_32000452 17.871 ENSMUST00000020537.2
ENSMUST00000109409.1
 Nsg2

neuron specific gene family member 2

chr11_+_32000496 14.480 ENSMUST00000093219.3
 Nsg2
neuron specific gene family member 2
chrX_-_136868537 13.506 ENSMUST00000058814.6
 Rab9b
RAB9B, member RAS oncogene family
chr4_+_43406435 10.038 ENSMUST00000098106.2
ENSMUST00000139198.1
 Rusc2

RUN and SH3 domain containing 2

chr7_-_140082489 7.979 ENSMUST00000026541.7
 Caly
calcyon neuron-specific vesicular protein
chr1_-_126492900 7.821 ENSMUST00000161954.1
 Nckap5
NCK-associated protein 5
chr1_-_175491130 6.798 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr2_+_65845767 5.439 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_+_118478182 5.402 ENSMUST00000111763.1
 Eomes
eomesodermin homolog (Xenopus laevis)
chr6_-_77979515 5.139 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
 Ctnna2


catenin (cadherin associated protein), alpha 2


chr9_+_118478344 5.135 ENSMUST00000035020.8
 Eomes
eomesodermin homolog (Xenopus laevis)
chr1_-_191318090 5.096 ENSMUST00000046770.9
 Nenf
neuron derived neurotrophic factor
chr13_-_51203065 5.076 ENSMUST00000091708.4
 Hist1h2al
histone cluster 1, H2al
chr15_-_76521902 5.072 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr6_-_77979652 5.070 ENSMUST00000161846.1
ENSMUST00000160894.1
 Ctnna2

catenin (cadherin associated protein), alpha 2

chr16_-_42340595 4.588 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr2_+_65845833 4.434 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr5_+_117133567 4.242 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
 Taok3


TAO kinase 3


chr12_+_86678685 3.859 ENSMUST00000021681.3
 Vash1
vasohibin 1
chr10_+_69533761 3.683 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 39.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 13.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
4.4 13.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.9 10.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 10.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 9.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 6.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.3 5.9 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.5 5.1 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 5.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 4.6 GO:0016198 axon choice point recognition(GO:0016198)
0.2 4.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
1.0 3.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 3.9 GO:0007631 feeding behavior(GO:0007631)
0.6 3.8 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.9 3.6 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.2 2.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 2.4 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 2.3 GO:0006821 chloride transport(GO:0006821)
0.1 2.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 42.1 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.2 13.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.6 12.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 9.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 6.8 GO:0044292 dendrite terminus(GO:0044292)
1.1 6.3 GO:0044308 axonal spine(GO:0044308)
0.2 4.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.3 0.8 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.7 40.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 19.5 GO:0045296 cadherin binding(GO:0045296)
0.2 13.5 GO:0019003 GDP binding(GO:0019003)
0.2 13.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 10.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 6.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.9 6.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.8 4.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
1.2 3.6 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.3 3.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 3.3 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.3 2.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 2.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.4 GO:0030553 cGMP binding(GO:0030553)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)