Motif ID: Fos

Z-value: 0.717


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_854738960.163.6e-01Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_126799163 3.469 ENSMUST00000032934.5
 Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126799134 3.419 ENSMUST00000087566.4
 Aldoa
aldolase A, fructose-bisphosphate
chr11_-_102365111 2.870 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chrX_+_96455359 2.865 ENSMUST00000033553.7
 Heph
hephaestin
chr18_+_82910863 2.718 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr7_+_128523576 2.642 ENSMUST00000033136.7
 Bag3
BCL2-associated athanogene 3
chrX_+_164269371 2.605 ENSMUST00000145412.1
ENSMUST00000033749.7
 Pir

pirin

chr13_+_15463837 2.599 ENSMUST00000110510.3
 Gli3
GLI-Kruppel family member GLI3
chrX_-_143827391 2.477 ENSMUST00000087316.5
 Capn6
calpain 6
chr18_+_61045139 2.448 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr5_-_134946917 2.428 ENSMUST00000051401.2
 Cldn4
claudin 4
chr2_+_30078584 2.359 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr18_+_35118880 2.342 ENSMUST00000042345.6
 Ctnna1
catenin (cadherin associated protein), alpha 1
chr7_+_27486910 2.327 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chr12_+_80518990 2.308 ENSMUST00000021558.6
 Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr9_+_78615501 2.279 ENSMUST00000093812.4
 Cd109
CD109 antigen
chr2_+_13573927 2.243 ENSMUST00000141365.1
ENSMUST00000028062.2
 Vim

vimentin

chr16_-_44558864 2.238 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr7_-_45920830 2.010 ENSMUST00000164119.1
 Emp3
epithelial membrane protein 3
chr7_-_144751968 2.001 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 6.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 4.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
1.3 3.8 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 3.0 GO:0032060 bleb assembly(GO:0032060)
0.1 2.9 GO:0006825 copper ion transport(GO:0006825)
0.3 2.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.9 2.6 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.1 2.6 GO:0030224 monocyte differentiation(GO:0030224)
0.1 2.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 2.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 2.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 2.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.8 2.4 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.6 2.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 2.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 2.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 2.3 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.4 2.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 6.4 GO:0005925 focal adhesion(GO:0005925)
0.1 5.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 4.1 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.7 GO:0043235 receptor complex(GO:0043235)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.8 2.3 GO:1990047 spindle matrix(GO:1990047)
0.2 2.3 GO:0005915 zonula adherens(GO:0005915)
0.2 2.3 GO:0031932 TORC2 complex(GO:0031932)
0.6 2.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 2.2 GO:0016592 mediator complex(GO:0016592)
0.1 2.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 1.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 1.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 1.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 6.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 4.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.9 GO:0003924 GTPase activity(GO:0003924)
0.2 3.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 3.5 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.2 3.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 3.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.6 2.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 2.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 2.7 GO:0017166 vinculin binding(GO:0017166)
0.1 2.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.4 2.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.6 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.6 2.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5 2.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 2.3 GO:0050431 transforming growth factor beta binding(GO:0050431)