Motif ID: Fosb

Z-value: 0.496


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.521.9e-03Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_42158092 2.235 ENSMUST00000098122.2
 Gm13306
predicted gene 13306
chr2_+_118663235 2.126 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_+_27622433 1.719 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr14_+_80000292 1.648 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr1_-_12991109 1.369 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr8_-_8639363 1.340 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr6_-_124769548 1.337 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
 Eno2


enolase 2, gamma neuronal


chr11_-_100397740 1.316 ENSMUST00000001592.8
ENSMUST00000107403.1
 Jup

junction plakoglobin

chr11_-_84067063 1.305 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr7_-_4778141 1.300 ENSMUST00000094892.5
 Il11
interleukin 11
chr3_+_55461758 1.285 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr1_+_134560157 1.255 ENSMUST00000047714.7
 Kdm5b
lysine (K)-specific demethylase 5B
chr10_+_26078255 1.232 ENSMUST00000041011.3
 Gm9767
predicted gene 9767
chr1_+_134560190 1.176 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr9_+_104566677 1.146 ENSMUST00000157006.1
 Cpne4
copine IV
chr15_+_102503722 1.007 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr16_+_78930940 0.929 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr2_+_167777467 0.894 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr16_-_4880284 0.893 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr9_-_109059216 0.880 ENSMUST00000112053.1
 Trex1
three prime repair exonuclease 1
chr6_+_17463927 0.858 ENSMUST00000115442.1
 Met
met proto-oncogene
chr1_-_51915968 0.767 ENSMUST00000046390.7
 Myo1b
myosin IB
chr2_+_156475844 0.750 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_-_29253001 0.667 ENSMUST00000071201.4
 Ntng2
netrin G2
chr13_-_113663670 0.663 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr11_-_120630516 0.659 ENSMUST00000106181.1
 Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_-_140774196 0.658 ENSMUST00000026381.6
 Padi4
peptidyl arginine deiminase, type IV
chr6_-_113934679 0.613 ENSMUST00000101044.2
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr9_-_109059711 0.606 ENSMUST00000061973.4
 Trex1
three prime repair exonuclease 1
chr12_-_85288419 0.602 ENSMUST00000121930.1
 Acyp1
acylphosphatase 1, erythrocyte (common) type
chr2_+_156475803 0.583 ENSMUST00000029155.8
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr5_-_21785115 0.553 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
 Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr2_-_151632471 0.544 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
 Snph






syntaphilin






chr7_+_126776939 0.542 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr2_-_18048784 0.504 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr19_+_5447692 0.501 ENSMUST00000025850.5
 Fosl1
fos-like antigen 1
chr11_+_77801325 0.468 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
 Myo18a




myosin XVIIIA




chr11_+_80428598 0.468 ENSMUST00000173938.1
ENSMUST00000017572.7
 Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr6_-_129533267 0.463 ENSMUST00000181594.1
 1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr11_+_77801291 0.460 ENSMUST00000100794.3
 Myo18a
myosin XVIIIA
chr12_+_71015966 0.360 ENSMUST00000046305.5
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr6_+_86849488 0.360 ENSMUST00000089519.6
ENSMUST00000113668.1
 Aak1

AP2 associated kinase 1

chr11_-_69666062 0.353 ENSMUST00000108654.2
ENSMUST00000018918.5
 Cd68

CD68 antigen

chr2_+_143915273 0.347 ENSMUST00000103172.3
 Dstn
destrin
chr3_+_123267445 0.345 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr11_-_50210765 0.326 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chrX_-_75578188 0.326 ENSMUST00000033545.5
 Rab39b
RAB39B, member RAS oncogene family
chr8_+_4226827 0.312 ENSMUST00000053035.6
 Lrrc8e
leucine rich repeat containing 8 family, member E
chr15_-_76014318 0.307 ENSMUST00000060807.5
 Fam83h
family with sequence similarity 83, member H
chr3_+_109573907 0.302 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr3_-_88503187 0.298 ENSMUST00000120377.1
 Lmna
lamin A
chr7_-_127946725 0.295 ENSMUST00000118755.1
ENSMUST00000094026.3
 Prss36

protease, serine, 36

chr9_+_122888471 0.288 ENSMUST00000063980.6
 Zkscan7
zinc finger with KRAB and SCAN domains 7
chr17_-_45592485 0.279 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr12_-_84194007 0.268 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr3_-_88503331 0.264 ENSMUST00000029699.6
 Lmna
lamin A
chr2_-_45110241 0.263 ENSMUST00000177302.1
 Zeb2
zinc finger E-box binding homeobox 2
chr15_-_102257449 0.239 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr17_+_46161021 0.238 ENSMUST00000024748.7
ENSMUST00000172170.1
 Gtpbp2

GTP binding protein 2

chr14_-_55758458 0.213 ENSMUST00000001497.7
 Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr6_+_42349826 0.204 ENSMUST00000070635.6
 Zyx
zyxin
chr14_+_79426454 0.185 ENSMUST00000061222.7
 Kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr13_-_54611274 0.179 ENSMUST00000049575.7
 Cltb
clathrin, light polypeptide (Lcb)
chr17_-_35697971 0.177 ENSMUST00000146472.1
 Ddr1
discoidin domain receptor family, member 1
chr6_+_42350000 0.172 ENSMUST00000164375.1
 Zyx
zyxin
chr11_-_43747963 0.162 ENSMUST00000048578.2
ENSMUST00000109278.1
 Ttc1

tetratricopeptide repeat domain 1

chr1_-_171240055 0.158 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr15_-_102257306 0.156 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr1_+_86064619 0.156 ENSMUST00000027432.8
 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr10_-_86011833 0.151 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr8_+_107293500 0.129 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
 Nfat5


nuclear factor of activated T cells 5


chr17_-_45592262 0.121 ENSMUST00000164769.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr18_+_82910863 0.120 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr12_+_83632208 0.098 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
 Rbm25




RNA binding motif protein 25




chr11_-_96075655 0.096 ENSMUST00000090541.5
 Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr11_-_96075581 0.086 ENSMUST00000107686.1
ENSMUST00000107684.1
 Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr11_-_102365111 0.081 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr13_-_54611332 0.075 ENSMUST00000091609.4
 Cltb
clathrin, light polypeptide (Lcb)
chr2_+_30441831 0.072 ENSMUST00000131476.1
 Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr16_+_20548577 0.071 ENSMUST00000003319.5
 Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chrX_+_73675500 0.064 ENSMUST00000171398.1
 Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_-_133782721 0.059 ENSMUST00000063669.1
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr3_-_88177671 0.040 ENSMUST00000181837.1
 1700113A16Rik
RIKEN cDNA 1700113A16 gene
chr8_+_36489191 0.024 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr10_+_116143881 0.021 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr5_-_86676346 0.017 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr5_-_5265224 0.005 ENSMUST00000115450.1
 Cdk14
cyclin-dependent kinase 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0002159 desmosome assembly(GO:0002159)
0.3 2.4 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.2 0.9 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.2 1.3 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.6 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.6 GO:0048840 otolith development(GO:0048840)
0.1 0.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.0 1.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836) actin filament severing(GO:0051014)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.3 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 2.1 GO:0007613 memory(GO:0007613)
0.0 0.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.3 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 1.6 GO:0042581 specific granule(GO:0042581)
0.1 0.3 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.4 1.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 2.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125) growth factor activity(GO:0008083)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)