Motif ID: Foxa3

Z-value: 0.995


Transcription factors associated with Foxa3:

Gene SymbolEntrez IDGene Name
Foxa3 ENSMUSG00000040891.5 Foxa3



Activity profile for motif Foxa3.

activity profile for motif Foxa3


Sorted Z-values histogram for motif Foxa3

Sorted Z-values for motif Foxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxa3

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 10.170 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr7_+_113765998 6.062 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr15_-_54919961 5.479 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr1_+_51289106 5.122 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr15_+_3270767 5.044 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr15_-_54920115 4.678 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_+_113766119 4.294 ENSMUST00000084696.4
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr2_-_84425258 4.102 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chr7_-_103813913 3.927 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr7_-_103827922 2.962 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr10_+_60106452 2.922 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr11_+_43151599 2.550 ENSMUST00000077659.5
 Atp10b
ATPase, class V, type 10B
chr18_-_62756275 2.462 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr16_+_41532851 2.426 ENSMUST00000078873.4
 Lsamp
limbic system-associated membrane protein
chrX_+_71663665 2.167 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr19_+_20601958 2.133 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr4_+_45965327 2.129 ENSMUST00000107777.2
 Tdrd7
tudor domain containing 7
chr12_-_84450944 2.077 ENSMUST00000085192.5
 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr12_-_56536895 2.030 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr6_-_137571007 2.007 ENSMUST00000100841.2
 Eps8
epidermal growth factor receptor pathway substrate 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 10.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 9.5 GO:0048663 neuron fate commitment(GO:0048663)
0.7 5.0 GO:0001887 selenium compound metabolic process(GO:0001887)
1.0 4.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 4.0 GO:0051028 mRNA transport(GO:0051028)
0.3 3.5 GO:0070842 aggresome assembly(GO:0070842)
0.3 2.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 2.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 2.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.7 2.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.5 2.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 2.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.7 2.0 GO:0021759 globus pallidus development(GO:0021759)
0.5 2.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.9 GO:0097421 liver regeneration(GO:0097421)
0.1 1.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.6 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.2 1.5 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 1.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 11.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 7.8 GO:0005615 extracellular space(GO:0005615)
1.7 6.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.4 GO:0005901 caveola(GO:0005901)
0.0 3.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.3 2.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 2.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 1.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.6 GO:0097433 dense body(GO:0097433)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.1 0.9 GO:0043219 catenin complex(GO:0016342) lateral loop(GO:0043219)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 10.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.7 6.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 5.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 5.0 GO:0008430 selenium binding(GO:0008430)
1.0 4.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.6 2.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 2.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 2.1 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 2.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 1.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.9 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.8 GO:0010181 FMN binding(GO:0010181)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 1.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.5 GO:0070097 delta-catenin binding(GO:0070097)