Motif ID: Foxb1
Z-value: 0.873
Transcription factors associated with Foxb1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Foxb1 | ENSMUSG00000059246.4 | Foxb1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Foxb1 | mm10_v2_chr9_-_69760924_69760940 | -0.46 | 7.5e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 6.7 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
2.1 | 6.3 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
1.0 | 3.8 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
0.8 | 2.4 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.7 | 8.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.7 | 3.6 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.7 | 2.0 | GO:0007525 | somatic muscle development(GO:0007525) |
0.6 | 1.7 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274) |
0.5 | 3.3 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.5 | 1.9 | GO:0007412 | axon target recognition(GO:0007412) |
0.5 | 1.4 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.4 | 1.3 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
0.3 | 2.5 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.3 | 3.6 | GO:0070842 | aggresome assembly(GO:0070842) |
0.2 | 4.5 | GO:0010107 | potassium ion import(GO:0010107) |
0.2 | 2.9 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.2 | 1.8 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 1.7 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 2.6 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 1.1 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 0.5 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
0.1 | 1.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 1.0 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
0.1 | 1.5 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.1 | 0.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.1 | 0.6 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.1 | 2.0 | GO:0007097 | nuclear migration(GO:0007097) |
0.1 | 9.8 | GO:0006342 | chromatin silencing(GO:0006342) |
0.1 | 1.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.1 | 0.7 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.1 | 0.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.1 | 0.8 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.8 | GO:0060746 | parental behavior(GO:0060746) |
0.0 | 0.5 | GO:0060539 | diaphragm development(GO:0060539) |
0.0 | 0.9 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
0.0 | 1.9 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.0 | 1.6 | GO:0051926 | dopamine receptor signaling pathway(GO:0007212) negative regulation of calcium ion transport(GO:0051926) |
0.0 | 0.2 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.0 | 0.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 1.0 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 1.3 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
0.0 | 1.4 | GO:0060349 | bone morphogenesis(GO:0060349) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 8.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.4 | 2.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.3 | 1.8 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.2 | 3.6 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.2 | 6.3 | GO:0030673 | axolemma(GO:0030673) |
0.2 | 3.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.2 | 1.9 | GO:0043083 | synaptic cleft(GO:0043083) |
0.2 | 2.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.1 | 2.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 1.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 5.5 | GO:0030315 | T-tubule(GO:0030315) |
0.1 | 5.9 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 0.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 1.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 3.6 | GO:0044306 | neuron projection terminus(GO:0044306) |
0.0 | 1.3 | GO:0044291 | cell-cell contact zone(GO:0044291) |
0.0 | 6.4 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 2.0 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 8.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.8 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 13.9 | GO:0005794 | Golgi apparatus(GO:0005794) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 11.6 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.9 | 4.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.7 | 6.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.5 | 1.9 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.4 | 2.9 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.4 | 2.4 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.3 | 1.9 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.3 | 9.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.3 | 1.8 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.3 | 1.4 | GO:0071253 | connexin binding(GO:0071253) |
0.3 | 0.8 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
0.3 | 1.6 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.2 | 1.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.2 | 3.6 | GO:0031402 | sodium ion binding(GO:0031402) |
0.2 | 0.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.2 | 1.7 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.1 | 6.7 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 0.7 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.1 | 2.6 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 3.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.1 | 1.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 1.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 2.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.0 | 1.3 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
0.0 | 2.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.8 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 2.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 5.1 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 1.1 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
0.0 | 0.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |