Motif ID: Foxb1

Z-value: 0.873


Transcription factors associated with Foxb1:

Gene SymbolEntrez IDGene Name
Foxb1 ENSMUSG00000059246.4 Foxb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxb1mm10_v2_chr9_-_69760924_69760940-0.467.5e-03Click!


Activity profile for motif Foxb1.

activity profile for motif Foxb1


Sorted Z-values histogram for motif Foxb1

Sorted Z-values for motif Foxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 87 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_123672321 7.311 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr11_-_98329641 6.748 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr16_-_74411292 6.295 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr1_-_72536930 5.911 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr3_-_96240317 4.955 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr3_+_96245530 4.798 ENSMUST00000074976.6
 Hist2h2aa1
histone cluster 2, H2aa1
chr2_+_55437100 4.520 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr3_-_123690806 4.291 ENSMUST00000154668.1
 Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr9_+_53850243 3.838 ENSMUST00000048485.5
 Sln
sarcolipin
chr18_+_36952621 3.827 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2
chr2_-_65529275 3.629 ENSMUST00000126837.1
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_45110336 3.267 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr6_-_56362356 2.944 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
 Pde1c



phosphodiesterase 1C



chr7_+_29071597 2.664 ENSMUST00000180926.1
 Gm26604
predicted gene, 26604
chr10_+_69925766 2.621 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
 Ank3


ankyrin 3, epithelial


chr8_+_66386292 2.567 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr16_-_34095983 2.492 ENSMUST00000114973.1
ENSMUST00000114964.1
 Kalrn

kalirin, RhoGEF kinase

chr3_+_76075583 2.486 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr17_+_70522083 2.410 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr19_-_28911879 2.404 ENSMUST00000179171.1
 AC163993.1
AC163993.1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.8 GO:0006342 chromatin silencing(GO:0006342)
0.7 8.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.2 6.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.1 6.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 4.5 GO:0010107 potassium ion import(GO:0010107)
1.0 3.8 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.7 3.6 GO:0046684 response to pyrethroid(GO:0046684)
0.3 3.6 GO:0070842 aggresome assembly(GO:0070842)
0.5 3.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 2.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.8 2.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.7 2.0 GO:0007525 somatic muscle development(GO:0007525)
0.1 2.0 GO:0007097 nuclear migration(GO:0007097)
0.5 1.9 GO:0007412 axon target recognition(GO:0007412)
0.0 1.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 1.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.6 1.7 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.1 1.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 8.3 GO:0000790 nuclear chromatin(GO:0000790)
0.4 8.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 6.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 6.3 GO:0030673 axolemma(GO:0030673)
0.1 5.9 GO:0005795 Golgi stack(GO:0005795)
0.1 5.5 GO:0030315 T-tubule(GO:0030315)
0.2 3.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 3.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.6 GO:0044306 neuron projection terminus(GO:0044306)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 2.4 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.2 1.9 GO:0043083 synaptic cleft(GO:0043083)
0.3 1.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.3 GO:0044291 cell-cell contact zone(GO:0044291)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 11.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 9.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 6.7 GO:0070888 E-box binding(GO:0070888)
0.7 6.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 5.1 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.9 4.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 3.6 GO:0031402 sodium ion binding(GO:0031402)
0.1 3.3 GO:0070412 R-SMAD binding(GO:0070412)
0.4 2.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 2.4 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.0 GO:0030674 protein binding, bridging(GO:0030674)
0.5 1.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.3 1.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 1.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)