Motif ID: Foxd1

Z-value: 1.607


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_98354250-0.681.5e-05Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 15.822 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr18_+_69344503 12.007 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr4_+_144892813 11.498 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_-_46294592 11.488 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr13_-_93499803 11.139 ENSMUST00000065537.7
 Jmy
junction-mediating and regulatory protein
chr18_-_43059418 10.178 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr6_+_135362931 9.366 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr12_-_100725028 8.996 ENSMUST00000043599.6
 Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr4_+_144893077 8.983 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_-_84978709 8.887 ENSMUST00000064922.5
 Junb
Jun-B oncogene
chr11_+_3332426 8.877 ENSMUST00000136474.1
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr4_+_144893127 8.281 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr16_-_4880284 7.736 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr6_-_5496296 7.697 ENSMUST00000019721.4
 Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr10_+_29211637 7.412 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr11_+_3330781 7.079 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr16_-_74411292 6.655 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr14_-_18239053 6.644 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr7_+_126776939 6.619 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr8_+_65618009 6.548 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
 March1


membrane-associated ring finger (C3HC4) 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 28.8 GO:0042572 retinol metabolic process(GO:0042572)
3.2 22.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.1 15.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 13.3 GO:0045792 negative regulation of cell size(GO:0045792)
1.2 12.0 GO:0042118 endothelial cell activation(GO:0042118)
4.0 11.9 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.5 11.5 GO:0001967 suckling behavior(GO:0001967)
0.7 11.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
2.8 11.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.5 10.2 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.6 9.4 GO:0032060 bleb assembly(GO:0032060)
3.0 9.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.9 8.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
2.6 7.8 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.9 7.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.5 7.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.2 6.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.3 6.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 6.6 GO:2000505 regulation of energy homeostasis(GO:2000505)
2.2 6.5 GO:0019482 beta-alanine metabolic process(GO:0019482)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 26.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 18.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.6 12.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
4.0 11.9 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
2.8 11.2 GO:0044307 dendritic branch(GO:0044307)
1.0 11.0 GO:0031931 TORC1 complex(GO:0031931)
0.2 10.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 10.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 10.5 GO:0031252 cell leading edge(GO:0031252)
0.0 10.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 8.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 7.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 7.3 GO:0016607 nuclear speck(GO:0016607)
0.2 6.7 GO:0030673 axolemma(GO:0030673)
0.1 6.6 GO:0043204 perikaryon(GO:0043204)
0.2 6.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 6.0 GO:0097060 synaptic membrane(GO:0097060)
0.0 5.1 GO:0005769 early endosome(GO:0005769)
0.4 4.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 28.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
7.4 22.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 17.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.8 15.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
3.0 12.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.4 11.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 10.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.7 10.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.6 9.6 GO:0070888 E-box binding(GO:0070888)
0.2 9.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
3.0 9.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
1.4 8.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.8 7.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.9 7.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 6.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 6.6 GO:0005096 GTPase activator activity(GO:0005096)
0.9 6.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 6.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.1 5.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 5.0 GO:0050840 extracellular matrix binding(GO:0050840)