Motif ID: Foxd3

Z-value: 0.518


Transcription factors associated with Foxd3:

Gene SymbolEntrez IDGene Name
Foxd3 ENSMUSG00000067261.3 Foxd3



Activity profile for motif Foxd3.

activity profile for motif Foxd3


Sorted Z-values histogram for motif Foxd3

Sorted Z-values for motif Foxd3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_102010138 2.483 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr8_-_87959560 1.922 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr12_+_111971545 1.537 ENSMUST00000079009.5
 Tdrd9
tudor domain containing 9
chr10_+_11609256 1.472 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr17_+_28691419 1.371 ENSMUST00000124886.1
 Mapk14
mitogen-activated protein kinase 14
chr6_+_38918969 1.290 ENSMUST00000003017.6
 Tbxas1
thromboxane A synthase 1, platelet
chr17_+_29090969 1.287 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_98798653 1.265 ENSMUST00000037930.6
 Msl1
male-specific lethal 1 homolog (Drosophila)
chr10_-_127030789 1.246 ENSMUST00000120547.1
ENSMUST00000152054.1
 Tsfm

Ts translation elongation factor, mitochondrial

chr7_+_67655414 1.242 ENSMUST00000107470.1
 Ttc23
tetratricopeptide repeat domain 23
chr1_+_6734827 1.210 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr4_-_137785371 1.192 ENSMUST00000133473.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr6_-_3494587 1.153 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr17_+_28691342 1.030 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
 Mapk14



mitogen-activated protein kinase 14



chr10_-_127030813 0.990 ENSMUST00000040560.4
 Tsfm
Ts translation elongation factor, mitochondrial
chr9_-_90270712 0.915 ENSMUST00000041767.7
ENSMUST00000144348.1
 Tbc1d2b

TBC1 domain family, member 2B

chr2_-_120539852 0.891 ENSMUST00000171215.1
 Zfp106
zinc finger protein 106
chr2_+_9882622 0.852 ENSMUST00000114919.1
 4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr4_-_36056726 0.848 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr3_+_106034661 0.757 ENSMUST00000170669.2
 Gm4540
predicted gene 4540
chrX_-_163761323 0.677 ENSMUST00000059320.2
 Rnf138rt1
ring finger protein 138, retrogene 1
chr1_+_134415414 0.665 ENSMUST00000112237.1
 Adipor1
adiponectin receptor 1
chr11_-_107189325 0.633 ENSMUST00000018577.7
ENSMUST00000106757.1
 Nol11

nucleolar protein 11

chr9_+_105642957 0.616 ENSMUST00000065778.6
 Pik3r4
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
chr17_+_93199348 0.578 ENSMUST00000064775.6
 Adcyap1
adenylate cyclase activating polypeptide 1
chr5_-_88675190 0.566 ENSMUST00000133532.1
ENSMUST00000150438.1
 Grsf1

G-rich RNA sequence binding factor 1

chr10_-_19011948 0.551 ENSMUST00000105527.1
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr4_-_136898803 0.531 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr2_-_160619971 0.525 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr2_+_52038005 0.509 ENSMUST00000065927.5
 Tnfaip6
tumor necrosis factor alpha induced protein 6
chr19_-_8713862 0.455 ENSMUST00000010239.4
 Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr4_+_108847827 0.443 ENSMUST00000102738.2
 Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr4_+_115737754 0.414 ENSMUST00000106522.2
 Efcab14
EF-hand calcium binding domain 14
chr15_-_98607611 0.414 ENSMUST00000096224.4
 Adcy6
adenylate cyclase 6
chr2_+_181767040 0.411 ENSMUST00000108756.1
 Myt1
myelin transcription factor 1
chr13_-_18031616 0.404 ENSMUST00000099736.2
 Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr6_-_144209471 0.404 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr7_-_99980431 0.400 ENSMUST00000080817.4
 Rnf169
ring finger protein 169
chr5_+_148265307 0.393 ENSMUST00000110514.1
 Mtus2
microtubule associated tumor suppressor candidate 2
chr19_+_8953826 0.380 ENSMUST00000096239.5
 Tut1
terminal uridylyl transferase 1, U6 snRNA-specific
chr5_+_148265202 0.377 ENSMUST00000110515.2
 Mtus2
microtubule associated tumor suppressor candidate 2
chr15_+_100154379 0.372 ENSMUST00000023768.6
ENSMUST00000108971.2
 Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr5_+_148265265 0.365 ENSMUST00000071878.5
 Mtus2
microtubule associated tumor suppressor candidate 2
chr4_-_82850721 0.322 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr2_+_181767283 0.321 ENSMUST00000108757.2
 Myt1
myelin transcription factor 1
chr6_-_144209558 0.313 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr4_+_115737738 0.275 ENSMUST00000106525.2
 Efcab14
EF-hand calcium binding domain 14
chr2_-_172940299 0.273 ENSMUST00000009143.7
 Bmp7
bone morphogenetic protein 7
chr9_+_96258697 0.257 ENSMUST00000179416.1
 Tfdp2
transcription factor Dp 2
chr14_-_52213379 0.214 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr2_+_125136692 0.170 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr10_-_88605017 0.158 ENSMUST00000119185.1
ENSMUST00000121629.1
 Mybpc1

myosin binding protein C, slow-type

chr2_+_152669461 0.144 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
 H13



histocompatibility 13



chr12_-_110840905 0.099 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
 Stk30


serine/threonine kinase 30


chr9_+_36832684 0.083 ENSMUST00000034630.8
 Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chrX_+_164373363 0.076 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr10_+_93488766 0.076 ENSMUST00000129421.1
 Hal
histidine ammonia lyase
chr14_-_45388772 0.074 ENSMUST00000046191.7
 Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr9_+_54980880 0.072 ENSMUST00000093844.3
 Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr6_+_77242715 0.065 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr5_-_120612558 0.047 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
 1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr8_+_46739745 0.029 ENSMUST00000034041.7
 Irf2
interferon regulatory factor 2
chr1_-_126830786 0.023 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr18_-_6516089 0.015 ENSMUST00000115870.2
 Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr6_+_77242644 0.014 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.4 2.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.6 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.2 0.6 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 1.3 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 2.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.7 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 1.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 1.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.3 GO:0072487 MSL complex(GO:0072487)
0.2 1.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 0.6 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.2 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0051525 NFAT protein binding(GO:0051525)
0.3 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.7 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.3 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 1.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)