Motif ID: Foxf1
Z-value: 0.671
Transcription factors associated with Foxf1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Foxf1 | ENSMUSG00000042812.4 | Foxf1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Foxf1 | mm10_v2_chr8_+_121084352_121084474 | -0.47 | 5.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 7.9 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
0.8 | 2.3 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.6 | 2.6 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.6 | 8.3 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.6 | 1.7 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.5 | 1.5 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.5 | 1.4 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.4 | 1.2 | GO:0060160 | musculoskeletal movement, spinal reflex action(GO:0050883) negative regulation of dopamine receptor signaling pathway(GO:0060160) |
0.4 | 3.2 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.3 | 1.0 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.3 | 4.2 | GO:0070842 | aggresome assembly(GO:0070842) |
0.3 | 4.4 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.3 | 6.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.3 | 0.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
0.3 | 0.8 | GO:0007525 | somatic muscle development(GO:0007525) |
0.3 | 0.8 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.3 | 1.5 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.3 | 0.8 | GO:0051464 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) positive regulation of cortisol secretion(GO:0051464) |
0.2 | 0.8 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
0.2 | 0.6 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.2 | 1.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.2 | 0.6 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
0.2 | 1.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.2 | 1.4 | GO:0032264 | IMP salvage(GO:0032264) |
0.2 | 3.6 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.2 | 1.6 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
0.2 | 0.5 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.2 | 0.8 | GO:0071476 | cellular hypotonic response(GO:0071476) |
0.2 | 0.7 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.2 | 0.7 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
0.1 | 0.4 | GO:0009812 | flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696) |
0.1 | 0.6 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
0.1 | 1.0 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.1 | 3.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 1.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 1.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.6 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 0.4 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.1 | 0.7 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
0.1 | 1.0 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 0.9 | GO:0031000 | response to caffeine(GO:0031000) |
0.1 | 1.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.9 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.1 | 0.6 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
0.1 | 2.0 | GO:0007097 | nuclear migration(GO:0007097) |
0.1 | 2.1 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.1 | 0.3 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 1.2 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
0.1 | 0.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 0.6 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
0.1 | 0.7 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.8 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.1 | 0.2 | GO:0046881 | sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
0.1 | 0.6 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
0.1 | 1.8 | GO:0051926 | negative regulation of calcium ion transport(GO:0051926) |
0.1 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 1.9 | GO:0060074 | synapse maturation(GO:0060074) |
0.1 | 0.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.2 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.0 | 0.8 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069) |
0.0 | 1.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 2.0 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.0 | 3.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.2 | GO:0010988 | regulation of low-density lipoprotein particle clearance(GO:0010988) |
0.0 | 1.4 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.2 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.0 | 2.9 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.0 | 0.2 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
0.0 | 0.3 | GO:0030035 | microspike assembly(GO:0030035) |
0.0 | 0.5 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.0 | 3.9 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 2.5 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 1.3 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
0.0 | 2.0 | GO:0021766 | hippocampus development(GO:0021766) |
0.0 | 3.2 | GO:0098792 | xenophagy(GO:0098792) |
0.0 | 0.2 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.1 | GO:0071139 | resolution of recombination intermediates(GO:0071139) |
0.0 | 0.6 | GO:0007340 | acrosome reaction(GO:0007340) |
0.0 | 0.2 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 2.3 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.3 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.0 | 0.1 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.1 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.0 | 0.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.3 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 2.0 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.2 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.7 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 0.3 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.6 | GO:0071437 | invadopodium(GO:0071437) |
0.5 | 8.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.3 | 1.6 | GO:0005901 | caveola(GO:0005901) |
0.3 | 3.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.3 | 2.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.2 | 2.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.2 | 2.9 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.2 | 3.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.2 | 0.7 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.2 | 3.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.8 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.1 | 3.8 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
0.1 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 1.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 0.2 | GO:0070469 | respiratory chain(GO:0070469) |
0.1 | 1.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 1.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 1.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 2.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 1.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.7 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 2.0 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 3.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.0 | 2.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 1.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 7.2 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 2.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.9 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 3.8 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 1.0 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
0.0 | 0.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.2 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.7 | GO:0044291 | cell-cell contact zone(GO:0044291) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.6 | 7.9 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.5 | 4.4 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.5 | 1.5 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.4 | 1.2 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.4 | 2.3 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.3 | 1.0 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.3 | 2.6 | GO:0043495 | protein anchor(GO:0043495) |
0.3 | 2.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.3 | 0.9 | GO:0050827 | toxin receptor binding(GO:0050827) |
0.3 | 1.8 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.2 | 0.8 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.2 | 1.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.2 | 3.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 3.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.1 | 0.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.1 | 0.8 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 4.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.8 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.5 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 0.9 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
0.1 | 1.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 1.4 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 0.8 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 0.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 0.3 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 1.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.1 | 0.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 1.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 1.6 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.1 | 0.3 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.0 | 0.5 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.0 | 1.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.6 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 1.5 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 1.7 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.7 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 2.1 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 0.2 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
0.0 | 0.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.0 | 0.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 1.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.1 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
0.0 | 1.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.1 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.0 | 2.0 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.2 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 4.1 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.2 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |