Motif ID: Foxf2

Z-value: 0.660


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_31625816-0.048.4e-01Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 93 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 6.192 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr15_-_66969616 6.164 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr4_+_101507947 3.076 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 2.844 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_-_148444336 2.483 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr7_-_4844665 2.467 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr14_-_51913393 2.210 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr16_-_4880284 2.129 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr5_+_88583527 2.019 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr12_-_112511136 1.996 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr7_+_45783883 1.952 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_44849581 1.927 ENSMUST00000150335.1
ENSMUST00000107882.1
 Akt1s1

AKT1 substrate 1 (proline-rich)

chr7_+_45783686 1.865 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr16_-_34263179 1.737 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr10_+_40349265 1.660 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr1_+_179546303 1.650 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr7_+_44849216 1.611 ENSMUST00000054343.8
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr1_+_42229726 1.594 ENSMUST00000066196.1
 Gm9915
predicted gene 9915
chr5_-_99252839 1.591 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr2_-_73312701 1.546 ENSMUST00000058615.9
 Cir1
corepressor interacting with RBPJ, 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 6.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.0 5.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 5.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 3.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 3.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 3.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 2.7 GO:0007379 segment specification(GO:0007379)
0.1 2.2 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.3 2.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 2.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 1.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.5 1.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 1.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.4 GO:0050919 negative chemotaxis(GO:0050919)
0.3 1.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.2 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.3 1.0 GO:0002159 desmosome assembly(GO:0002159)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 8.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 4.9 GO:0031931 TORC1 complex(GO:0031931)
0.1 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.3 2.0 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 0.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 0.6 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0005712 chiasma(GO:0005712)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.2 GO:0045296 cadherin binding(GO:0045296)
0.0 5.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 2.1 GO:0097001 ceramide binding(GO:0097001)
0.3 1.6 GO:0071253 connexin binding(GO:0071253)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.0 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)