Motif ID: Foxf2

Z-value: 0.660


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_31625816-0.048.4e-01Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 6.192 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr15_-_66969616 6.164 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr4_+_101507947 3.076 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 2.844 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_-_148444336 2.483 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr7_-_4844665 2.467 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr14_-_51913393 2.210 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr16_-_4880284 2.129 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr5_+_88583527 2.019 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr12_-_112511136 1.996 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr7_+_45783883 1.952 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_44849581 1.927 ENSMUST00000150335.1
ENSMUST00000107882.1
 Akt1s1

AKT1 substrate 1 (proline-rich)

chr7_+_45783686 1.865 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr16_-_34263179 1.737 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr10_+_40349265 1.660 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr1_+_179546303 1.650 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr7_+_44849216 1.611 ENSMUST00000054343.8
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr1_+_42229726 1.594 ENSMUST00000066196.1
 Gm9915
predicted gene 9915
chr5_-_99252839 1.591 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr2_-_73312701 1.546 ENSMUST00000058615.9
 Cir1
corepressor interacting with RBPJ, 1
chr4_-_87806296 1.451 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chrX_+_163911401 1.443 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_44992127 1.390 ENSMUST00000179305.1
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_44848991 1.357 ENSMUST00000107885.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr8_+_93810832 1.249 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr5_-_103211251 1.235 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
 Mapk10



mitogen-activated protein kinase 10



chr4_-_87806276 1.231 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_34262945 1.229 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr8_-_125492710 1.163 ENSMUST00000108775.1
 Sipa1l2
signal-induced proliferation-associated 1 like 2
chr7_+_30291941 1.130 ENSMUST00000144508.1
 Clip3
CAP-GLY domain containing linker protein 3
chr7_-_44849075 1.067 ENSMUST00000047085.8
 Tbc1d17
TBC1 domain family, member 17
chr7_+_82175156 1.052 ENSMUST00000180243.1
 Sh3gl3
SH3-domain GRB2-like 3
chr11_-_100397740 1.044 ENSMUST00000001592.8
ENSMUST00000107403.1
 Jup

junction plakoglobin

chr10_+_60106452 0.996 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr17_+_70522083 0.988 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr8_-_84237042 0.984 ENSMUST00000039480.5
 Zswim4
zinc finger SWIM-type containing 4
chr12_-_15816762 0.978 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr7_+_30291659 0.943 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
 Clip3


CAP-GLY domain containing linker protein 3


chr2_+_28641227 0.910 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
 Tsc1


tuberous sclerosis 1


chr11_+_69095217 0.906 ENSMUST00000101004.2
 Per1
period circadian clock 1
chr12_-_84450944 0.893 ENSMUST00000085192.5
 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr4_-_118409219 0.881 ENSMUST00000075406.5
 Szt2
seizure threshold 2
chr1_-_179546261 0.852 ENSMUST00000027769.5
 Tfb2m
transcription factor B2, mitochondrial
chr2_-_168601620 0.822 ENSMUST00000171689.1
ENSMUST00000137451.1
 Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr2_+_112284561 0.796 ENSMUST00000053666.7
 Slc12a6
solute carrier family 12, member 6
chr13_+_60602182 0.668 ENSMUST00000044083.7
 Dapk1
death associated protein kinase 1
chr8_+_58912257 0.651 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr10_-_49783259 0.613 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr6_-_13677930 0.611 ENSMUST00000045235.5
 B630005N14Rik
RIKEN cDNA B630005N14 gene
chr4_-_82885148 0.610 ENSMUST00000048430.3
 Cer1
cerberus 1 homolog (Xenopus laevis)
chr15_-_98918131 0.608 ENSMUST00000023736.8
 Lmbr1l
limb region 1 like
chr2_+_26973416 0.607 ENSMUST00000014996.7
ENSMUST00000102891.3
 Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr11_-_50210765 0.588 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chr1_-_97977233 0.533 ENSMUST00000161567.1
 Pam
peptidylglycine alpha-amidating monooxygenase
chr17_+_70522149 0.518 ENSMUST00000140728.1
 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr9_-_44802951 0.505 ENSMUST00000044694.6
 Ttc36
tetratricopeptide repeat domain 36
chr1_+_34005872 0.501 ENSMUST00000182296.1
 Dst
dystonin
chr10_-_41303171 0.500 ENSMUST00000043814.3
 Fig4
FIG4 homolog (S. cerevisiae)
chr1_+_43445736 0.486 ENSMUST00000086421.5
ENSMUST00000114744.1
 Nck2

non-catalytic region of tyrosine kinase adaptor protein 2

chr2_+_112265809 0.486 ENSMUST00000110991.2
 Slc12a6
solute carrier family 12, member 6
chr12_+_84451485 0.455 ENSMUST00000137170.1
 Lin52
lin-52 homolog (C. elegans)
chr13_+_46669517 0.426 ENSMUST00000099547.3
 C78339
expressed sequence C78339
chr2_+_176236860 0.426 ENSMUST00000166464.1
 2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr12_-_85270564 0.415 ENSMUST00000019378.6
ENSMUST00000166821.1
 Mlh3

mutL homolog 3 (E coli)

chr7_+_130692532 0.395 ENSMUST00000033141.6
 Tacc2
transforming, acidic coiled-coil containing protein 2
chr3_-_144202300 0.347 ENSMUST00000121796.1
ENSMUST00000121112.1
 Lmo4

LIM domain only 4

chr11_+_118433826 0.333 ENSMUST00000106286.1
 C1qtnf1
C1q and tumor necrosis factor related protein 1
chr2_+_91730127 0.324 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
 Ambra1



autophagy/beclin 1 regulator 1



chr2_-_181578906 0.310 ENSMUST00000136875.1
 Uckl1
uridine-cytidine kinase 1-like 1
chr19_+_7056731 0.284 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr11_-_54956047 0.277 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
 Tnip1


TNFAIP3 interacting protein 1


chr11_+_85311232 0.268 ENSMUST00000020835.9
 Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr7_-_30559828 0.264 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)
chr5_+_118560719 0.256 ENSMUST00000100816.4
 Med13l
mediator complex subunit 13-like
chr10_+_79716588 0.243 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr5_-_115098295 0.231 ENSMUST00000100848.2
 Gm10401
predicted gene 10401
chr16_+_91269759 0.228 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr9_+_70678950 0.173 ENSMUST00000067880.6
 Adam10
a disintegrin and metallopeptidase domain 10
chr12_+_69296676 0.149 ENSMUST00000021362.4
 Klhdc2
kelch domain containing 2
chr5_+_107437908 0.147 ENSMUST00000094541.2
 Btbd8
BTB (POZ) domain containing 8
chrX_-_10216918 0.141 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
 Rpgr




retinitis pigmentosa GTPase regulator




chr13_-_103920295 0.119 ENSMUST00000169083.1
 Erbb2ip
Erbb2 interacting protein
chr14_+_26514554 0.113 ENSMUST00000104927.1
 Gm2178
predicted gene 2178
chr10_-_26373956 0.109 ENSMUST00000105519.3
ENSMUST00000040219.6
 L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr4_+_5724304 0.103 ENSMUST00000108380.1
 Fam110b
family with sequence similarity 110, member B
chr2_+_143915273 0.085 ENSMUST00000103172.3
 Dstn
destrin
chr8_+_58911755 0.077 ENSMUST00000062978.6
 BC030500
cDNA sequence BC030500
chr17_+_29090969 0.050 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr2_-_60125651 0.048 ENSMUST00000112550.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr6_-_83831736 0.047 ENSMUST00000058383.8
 Paip2b
poly(A) binding protein interacting protein 2B
chr18_+_55057557 0.038 ENSMUST00000181765.1
 Gm4221
predicted gene 4221
chr18_-_38918642 0.033 ENSMUST00000040647.4
 Fgf1
fibroblast growth factor 1
chr5_-_92348871 0.026 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.6 6.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.5 1.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.4 6.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 3.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.0 GO:0002159 desmosome assembly(GO:0002159)
0.3 2.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 5.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 2.7 GO:0007379 segment specification(GO:0007379)
0.3 1.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.2 0.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.6 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.9 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 3.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.5 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 2.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 1.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 2.2 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.4 GO:0007144 female meiosis I(GO:0007144)
0.1 0.5 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 3.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 1.2 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 1.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 1.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.2 GO:0048663 neuron fate commitment(GO:0048663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 GO:0031931 TORC1 complex(GO:0031931)
0.3 0.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 2.0 GO:0071437 invadopodium(GO:0071437)
0.2 8.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 0.6 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.4 GO:0005712 chiasma(GO:0005712)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 11.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0097001 ceramide binding(GO:0097001)
0.3 1.6 GO:0071253 connexin binding(GO:0071253)
0.2 1.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.6 GO:0016015 morphogen activity(GO:0016015)
0.2 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 7.2 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.0 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 5.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)