Motif ID: Foxg1

Z-value: 0.487


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49382791_49382883-0.731.5e-06Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120476469 7.869 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr10_+_22158566 2.471 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr9_+_91378636 2.096 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr12_-_10900296 2.008 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr13_-_3918157 1.770 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr1_-_72874877 1.549 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr4_+_154960915 1.280 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr7_-_115824699 1.139 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr13_-_71963713 1.082 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr18_-_34007206 1.079 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr11_-_89538556 0.883 ENSMUST00000169201.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr15_-_85581809 0.698 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr4_-_108833544 0.695 ENSMUST00000102740.1
ENSMUST00000102741.1
 Btf3l4

basic transcription factor 3-like 4

chr11_+_3488275 0.673 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr6_-_72345144 0.663 ENSMUST00000070345.3
 Usp39
ubiquitin specific peptidase 39
chr3_-_95015214 0.649 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
 Zfp687


zinc finger protein 687


chr10_-_24836165 0.594 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr3_-_95015416 0.594 ENSMUST00000132195.1
 Zfp687
zinc finger protein 687
chr9_+_64121501 0.565 ENSMUST00000118215.1
 Lctl
lactase-like
chr5_+_34369909 0.549 ENSMUST00000180376.1
 Fam193a
family with sequence similarity 193, member A
chr2_-_57124003 0.529 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr5_-_134314678 0.521 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
 Gtf2i







general transcription factor II I







chr6_-_129717132 0.497 ENSMUST00000088046.1
 Klri1
killer cell lectin-like receptor family I member 1
chr16_-_28929658 0.497 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2
chr2_-_164389095 0.490 ENSMUST00000167427.1
 Slpi
secretory leukocyte peptidase inhibitor
chr9_+_106170918 0.489 ENSMUST00000020490.5
 Wdr82
WD repeat domain containing 82
chr5_+_145204523 0.445 ENSMUST00000085671.3
ENSMUST00000031601.7
 Zkscan5

zinc finger with KRAB and SCAN domains 5

chr13_+_34162953 0.444 ENSMUST00000124996.1
ENSMUST00000147632.1
 Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr2_+_174330006 0.436 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
 Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr16_-_90284412 0.428 ENSMUST00000039280.7
 Scaf4
SR-related CTD-associated factor 4
chr16_-_90284300 0.398 ENSMUST00000163419.1
 Scaf4
SR-related CTD-associated factor 4
chr12_-_104751900 0.381 ENSMUST00000041987.6
 Dicer1
dicer 1, ribonuclease type III
chr1_-_180813534 0.372 ENSMUST00000159789.1
ENSMUST00000081026.4
 H3f3a

H3 histone, family 3A

chr19_+_11770415 0.356 ENSMUST00000167199.1
 Mrpl16
mitochondrial ribosomal protein L16
chr14_-_24245913 0.327 ENSMUST00000073687.6
ENSMUST00000090398.4
 Dlg5

discs, large homolog 5 (Drosophila)

chr11_+_72607221 0.321 ENSMUST00000021148.6
ENSMUST00000138247.1
 Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr5_-_121191365 0.281 ENSMUST00000100770.2
ENSMUST00000054547.7
 Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr1_-_84284423 0.273 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr18_+_73859366 0.225 ENSMUST00000120033.1
ENSMUST00000179472.1
ENSMUST00000119239.1
 Mro


maestro


chr4_-_108833608 0.223 ENSMUST00000102742.4
 Btf3l4
basic transcription factor 3-like 4
chr18_+_11839220 0.200 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr1_-_180813591 0.197 ENSMUST00000162118.1
ENSMUST00000159685.1
ENSMUST00000161308.1
 H3f3a


H3 histone, family 3A


chr15_-_95528702 0.184 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr19_+_8617991 0.148 ENSMUST00000010250.2
 Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr18_-_68300329 0.132 ENSMUST00000042852.6
 Fam210a
family with sequence similarity 210, member A
chr9_-_60649793 0.125 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr9_+_54586450 0.114 ENSMUST00000167866.1
 Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr11_-_28583995 0.110 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr3_-_50443603 0.102 ENSMUST00000029297.4
 Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr14_-_121698417 0.075 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr18_-_68300194 0.075 ENSMUST00000152193.1
 Fam210a
family with sequence similarity 210, member A
chr4_+_116720920 0.050 ENSMUST00000045542.6
ENSMUST00000106459.1
 Tesk2

testis-specific kinase 2

chr6_-_12109583 0.024 ENSMUST00000080891.5
 Gm6578
predicted gene 6578

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0060613 fat pad development(GO:0060613)
0.3 1.3 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.7 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.2 1.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.6 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.5 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.8 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:0071335 negative regulation of Schwann cell proliferation(GO:0010626) myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) hair follicle cell proliferation(GO:0071335)
0.1 2.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.3 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.6 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 1.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0001740 Barr body(GO:0001740)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 7.8 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.9 GO:0003680 AT DNA binding(GO:0003680)
0.3 2.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 1.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)