Motif ID: Foxj3_Tbl1xr1

Z-value: 1.672

Transcription factors associated with Foxj3_Tbl1xr1:

Gene SymbolEntrez IDGene Name
Foxj3 ENSMUSG00000032998.10 Foxj3
Tbl1xr1 ENSMUSG00000027630.8 Tbl1xr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj3mm10_v2_chr4_+_119539652_119539698-0.318.2e-02Click!
Tbl1xr1mm10_v2_chr3_+_22076644_220766810.067.2e-01Click!


Activity profile for motif Foxj3_Tbl1xr1.

activity profile for motif Foxj3_Tbl1xr1


Sorted Z-values histogram for motif Foxj3_Tbl1xr1

Sorted Z-values for motif Foxj3_Tbl1xr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_3270767 13.683 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_-_100514800 10.328 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr6_+_141524379 10.263 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr5_+_75152274 9.809 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_57455898 8.092 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr7_+_31059342 7.231 ENSMUST00000039775.7
 Lgi4
leucine-rich repeat LGI family, member 4
chr6_+_138140298 6.167 ENSMUST00000008684.4
 Mgst1
microsomal glutathione S-transferase 1
chr7_+_88278085 6.031 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr6_+_91212799 5.615 ENSMUST00000153364.1
ENSMUST00000132021.1
ENSMUST00000134974.1
 Fbln2


fibulin 2


chr1_+_152399824 5.322 ENSMUST00000044311.8
 Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr18_+_56432116 5.201 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr10_+_3740348 5.048 ENSMUST00000120274.1
 Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_-_162866502 4.912 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr11_+_90030295 4.901 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chr2_+_93642307 4.899 ENSMUST00000042078.3
ENSMUST00000111254.1
 Alx4

aristaless-like homeobox 4

chr12_-_90738438 4.747 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr7_-_4532419 4.665 ENSMUST00000094897.4
 Dnaaf3
dynein, axonemal assembly factor 3
chr4_+_136143497 4.551 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr3_+_106113229 4.514 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chr11_-_79504078 4.432 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,070 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 13.7 GO:0001887 selenium compound metabolic process(GO:0001887)
1.1 13.5 GO:0044458 motile cilium assembly(GO:0044458)
0.1 13.5 GO:0006457 protein folding(GO:0006457)
1.7 13.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.5 12.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 11.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.2 11.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.1 11.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
2.6 10.6 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.3 9.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.9 9.8 GO:0042572 retinol metabolic process(GO:0042572)
1.8 9.2 GO:0015671 oxygen transport(GO:0015671)
1.8 9.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
3.0 8.9 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.6 8.6 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.9 8.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 8.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.3 7.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.2 7.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.8 7.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 368 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 83.3 GO:0043230 extracellular organelle(GO:0043230)
0.2 38.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 35.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 21.4 GO:0016324 apical plasma membrane(GO:0016324)
0.3 20.8 GO:0036126 sperm flagellum(GO:0036126)
0.2 15.8 GO:0031225 anchored component of membrane(GO:0031225)
0.3 14.8 GO:0005604 basement membrane(GO:0005604)
0.1 14.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.5 11.8 GO:0005833 hemoglobin complex(GO:0005833)
1.3 11.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.7 11.1 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 10.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 9.5 GO:0015934 large ribosomal subunit(GO:0015934)
0.6 9.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.7 9.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 8.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.5 8.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 8.1 GO:0031970 organelle envelope lumen(GO:0031970)
0.2 7.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.1 7.8 GO:0097418 neurofibrillary tangle(GO:0097418)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 623 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 23.6 GO:0050840 extracellular matrix binding(GO:0050840)
1.0 15.3 GO:0008430 selenium binding(GO:0008430)
0.8 13.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 13.6 GO:0071837 HMG box domain binding(GO:0071837)
0.7 13.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 12.9 GO:0008168 methyltransferase activity(GO:0008168)
0.4 12.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 11.9 GO:0051015 actin filament binding(GO:0051015)
0.2 11.6 GO:0051082 unfolded protein binding(GO:0051082)
1.6 11.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 10.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.7 10.6 GO:0001968 fibronectin binding(GO:0001968)
2.5 10.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 9.7 GO:0042605 peptide antigen binding(GO:0042605)
1.8 9.2 GO:0005344 oxygen transporter activity(GO:0005344)
1.0 8.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.5 8.5 GO:0017166 vinculin binding(GO:0017166)
0.3 8.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 8.3 GO:0051787 misfolded protein binding(GO:0051787)
0.2 7.8 GO:0030332 cyclin binding(GO:0030332)