Motif ID: Foxk1_Foxj1

Z-value: 0.710

Transcription factors associated with Foxk1_Foxj1:

Gene SymbolEntrez IDGene Name
Foxj1 ENSMUSG00000034227.7 Foxj1
Foxk1 ENSMUSG00000056493.8 Foxk1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxk1mm10_v2_chr5_+_142401484_142401532-0.459.4e-03Click!
Foxj1mm10_v2_chr11_-_116335384_1163353990.373.3e-02Click!


Activity profile for motif Foxk1_Foxj1.

activity profile for motif Foxk1_Foxj1


Sorted Z-values histogram for motif Foxk1_Foxj1

Sorted Z-values for motif Foxk1_Foxj1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxk1_Foxj1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 4.969 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chrX_+_170010744 3.455 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chrY_+_90785442 2.625 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr10_+_97482350 1.505 ENSMUST00000163448.2
 Dcn
decorin
chr14_-_62456286 1.440 ENSMUST00000165651.1
ENSMUST00000022501.3
 Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr16_-_36784924 1.438 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
 Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr12_+_112999964 1.215 ENSMUST00000180971.1
 9230104M06Rik
RIKEN cDNA 9230104M06 gene
chr16_-_36784784 1.124 ENSMUST00000165531.1
 Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr10_-_92165159 1.111 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_+_110099295 1.084 ENSMUST00000134301.1
 Cdh7
cadherin 7, type 2
chr13_+_119606650 1.084 ENSMUST00000178948.1
 Gm21967
predicted gene, 21967
chr19_-_34255325 1.081 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr4_-_154097105 1.061 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
 Trp73


transformation related protein 73


chr15_+_99006056 1.031 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr10_+_4611971 1.021 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr10_-_37138863 0.970 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr1_-_144177259 0.926 ENSMUST00000111941.1
ENSMUST00000052375.1
 Rgs13

regulator of G-protein signaling 13

chr1_+_86045863 0.920 ENSMUST00000165824.1
 2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr10_-_96409038 0.909 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr5_-_135251209 0.890 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 2.6 GO:0042938 dipeptide transport(GO:0042938)
0.0 2.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 1.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 1.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.3 1.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.3 1.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.1 0.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 0.8 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.7 GO:0001302 replicative cell aging(GO:0001302)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.7 GO:0070469 respiratory chain(GO:0070469)
0.2 1.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.0 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.2 0.7 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.6 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.6 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 1.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.3 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.3 1.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 0.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 0.8 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.7 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)