Motif ID: Foxl1

Z-value: 0.483


Transcription factors associated with Foxl1:

Gene SymbolEntrez IDGene Name
Foxl1 ENSMUSG00000097084.1 Foxl1
Foxl1 ENSMUSG00000043867.5 Foxl1



Activity profile for motif Foxl1.

activity profile for motif Foxl1


Sorted Z-values histogram for motif Foxl1

Sorted Z-values for motif Foxl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_45093611 2.252 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr2_-_147186389 2.239 ENSMUST00000109970.3
ENSMUST00000067075.5
 Nkx2-2

NK2 homeobox 2

chr11_+_31872100 1.662 ENSMUST00000020543.6
ENSMUST00000109412.2
 Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr17_-_91092715 1.475 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr10_-_102490418 1.131 ENSMUST00000020040.3
 Nts
neurotensin
chr1_-_170110491 1.080 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr13_-_23622502 1.060 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chr7_+_122289297 0.845 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr2_+_119325784 0.785 ENSMUST00000102517.3
 Dll4
delta-like 4 (Drosophila)
chr16_-_22439570 0.716 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr9_+_71215779 0.630 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr15_+_43477213 0.612 ENSMUST00000022962.6
 Emc2
ER membrane protein complex subunit 2
chr13_+_23763660 0.604 ENSMUST00000055770.1
 Hist1h1a
histone cluster 1, H1a
chr13_+_23738804 0.575 ENSMUST00000040914.1
 Hist1h1c
histone cluster 1, H1c
chr2_+_91256144 0.547 ENSMUST00000154959.1
ENSMUST00000059566.4
 Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr6_-_147264124 0.496 ENSMUST00000052296.6
 Pthlh
parathyroid hormone-like peptide
chrM_+_2743 0.481 ENSMUST00000082392.1
 mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr9_+_44069421 0.471 ENSMUST00000114830.2
 Usp2
ubiquitin specific peptidase 2
chr2_+_91255954 0.469 ENSMUST00000134699.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chrX_-_94123087 0.458 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked
chr13_+_23575753 0.440 ENSMUST00000105105.1
 Hist1h3d
histone cluster 1, H3d
chr16_+_30065333 0.404 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chrX_+_18162575 0.367 ENSMUST00000044484.6
ENSMUST00000052368.8
 Kdm6a

lysine (K)-specific demethylase 6A

chr9_-_101198999 0.367 ENSMUST00000066773.7
 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_56377300 0.346 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chrX_+_112604274 0.269 ENSMUST00000071814.6
 Zfp711
zinc finger protein 711
chr12_+_69963452 0.243 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr4_+_11191726 0.242 ENSMUST00000029866.9
ENSMUST00000108324.3
 Ccne2

cyclin E2

chr2_-_94264745 0.200 ENSMUST00000134563.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr18_+_34409415 0.194 ENSMUST00000166156.1
ENSMUST00000014647.7
 Pkd2l2

polycystic kidney disease 2-like 2

chr13_+_23555023 0.177 ENSMUST00000045301.6
 Hist1h1d
histone cluster 1, H1d
chr16_+_43508118 0.177 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr6_-_134887783 0.007 ENSMUST00000066107.6
 Gpr19
G protein-coupled receptor 19

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 1.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 0.8 GO:0072554 blood vessel lumenization(GO:0072554)
0.3 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.6 GO:0035799 ureter maturation(GO:0035799)
0.2 1.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.1 1.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0060746 parental behavior(GO:0060746)
0.0 0.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.5 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:0008542 visual learning(GO:0008542)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.3 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)