Motif ID: Foxo4

Z-value: 0.799


Transcription factors associated with Foxo4:

Gene SymbolEntrez IDGene Name
Foxo4 ENSMUSG00000042903.7 Foxo4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo4mm10_v2_chrX_+_101254528_1012545740.212.5e-01Click!


Activity profile for motif Foxo4.

activity profile for motif Foxo4


Sorted Z-values histogram for motif Foxo4

Sorted Z-values for motif Foxo4



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo4

PNG image of the network

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Top targets:


Showing 1 to 20 of 81 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_5796924 4.493 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr8_-_105943382 2.597 ENSMUST00000038896.7
Lcat
lecithin cholesterol acyltransferase
chr5_-_70842617 2.493 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr15_-_97767798 1.830 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr8_-_45410539 1.761 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr17_+_78508063 1.607 ENSMUST00000024880.9
Vit
vitrin
chr14_-_25903100 1.587 ENSMUST00000052286.8
Plac9a
placenta specific 9a
chr14_-_26182480 1.562 ENSMUST00000184142.1
Plac9b
placenta specific 9b
chr2_-_175931051 1.524 ENSMUST00000108949.2
ENSMUST00000109018.2
Gm8898

predicted gene 8898

chr2_-_175141999 1.504 ENSMUST00000109062.1
ENSMUST00000109059.1
ENSMUST00000109060.1
Gm14399


predicted gene 14399


chr10_-_53638269 1.386 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chr2_-_175338197 1.319 ENSMUST00000121393.2
Gm4631
predicted gene 4631
chr2_+_176521056 1.261 ENSMUST00000108997.2
ENSMUST00000178443.1
Gm14431

predicted gene 14431

chr2_+_175469985 1.256 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr11_+_101246960 1.240 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr2_-_177957239 1.222 ENSMUST00000108928.1
ENSMUST00000108932.1
ENSMUST00000108930.2
Gm14326


predicted gene 14326


chr2_+_175372436 1.213 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr4_-_97778042 1.193 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_175703646 1.176 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr18_-_38918642 1.172 ENSMUST00000040647.4
Fgf1
fibroblast growth factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 4.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 2.6 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 2.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.6 1.8 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.5 1.8 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.4 1.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.8 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.8 GO:0060074 synapse maturation(GO:0060074)
0.0 0.7 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0016607 nuclear speck(GO:0016607)
0.1 2.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 1.8 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.6 2.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.3 0.8 GO:0030172 troponin C binding(GO:0030172)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)