Motif ID: Foxp1_Foxj2

Z-value: 1.900

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.954.1e-17Click!
Foxp1mm10_v2_chr6_-_99266494_992665400.521.9e-03Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 35.750 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr14_-_51913393 18.614 ENSMUST00000004673.7
ENSMUST00000111632.3
 Ndrg2

N-myc downstream regulated gene 2

chr18_+_69344503 12.950 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr2_+_136713444 12.890 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr5_+_122643878 12.571 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr8_+_66386292 11.284 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr4_-_151108244 10.154 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr16_-_4880284 9.628 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr6_-_58907120 9.420 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr15_-_58214882 9.221 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr16_+_91269759 9.120 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr15_-_66969616 8.879 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr7_+_16310412 8.798 ENSMUST00000136781.1
 Bbc3
BCL2 binding component 3
chr11_+_54438188 8.732 ENSMUST00000046835.7
 Fnip1
folliculin interacting protein 1
chr19_-_34255325 8.587 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr7_+_110772604 8.548 ENSMUST00000005829.6
 Ampd3
adenosine monophosphate deaminase 3
chr6_+_135362931 8.344 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr14_-_62456286 7.909 ENSMUST00000165651.1
ENSMUST00000022501.3
 Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr9_-_121495678 7.880 ENSMUST00000035120.4
 Cck
cholecystokinin
chr4_-_87806296 7.735 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 399 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 37.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.2 19.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 17.8 GO:0006376 mRNA splice site selection(GO:0006376)
1.3 17.4 GO:0070842 aggresome assembly(GO:0070842)
1.7 16.7 GO:0042118 endothelial cell activation(GO:0042118)
0.2 15.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.7 14.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 14.7 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.7 14.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 13.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.7 12.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
4.2 12.6 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.4 12.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 12.0 GO:0042572 retinol metabolic process(GO:0042572)
0.4 11.9 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.1 11.2 GO:0007379 segment specification(GO:0007379)
2.7 10.9 GO:0042938 dipeptide transport(GO:0042938)
1.1 10.9 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.8 10.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.2 10.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 158 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 51.4 GO:0060076 excitatory synapse(GO:0060076)
0.1 29.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.7 18.4 GO:0031931 TORC1 complex(GO:0031931)
0.6 17.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 15.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.0 13.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 13.7 GO:0030425 dendrite(GO:0030425)
3.2 12.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 12.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 12.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 12.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 11.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.8 11.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
1.1 11.1 GO:0044327 dendritic spine head(GO:0044327)
0.2 10.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 10.3 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.2 10.0 GO:0031941 filamentous actin(GO:0031941)
0.1 9.7 GO:0045202 synapse(GO:0045202)
0.3 9.5 GO:0035861 site of double-strand break(GO:0035861)
2.6 7.9 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 264 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.9 GO:0017124 SH3 domain binding(GO:0017124)
0.8 20.2 GO:0017075 syntaxin-1 binding(GO:0017075)
4.1 16.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 15.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
2.2 13.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.7 13.1 GO:0042287 MHC protein binding(GO:0042287)
2.1 12.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.8 12.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 12.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 11.3 GO:0005096 GTPase activator activity(GO:0005096)
2.2 10.9 GO:0042895 antibiotic transporter activity(GO:0042895)
0.3 10.8 GO:0045296 cadherin binding(GO:0045296)
1.0 10.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
3.4 10.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 10.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
2.5 10.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.0 9.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 9.8 GO:0017137 Rab GTPase binding(GO:0017137)
1.6 9.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 9.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)