Motif ID: Foxp2_Foxp3
Z-value: 0.512
Transcription factors associated with Foxp2_Foxp3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxp2 | ENSMUSG00000029563.10 | Foxp2 |
| Foxp3 | ENSMUSG00000039521.6 | Foxp3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxp2 | mm10_v2_chr6_+_14901440_14901497 | 0.27 | 1.3e-01 | Click! |
| Foxp3 | mm10_v2_chrX_+_7579666_7579693 | -0.04 | 8.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 194 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.5 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.4 | 2.7 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.2 | 2.7 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 2.6 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.2 | 2.5 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.2 | 2.2 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.1 | 2.0 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.3 | 1.8 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.2 | 1.8 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.2 | 1.6 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.2 | 1.6 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.2 | 1.6 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.3 | 1.5 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.2 | 1.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 1.5 | GO:0010828 | positive regulation of glucose transport(GO:0010828) |
| 0.5 | 1.4 | GO:1901254 | positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.1 | 1.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.1 | 1.4 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 1.4 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.3 | 1.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 71 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 2.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.5 | 1.4 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.3 | 1.0 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.3 | 1.0 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 1.0 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.1 | 0.9 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 0.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.8 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 0.6 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 113 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.9 | 2.7 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.6 | 2.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.3 | 1.8 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.2 | 1.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.4 | 1.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 1.6 | GO:0008430 | selenium binding(GO:0008430) |
| 0.3 | 1.5 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.3 | 1.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.3 | 1.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 1.3 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.3 | 1.2 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.3 | 1.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 1.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.4 | 1.1 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
| 0.3 | 1.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 1.1 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 1.1 | GO:0070888 | E-box binding(GO:0070888) |
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