Motif ID: Gata3

Z-value: 1.594


Transcription factors associated with Gata3:

Gene SymbolEntrez IDGene Name
Gata3 ENSMUSG00000015619.10 Gata3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata3mm10_v2_chr2_-_9878580_9878607-0.531.4e-03Click!


Activity profile for motif Gata3.

activity profile for motif Gata3


Sorted Z-values histogram for motif Gata3

Sorted Z-values for motif Gata3



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 11.446 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr11_-_98329641 9.503 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr11_+_58948890 8.784 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr16_-_23890805 8.731 ENSMUST00000004480.3
 Sst
somatostatin
chr10_-_81472859 8.535 ENSMUST00000147524.1
ENSMUST00000119060.1
 Celf5

CUGBP, Elav-like family member 5

chr4_+_13751297 7.265 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_29253001 6.514 ENSMUST00000071201.4
 Ntng2
netrin G2
chr3_+_94478831 6.302 ENSMUST00000029784.5
 Celf3
CUGBP, Elav-like family member 3
chr7_+_126950837 5.733 ENSMUST00000106332.1
 Sez6l2
seizure related 6 homolog like 2
chr2_-_65567465 5.659 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr7_-_30534180 5.613 ENSMUST00000044338.4
 Arhgap33
Rho GTPase activating protein 33
chr2_-_65567505 5.609 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr14_-_55116935 5.518 ENSMUST00000022819.5
 Jph4
junctophilin 4
chr4_+_9269285 5.495 ENSMUST00000038841.7
 Clvs1
clavesin 1
chr7_+_126950518 5.382 ENSMUST00000106335.1
ENSMUST00000146017.1
 Sez6l2

seizure related 6 homolog like 2

chr1_+_152954966 5.137 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_132707304 5.114 ENSMUST00000043189.7
 Nfasc
neurofascin
chr4_+_43669610 4.926 ENSMUST00000107866.1
 Tmem8b
transmembrane protein 8B
chr8_-_106337987 4.756 ENSMUST00000067512.7
 Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr3_+_18054258 4.696 ENSMUST00000026120.6
 Bhlhe22
basic helix-loop-helix family, member e22

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 327 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 15.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 13.6 GO:0006342 chromatin silencing(GO:0006342)
0.7 11.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.3 11.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 9.6 GO:0006334 nucleosome assembly(GO:0006334)
3.2 9.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 9.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
2.0 8.2 GO:0007412 axon target recognition(GO:0007412)
0.1 7.4 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.7 7.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.4 7.3 GO:0021542 dentate gyrus development(GO:0021542)
1.2 7.2 GO:0032796 uropod organization(GO:0032796)
0.5 7.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
1.0 6.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 6.6 GO:0008542 visual learning(GO:0008542)
0.1 6.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.8 5.8 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.1 5.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 5.5 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
1.1 5.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 141 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.8 GO:0060076 excitatory synapse(GO:0060076)
0.5 15.5 GO:0000788 nuclear nucleosome(GO:0000788)
1.0 15.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 14.8 GO:0043025 neuronal cell body(GO:0043025)
0.4 10.8 GO:0030673 axolemma(GO:0030673)
0.9 9.5 GO:0045298 tubulin complex(GO:0045298)
0.2 8.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 8.0 GO:0000786 nucleosome(GO:0000786)
0.1 7.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 7.3 GO:0042734 presynaptic membrane(GO:0042734)
1.4 7.2 GO:0030314 junctional membrane complex(GO:0030314)
0.1 6.9 GO:0008021 synaptic vesicle(GO:0008021)
0.7 6.7 GO:0044327 dendritic spine head(GO:0044327)
0.2 6.5 GO:0060077 inhibitory synapse(GO:0060077)
0.7 6.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 5.9 GO:0031091 platelet alpha granule(GO:0031091)
0.1 5.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 5.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 5.4 GO:0001891 phagocytic cup(GO:0001891)
0.6 5.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 217 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 13.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 13.5 GO:0031402 sodium ion binding(GO:0031402)
0.1 13.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.5 11.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 10.1 GO:0001540 beta-amyloid binding(GO:0001540)
1.0 8.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 8.6 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.6 7.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 6.8 GO:0005267 potassium channel activity(GO:0005267)
0.2 6.2 GO:0005179 hormone activity(GO:0005179)
0.2 6.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 5.8 GO:0030674 protein binding, bridging(GO:0030674)
0.3 5.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 5.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 5.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.3 5.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.0 5.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 5.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 5.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)